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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1296 [new locus tag: SPCG_RS06700 ]
  • pan locus tag?: PNEUPAN000161000
  • symbol: SPCG_1296
  • pan gene symbol?: pezA_2
  • synonym:
  • product: transcriptional regulator, putative

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1296 [new locus tag: SPCG_RS06700 ]
  • symbol: SPCG_1296
  • product: transcriptional regulator, putative
  • replicon: chromosome
  • strand: -
  • coordinates: 1283289..1283765
  • length: 477
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGATTGGAAAGAACATAAAATCCTTGCGTAAAACACATGACTTAACACAACTCGAATTT
    GCACGGATTGTAGGTATTTCACGAAATAGTCTGAGTCGTTATGAAAATGGAACGAGTTCA
    GTCTCTACCGAATTAATAGACATCATTTGTCAGAAGTTTAATGTATCTTATGTCGATATT
    GTAGGAGAAGATAAAATGCTCAATCCTGTTGAAGATTATGAATTGACTTTAAAAATTGAA
    ATTGTGAAAGAAAGAGGTGCTAATCTATTATCTCGACTCTATCGTTATCAAGATAGTCAG
    GGAATTAGCATTGATGATGAATCTAATCCTTGGATTTTAATGAGTGATGATCTATCTGAC
    TTGATTCATACGAATATCTATTTAGTAGAAACTTTTGATGAAATAGAGAGATATAGTGGC
    TATTTGGATGGAATTGAACGTATGTTAGAGATATTTGAAAAACGGATGGCAGCCTAA
    60
    120
    180
    240
    300
    360
    420
    477

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_1296 [new locus tag: SPCG_RS06700 ]
  • symbol: SPCG_1296
  • description: transcriptional regulator, putative
  • length: 158
  • theoretical pI: 4.41891
  • theoretical MW: 18279.6
  • GRAVY: -0.301266

⊟Function[edit | edit source]

  • TIGRFAM:
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 37.5)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 34)
    and 3 more
    Genetic information processing Mobile and extrachromosomal element functions Other addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.1)
    Signal transduction Regulatory functions DNA interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.1)
    Signal transduction Regulatory functions Protein interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 13.1)
  • TheSEED  :
    • transcription regulator, probable
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 50.9)
    and 9 more
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 38.2)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 33.1)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 31.7)
    MqsA_antitoxin; Antitoxin component of bacterial toxin-antitoxin system, MqsA (PF15731; HMM-score: 25.1)
    HTH_60; Helix-turn-helix domain (PF20317; HMM-score: 14.7)
    Xre-like-HTH; Antitoxin Xre-like helix-turn-helix domain (PF20432; HMM-score: 13.6)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 13.3)
    HTH_37; Helix-turn-helix domain (PF13744; HMM-score: 12.5)
    Nckap1_CYFIP1-2 (CL0715) Nckap1; Nck-associated protein 1 (PF09735; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006828
    • TAT(Tat/SPI): 0.000973
    • LIPO(Sec/SPII): 0.001341
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTELIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEIFEKRMAA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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