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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_RS00765 [old locus tag: SPCG_0140 ]
  • pan locus tag?: PNEUPAN000819000
  • symbol: SPCG_RS00765
  • pan gene symbol?: —
  • synonym:
  • product: asparagine synthase-related protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_RS00765 [old locus tag: SPCG_0140 ]
  • symbol: SPCG_RS00765
  • product: asparagine synthase-related protein
  • replicon: chromosome
  • strand: +
  • coordinates: 139099..140637
  • length: 1539
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010582 (139099..140637) NCBI
  • BioCyc: SPCG_RS00765 BioCyc
  • MicrobesOnline: see SPCG_0140
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGGAAAATACTTTATTGAATATCACAGGAAGCTTCGATATGGAAACTAGGAATCTAATT
    AGTTATTCTTTAACTGATATCTTTGAAACAGATAAAATAAGAATTGAACTTCTTGGAGAA
    ATTTATTATAAAAATATAAAGTTGGAATTGCATGAATTCGCTGGATTGTATAAGATTTAT
    GGAATTAGCTTAATAAAGAATATTACCGGAATGTTTTTAATTATAATTTTTGATACGAAG
    ACAAAAGAATTAAAAATTTTTCAAGATATAACGACTTCATACTTTAATTTATACTATACT
    GTTTATGGAGGTGTGTTCTATTATAGTACATCTTTAAAGAAAGTGATGAAGTTATCTCAT
    GTTCCCGTTACCTTAAATAACAAAAAAATACAAGAATTTATGAGAAATGGATTTATTTTA
    GATTCAAATACTTTAGTAACCGAAATTAATAAATTAGAATATTTCTCTTACATTTCTGTA
    AATAATACTCTTCGTATATGTGGTATTGATTATAATGATTCAAACAATTTTACTAAAGAA
    CAAGTATTAAAGAATTGGGACTCTATGCTACGTGAATCTATATTAAGAGTGTATAGTGAA
    GCAGGAGAGGCTAATATTACACTATCATCTGGTTTTGATTCAAATTATATATTATATACA
    TTAGCGAATTATACGAATTCTTCAATTAATGCATTTTGCATAGGAGGAGAAAAAGGAATT
    AATGAGATTCCTGAAGTAACTAAAATTGCAAAATTTTATGGTATAAATTTATTAGTTGAT
    ACTGTAATGAGCCAAGATTTAGAATATTTTCCCGATATAGTATGGAGATTGGAAGGAAGT
    CTCTTTGAATGTGGTGTCATACTGCAGTACTATTTAGGCAGGTTGTTGTTCCAAAAAGGG
    AACACAAGTATTCTTTGTGGCGAGTCAGCGGATGAAATAATGACTTTTAAGTATCATTCT
    GTGAACTACAATCAATTTTGTAATGATAAACAGAAGTCAGTATATTTTAGTTATTCCGAC
    TATCCATTTTATGTTACAAATTCAATTGTTTTAAAGAAAAATAGCCTACTTTTGCATAGT
    TTTGGCATTCATCCTAGATATCCATATAAAATGTCTGAGATTGTTGAAATGTCTAAAAAA
    ATATCAGATCTAAACGATAAAAAAGAATTTCACAAAAAGAACTGTGAGTTGAGGTTTCAA
    GATAGTGTTCTTGATAACATAAATAGTGTCCCGGGTACAACTCATTTATTTAGTTGTTTA
    AATATTCAAACATTAGTAAAAATTATTTTATATATTTTTCGATACAACAGTTGTATGAAA
    ATATTTAATTTTAGAGATAAAGAGCTTATCTTTTTTAATAAGATTGTAAATGGGCTGATA
    CAAAATATTGAGGAGAATTTAGAGGATGATATTGAAAGGATATTGAAATATTTATATATA
    TGTTTATTTAACGAAATATTCATTATTAAGAATAAGGTGAATTTTTTTGATGATGTGGAA
    TTTAATCAGACACTTAGTGAATTTTTAGATAAATTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1539

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_RS00765 [old locus tag: SPCG_0140 ]
  • symbol: SPCG_RS00765
  • description: asparagine synthase-related protein
  • length: 512
  • theoretical pI: 5.56129
  • theoretical MW: 59912.6
  • GRAVY: -0.0837891

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family asparagine synthase (glutamine-hydrolyzing) (TIGR01536; EC 6.3.5.4; HMM-score: 85.4)
    and 2 more
    exosortase A system-associated amidotransferase 1 (TIGR03108; HMM-score: 59.3)
    asparagine synthase family amidotransferase (TIGR03104; HMM-score: 35.7)
  • TheSEED: see SPCG_0140
  • PFAM:
    HUP (CL0039) Asn_synthase; Asparagine synthase (PF00733; HMM-score: 51.4)
    and 2 more
    NTN (CL0052) GATase_7; Glutamine amidotransferase domain (PF13537; HMM-score: 18)
    no clan defined X; Trans-activation protein X (PF00739; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.413
    • Cytoplasmic Membrane Score: 0.1531
    • Cell wall & surface Score: 0.0016
    • Extracellular Score: 0.4323
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001611
    • TAT(Tat/SPI): 0.000103
    • LIPO(Sec/SPII): 0.000662
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_012386605 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MENTLLNITGSFDMETRNLISYSLTDIFETDKIRIELLGEIYYKNIKLELHEFAGLYKIYGISLIKNITGMFLIIIFDTKTKELKIFQDITTSYFNLYYTVYGGVFYYSTSLKKVMKLSHVPVTLNNKKIQEFMRNGFILDSNTLVTEINKLEYFSYISVNNTLRICGIDYNDSNNFTKEQVLKNWDSMLRESILRVYSEAGEANITLSSGFDSNYILYTLANYTNSSINAFCIGGEKGINEIPEVTKIAKFYGINLLVDTVMSQDLEYFPDIVWRLEGSLFECGVILQYYLGRLLFQKGNTSILCGESADEIMTFKYHSVNYNQFCNDKQKSVYFSYSDYPFYVTNSIVLKKNSLLLHSFGIHPRYPYKMSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTTHLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIERILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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