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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 02-MAY-2018
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39
- locus tag: SPD_0503 [new locus tag: SPD_RS02705 ]
- pan locus tag?: PNEUPAN001505000
- symbol: bglA-2
- pan gene symbol?: bglA-2
- synonym:
- product: 6-phospho-beta-glucosidase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPD_0503 [new locus tag: SPD_RS02705 ]
- symbol: bglA-2
- product: 6-phospho-beta-glucosidase
- replicon: chromosome
- strand: +
- coordinates: 511111..512526
- length: 1416
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000410 (511111..512526) NCBI
- BioCyc: see SPD_RS02705
- MicrobesOnline: 2017435 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0503 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1381ATGACCATTTTTCCAGATGATTTTCTTTGGGGTGGAGCTGTTGCAGCTAATCAAGTAGAA
GGAGCATATAATGAAGATGGTAAGGGCTTATCAGTTCAGGATGTGTTACCCAAAGGTGGA
TTAGGAGAAGCAACAGAAAATCCTACAGAAGATAACTTAAAATTGATAGGTATTGATTTT
TATCATAAATATAAGGAAGATATATCCTTGTTTTCTGAAATGGGCTTTAATGTTTTTCGT
ACTTCTATTGCATGGAGTAGAATTTTTCCAAAAGGAGATGAGGAAGAACCTAACGAAGCT
GGGTTGAAATATTATGATGAATTGTTTGATGAACTACATGCTCACGGGATAGAACCACTT
GTAACTCTTTCACACTATGAGACTCCATTATATTTAGCAAGAAAATATCATGGATGGATT
GATAGGAGAATGATTCATTTTTATGAAAAATTTGCTCGAACAGTTTTAGAAAGGTATAAA
GATAAAGTTAAATATTGGCTTACATTTAACGAAGTAAACTCTGTTTTGGAATTACCGTTT
ACTAGTGGAGGAATAGATATACCTAAGGAGAATCTTTCGAAACAAGAATTATATCAAGCT
ATACATCATGAATTAGTCGCCTCGAGTTTGGTTACAAAAATTGCTCGTGAGATTAATTCA
GAGTTTAAGGTGGGGTGTATGGTATTAGCTATGCCAGCTTATCCAATGACTCCAAATCCA
AAAGATGTATGGGCGACTCATGAGTATGAGAATCTAAATTATCTATTTTCAGATGTGCAT
GTTAGAGGTTATTATCCGAATTATGCAAAAAGATATTTTAAGGAACATGACATTAACATA
GAGTTTGCAGCTGAAGATGCAGAGTTATTAAAAAATTATACCGTAGATTTTTTATCCTTT
AGCTATTACATGAGTGTGACTCAATCTGCTCTTCCAACACAGTATAATTCAGGAGAAGGG
AATATTATTGGTGGCTTAGTAAATCCTTATTTAGAGTCTTCTGAGTGGGGATGGCAAATT
GATCCAATTGGACTACGTATAATTTTAAATAGATATTATGACCGTTATCAAATTCCATTA
TTTATAGTGGAAAACGGATTAGGTGCTAAAGATCAACTAATAAAAGATGAATTTAATAAC
TTAACAGTCCAAGATGATTATAGAATTCAGTATATGAAAGAACATTTATTGCAAGTAGCT
GAAGCTCTACAAGATGGTGTGGAAATTATGGGCTATACGTCTTGGGGATGTATTGACTGT
GTTTCTATGTCCACTGCACAACTTTCTAAAAGGTACGGTCTCATTTATGTTGATCGAAAT
GATGATGGAAATGGCACATTCAATCGATATAAGAAAATGTCCTTTACTTGGTATAAAGGA
GTGATTGAATCAAATGGAGAATCCTTATTCAAATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPD_0503 [new locus tag: SPD_RS02705 ]
- symbol: BglA-2
- description: 6-phospho-beta-glucosidase
- length: 471
- theoretical pI: 4.69498
- theoretical MW: 54420.9
- GRAVY: -0.402972
⊟Function[edit | edit source]
- reaction: EC 3.2.1.86? ExPASy6-phospho-beta-glucosidase 6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate
- TIGRFAM: beta-galactosidase (TIGR03356; HMM-score: 294.4)Energy metabolism Biosynthesis and degradation of polysaccharides 6-phospho-beta-galactosidase (TIGR01233; EC 3.2.1.85; HMM-score: 241.8)
- TheSEED :
- 6-phospho-beta-glucosidase (EC 3.2.1.86)
- PFAM: Glyco_hydro_tim (CL0058) Glyco_hydro_1; Glycosyl hydrolase family 1 (PF00232; HMM-score: 453.2)and 1 moreCellulase; Cellulase (glycosyl hydrolase family 5) (PF00150; HMM-score: 26.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.025219
- TAT(Tat/SPI): 0.006667
- LIPO(Sec/SPII): 0.006536
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEATENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGLKYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYKDKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREINSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEHDINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESSEWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYMKEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRYKKMSFTWYKGVIESNGESLFK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: licT > SPD_0502 > bglA-2
⊟Regulation[edit | edit source]
- regulator: CcpA regulon
CcpA (TF) important in Global catabolite repression; RegPrecise transcription unit transferred from TIGR4 data RegPrecise
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0503 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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