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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-FEB-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS13750 [old locus tag: SPAP_1940 ]
  • pan locus tag?: PNEUPAN003523000
  • symbol: SPAP_RS13750
  • pan gene symbol?: ABC-NBD-truncation_3
  • synonym:
  • product: ABC transporter permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS13750 [old locus tag: SPAP_1940 ]
  • symbol: SPAP_RS13750
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1812602..1813423
  • length: 822
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (1812602..1813423) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCG
    ACCTATATCTCGAAAATTACGGATTTGCTAGGTAGTCAAGGAACTAATTTAGATGAGTTG
    TGGCAGCCGGCAAGCATGATGATGGGAATGCCCTTTCTTGCCTTCTTGTCCGTAGTTGCA
    GTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
    TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTC
    TTGATGCGTACTACCAATGACATTACTCAAGTTCAAATGTTGATTACTATGGACTTGCAA
    GTGGTAACGTGTGGTCCAATTATGGCTATCTGGGCTATTGGGAAGATTTTAGGTCATTCA
    GAATACTGGCTCTGGGCCGTACTTGTGGCAGTGATTGTCAACGTCCTGATGACGACCGTT
    TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGCTGACAGATAAACTGAAC
    AGTATCACTCGTGAGAGTTTAACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGAT
    TATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGACCCGTTTAAATTTGTTTGTC
    AACCGTCTTATGGCTATTTTGAATCCTATCATGATGGGGATTTCAAGTGGTTTGAGTGTG
    GCGATTTACTGGATTGGGGCCTATGTGATTAACGACGCTGCTCCGATAGCGCGTCTGCCT
    CTCTTTAGTGACATGATTGTTTTCATGTCTTATGCCATGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    822

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS13750 [old locus tag: SPAP_1940 ]
  • symbol: SPAP_RS13750
  • description: ABC transporter permease
  • length: 273
  • theoretical pI: 5.26315
  • theoretical MW: 30545
  • GRAVY: 0.613919

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 54.4)
    Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 54.4)
    Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 46.6)
    ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 44.8)
    and 11 more
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 39.3)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 39.3)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 26.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 19.7)
    Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 19.7)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 19.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 19.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 18.9)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 18.9)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 18.9)
    thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 15.7)
  • TheSEED: see SPAP_1940
  • PFAM:
    ABC_membrane (CL0241) ABC_membrane; ABC transporter transmembrane region (PF00664; HMM-score: 94)
    and 1 more
    no clan defined Chloroplast_duf; Petal formation-expressed (PF14476; HMM-score: 10.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018193
    • TAT(Tat/SPI): 0.000214
    • LIPO(Sec/SPII): 0.014185
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000601689 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPASMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLMRTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTVLMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNLFVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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