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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1000 [new locus tag: SPCG_RS05190 ]
  • pan locus tag?: PNEUPAN002045000
  • symbol: SPCG_1000
  • pan gene symbol?: tsaC
  • synonym:
  • product: Sua5/YciO/YrdC family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1000 [new locus tag: SPCG_RS05190 ]
  • symbol: SPCG_1000
  • product: Sua5/YciO/YrdC family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 974069..974698
  • length: 630
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    TTGGTCAAAATAGGATGGTTGTGGTTGATGATGGACAAGATTAGACAAGAGTTGGAAAAT
    GGTGGAGCTGTCGTTCTACCTACAGAGACGGTTTACGGTCTTTTTGCTAAGGCCTTAGAT
    GAAAAAGCAGTTGACCATGTTTACCAACTCAAACGTCGTCCCAGAGATAAGGCACTCAAT
    CTCAATATCGCCTCTTTCGAGGATATCTTGCACTTTTCTAAGAATCAGCCAACTTATCTA
    CAAAAACTTGTAGAGACCTTTTTGCCAGGTCCCTTGACCATTATTCTCGAAGCCAATGAC
    CGAGTTCCCTATTGGGTAAATTCTGACCTTGCAACTATTGGATTTCGGATGCCCAGTCAC
    CCTATCACACTGGATTTAATTCGAGAGACAGGTCCCTTGATTGGGCCGTCTGCCAATATC
    TCAGGTCAGGCAAGTGGTGTAACCTTTGAACAAATTCTGAAGGATTTTGACCAAGAGGTT
    CTGGGTCTGGAAGACGATGCTTTTCTAACTGGACAGGATTCAACTATTGTGGATTTGTCT
    GGAGACAAGGTGAAAATCTTACGCCAAGGTGCAATTAAACGAGAAGATATTCTTGCTCGG
    TTGCCAGAGATTTCTTTTGAGGAGGCTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    630

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPCG_1000 [new locus tag: SPCG_RS05190 ]
  • symbol: SPCG_1000
  • description: Sua5/YciO/YrdC family protein
  • length: 209
  • theoretical pI: 4.62774
  • theoretical MW: 23432.8
  • GRAVY: -0.100478

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family (TIGR00057; HMM-score: 173.8)
  • TheSEED  :
    • TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
    RNA Metabolism RNA processing and modification tRNA modification Archaea  TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
    and 2 more
    RNA Metabolism RNA processing and modification YrdC-YciO  TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
    RNA Metabolism RNA processing and modification YrdC-YciO-Sua5 and associated protein families  TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA
  • PFAM:
    no clan defined Sua5_yciO_yrdC; Telomere recombination (PF01300; HMM-score: 160.5)
    and 1 more
    FrhB_FdhB_N; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term (PF04422; HMM-score: 11.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9993
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0006
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004711
    • TAT(Tat/SPI): 0.000189
    • LIPO(Sec/SPII): 0.000622
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACB90252 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MVKIGWLWLMMDKIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRRPRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLTGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]