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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 49619
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ATCC 700669
serotype 23F
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HU-OH
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Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_0227
  • pan locus tag?:
  • symbol: SPD_0227
  • pan gene symbol?: —
  • synonym:
  • product: iron(III) ABC transporter, iron-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_0227
  • symbol: SPD_0227
  • product: iron(III) ABC transporter, iron-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 216514..216708
  • length: 195
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP000410 (216514..216708) NCBI
  • BioCyc:
  • MicrobesOnline: 2017174 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAACATCGAAGGATATAGCGACCTTCTCAAACCTGAACTAAAAGGAAAAATCGCAACT
    GCTGACCCAGCAAACTCTTCTAGCGCCTTTGCTCAATTAACAAATATGCTACAAGCTCAA
    GGTGGTTACAAAGATGATAAGGCTTGGTCTTATGTAAAAGATCTTTTCACACTTATTGAT
    GGTATAGTAAAATGA
    60
    120
    180
    195

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_0227
  • symbol: SPD_0227
  • description: iron(III) ABC transporter, iron-binding protein
  • length: 64
  • theoretical pI: 4.83007
  • theoretical MW: 6981.9
  • GRAVY: -0.271875

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 35.4)
    and 4 more
    2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 17.4)
    Metabolism Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 11.9)
    putative thymidine phosphorylase (TIGR02645; EC 2.4.2.4; HMM-score: 10.8)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 10.7)
  • TheSEED  :
    • Fe(3+) ABC transporter (EC 7.2.2.7), substrate-binding protein
    Iron acquisition and metabolism Iron acquisition and metabolism - no subcategory Iron acquisition in Streptococcus  Ferric iron ABC transporter, iron-binding protein
  • PFAM:
    PBP (CL0177) SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 24.1)
    and 2 more
    SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 18.8)
    SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 16.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0005
    • Cytoplasmic Membrane Score: 0.0158
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.9834
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.04363
    • TAT(Tat/SPI): 0.005344
    • LIPO(Sec/SPII): 0.004242
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNIEGYSDLLKPELKGKIATADPANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGIVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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