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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1657 [new locus tag: SPCG_RS08575 ]
  • pan locus tag?: PNEUPAN003081000
  • symbol: SPCG_1657
  • pan gene symbol?: nanP
  • synonym:
  • product: PTS system, IIBC components

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1657 [new locus tag: SPCG_RS08575 ]
  • symbol: SPCG_1657
  • product: PTS system, IIBC components
  • replicon: chromosome
  • strand: -
  • coordinates: 1627495..1629027
  • length: 1533
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    GTGAGGGGGAGTTTTATGTTTAAAGTTTTACAAAAAGTTGGAAAAGCTTTTATGTTACCT
    ATAGCTATACTTCCTGCAGCAGGTCTACTTTTGGGGATTGGTGGTGCACTTTCAAACCCA
    ACCACGATAGCAACTTATCCAATACTAGACAATAGTATTTTTCAATCAATATTCCAAGTA
    ATGAGCTCTGCAGGAGAGGTTGTATTCAGTAATTTGTCACTACTTCTCTGTGTGGGATTA
    TGTATTGGCTTAGCGAAACGAGATAAAGGAACCGCTGCGTTAGCAGGAGTAACTGGTTAC
    TTAGTTATGACTGCAACGATCAAAGCTTTAGTAAAACTTTTTATGGCAGAAGGATCTGCA
    ATTGATACTGGAGTTATTGGAGCATTAGTTGTCGGAATAGTTGCCGTATATTTGCACAAC
    CGATATAACAATATTCAATTACCTTCCGCTTTAGGATTCTTTGGAGGTTCACGCTTCGTT
    CCTATTGTTACATCGTTCTCTTCTATCTTGATTGGCTTTGTCTTCTTTGTTATTTGGCCA
    CCTTTCCAACAACTTCTTGTTTCTACAGGTGGATATATTTCTCAGGCGGGTCCAATTGGA
    ACTTTTCTATATGGATTTTTAATGAGACTTTCTGGAGCAGTAGGCTTACATCATATAATT
    TACCCTATGTTTTGGTATACTGAACTTGGTGGTGTTGAAACTGTTGCAGGACAAACAGTG
    GTTGGAGCTCAAAAAATATTTTTTGCTCAATTAGCCGATTTGGCCCATTCTGGATTATTT
    ACAGAAGGAACAAGGTTTTTTGCAGGTCGTTTCTCAACAATGATGTTCGGTTTACCGGCT
    GCCTGTTTAGCGATGTACCATAGTGTTCCTAAAAATCGTCGTAAAAAATACGCGGGTTTG
    TTTTTTGGAGTTGCTTTAACATCTTTTATTACCGGTATTACAGAACCAATTGAATTTATG
    TTTCTATTCGTCAGTCCGGTTCTATATGTTGTTCACGCATTCCTTGATGGTGTTAGCTTC
    TTTATTGCAGACGTCTTAAATATTTCAATAGGAAACACATTTTCAGGAGGTGTAATCGAT
    TTCACTTTATTTGGAATTTTGCAGGGGAACGCTAAGACGAATTGGGTTCTTCAGATTCCA
    TTTGGACTTATTTGGAGTGTTTTGTATTATATTATTTTTAGATGGTTCATTACTCAATTC
    AACGTTCTAACGCCAGGACGAGGAGAAGAAGTAGATTCTAAAGAAATTTCTGAATCCGCA
    GATTCAACTTCAAATATTGCAGATTATTTAAAACAGGATAGCCTACAAATTATCAGAGCC
    TTGGGTGGATCAAATAATATAGAAGATGTAGATGCTTGTGTGACACGTTTACGTGTAGCT
    GTAAAAGAAGTTAATCAAGTTGATAAAGCACTTTTAAAACAAATTGGTGCAGTTGATGTC
    TTAGAAGTGAAGGGTGGCATTCAAGCAATCTATGGAGCAAAAGCAATCTTATATAAAAAT
    AGTATTAATGAAATTTTAGGTGTAGATGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1533

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_1657 [new locus tag: SPCG_RS08575 ]
  • symbol: SPCG_1657
  • description: PTS system, IIBC components
  • length: 510
  • theoretical pI: 8.27223
  • theoretical MW: 55061.1
  • GRAVY: 0.641569

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 511.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 437.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 426.3)
    and 9 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 270.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 263.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 245.6)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 245.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 61.7)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 61.7)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 43.5)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 34.3)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 31.6)
  • TheSEED  :
    • PTS system, N-acetylmannosamine-specific IIB component (EC 2.7.1.69)
    • PTS system, N-acetylmannosamine-specific IIC component
    Cell Wall and Capsule Capsular and extracellular polysacchrides Sialic Acid Metabolism  PTS system, N-acetylglucosamine-specific IIA component
    and 2 more
    Cell Wall and Capsule Capsular and extracellular polysacchrides Sialic Acid Metabolism  PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69)
    Cell Wall and Capsule Capsular and extracellular polysacchrides Sialic Acid Metabolism  PTS system, N-acetylglucosamine-specific IIC component
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 265.5)
    and 1 more
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 45.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • SignalP: Signal peptide SP(Sec/SPI) length 38 aa
    • SP(Sec/SPI): 0.573664
    • TAT(Tat/SPI): 0.038306
    • LIPO(Sec/SPII): 0.071984
    • Cleavage Site: CS pos: 38-39. ALS-NP. Pr: 0.4000
  • predicted transmembrane helices (TMHMM): 12

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MRGSFMFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPILDNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATIKALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTSFSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPMFWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAACLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVSFFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFITQFNVLTPGRGEEVDSKEISESADSTSNIADYLKQDSLQIIRALGGSNNIEDVDACVTRLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: RpiR* (repression) regulon, NanR* (repression) regulon, CcpA regulon
    RpiR*(TF)important in Sialic acid utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    NanR*(TF)important in Sialic acid utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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