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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 16-DEC-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae CGSP14
- locus tag: SPCG_RS05890 [old locus tag: SPCG_1137 ]
- pan locus tag?: PNEUPAN002385000
- symbol: SPCG_RS05890
- pan gene symbol?: lplA
- synonym:
- product: lipoate--protein ligase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPCG_RS05890 [old locus tag: SPCG_1137 ]
- symbol: SPCG_RS05890
- product: lipoate--protein ligase
- replicon: chromosome
- strand: +
- coordinates: 1108215..1109204
- length: 990
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010582 (1108215..1109204) NCBI
- BioCyc: SPCG_RS05890 BioCyc
- MicrobesOnline: see SPCG_1137
- PneumoBrowse for strain D39V: SPV_1024 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGAAATACATTATCAATCATTCAAATGACACTGCTTTTAATATTGCCTTGGAAGAATAC
GCCTTTAAACACCTTTTGGATGAGGATCAAATCTTCCTACTTTGGATTAACAAGCCATCT
ATCATTGTTGGTCGTCACCAGAACACTATCGAAGAAATCAACCGTGATTATGTTCGCGAA
AATGGTATTGAGGTAGTTCGCCGTATTAGTGGTGGTGGAGCTGTTTACCACGATTTAAAT
AACCTCAACTACACGATCATCTCCAAAGAAGATGAAAATAAGGCATTTGACTTCAAGAGC
TTCTCAACTCCGGTTATCAATACCTTGGCTCAACTTGGGGTTAAAGCTGAGTTCACAGGT
CGTAATGACCTTGAGATTGATGGTAAGAAGTTCTGTGGCAATGCCCAAGCCTATATCAAC
GGCCGTATCATGCACCACGGTTGCTTGCTCTTTGACGTTGATTTGTCAGTCCTCGCAAAT
GCCCTTAAGGTTTCAAAAGATAAATTTGAATCAAAAGGTGTGAAATCCGTCCGTGCCCGT
GTAACCAATATTATCAATGAATTACCAAAAAAAATCACAGTCGAAAAATTCCGTGATTTA
CTCTTGGAATACATGAAAAAAGAGTACCCAGAGATGACTGAATACGTCTTTTCAGAAGAA
GAATTGGCCGAAATCAATCACATCAAGGATACTAAGTTTGGAACTTGGGACTGGAACTAT
GGTAAATCACCTGAATTTAACGTCCGTCGTGGAACCAAATTCACTAGTGGTAAGGTTGAA
GTCTTTGCTAACATTACTGAATCAAAAATCCAAGACATCAAGATTTATGGTGACTTCTTT
GGTATTGAAGACGTTGCTGCAGTAGAAGATGTCCTTCGTGGGGTGAAATACGAACGCGAA
GATGTTCTTAAGGCGCTAAAAACCATTGATATCACACGCTACTTCGCTGGTATTAGCCGT
GAAGAAATCGCTGAAGCGGTAGTTGGATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPCG_RS05890 [old locus tag: SPCG_1137 ]
- symbol: SPCG_RS05890
- description: lipoate--protein ligase
- length: 329
- theoretical pI: 5.52171
- theoretical MW: 37718.6
- GRAVY: -0.343465
⊟Function[edit | edit source]
- TIGRFAM: Protein fate Protein modification and repair lipoyltransferase and lipoate-protein ligase (TIGR00545; HMM-score: 329.5)
- TheSEED: see SPCG_1137
- PFAM: SufE_NifU (CL0233) Lip_prot_lig_C; Bacterial lipoate protein ligase C-terminus (PF10437; HMM-score: 96.6)and 2 moretRNA_synt_II (CL0040) BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family (PF03099; HMM-score: 30.7)no clan defined Med10; Transcription factor subunit Med10 of Mediator complex (PF09748; HMM-score: 12.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9411
- Cytoplasmic Membrane Score: 0.001
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0578
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001871
- TAT(Tat/SPI): 0.000082
- LIPO(Sec/SPII): 0.000364
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000873985 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVGRHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFSTPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLANALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFSEEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANITESKIQDIKIYGDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1024 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]