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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_0521 [new locus tag: SPD_RS02795 ]
  • pan locus tag?: PNEUPAN001494000
  • symbol: vex1
  • pan gene symbol?: vex1
  • synonym:
  • product: ABC transporter, transmembrane protein Vexp1

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_0521 [new locus tag: SPD_RS02795 ]
  • symbol: vex1
  • product: ABC transporter, transmembrane protein Vexp1
  • replicon: chromosome
  • strand: +
  • coordinates: 531181..532458
  • length: 1278
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAATCCAATCCAAAGATCTTGGGCTTATGTCAGCAGAAAGCGACTGAGAAGTTTTATT
    TTATTTCTGATTTTATTGGTCTTATTGGCCGGAATTTCAGCCTGTTTGACTCTGATGAAG
    TCCAACAAAACAGTAGAAAGCAATCTTTATAAATCACTCAATACATCTTTTTCTATTAAG
    AAGATAGAGAATGGTCAGACATTCAAGTTGTCAGACCTAGCATCTGTAAGCAAGATTAAG
    GGGCTGGAAAATGTCTCTCCTGAACTTGAGACGGTCGCAAAACTAAAAGACAAGGAAGCA
    GTGACTGGCGAGCAGAGCGTGGAGCGTGATGATTTATCAGCTGCAGACAATAACTTGGTT
    AGCTTAACGGCTCTTGAGGATTCATCCAAGGATGTAACCTTTACCAGTTCGGCTTTCAAT
    CTAAAAGAAGGGCGACACCTTCAAAAAGGGGATTCCAAGAAAATCCTTATCCACGAAGAA
    TTGGCTAAGAAGAACGGTCTTTCACTTCATGACAAGATTGGCTTGGATGCTGGTCAGTCT
    GAATCTGGAAAAGGACAAACAGTAGAGTTTGAGATTATTGGCATCTTTTCTGGTAAAAAA
    CAAGAGAAATTCACAGGCTTGTCTTCTGACTTCAGTGAAAATCAAGTCTTTACAGACTAT
    GAAAGTAGCCAAACCCTTTTGGGCAATAGTGAAGCTCAAGTCAGTGCAGCACGCTTCTAT
    GTAGAAAATCCTAAGGAAATGGACGGACTCATGAAGCAGGTAGAAAACTTGGCCTTGGAA
    AATCAAGGCTACCAAGTCGAAAAGGAAAACAAGGCTTTTGAACAAATCAAAGACTCAGTT
    GCAACTTTCCAAACCTTCCTGACCATCTTCCTTTATGGGATGTTGATAGCAGGAGCTGGA
    GCCTTAATTCTGGTTTTGTCTCTCTGGTTGAGAGAACGGGTCTATGAAGTGGGGATTTTA
    CTTGCACTTGGAAAAGGCAAGAGCTCGATCTTCCTACAATTCTGTTTAGAGGTAGTTTTG
    GTATCTCTTGGAGCTTTGCTTCCAGCATTTGTTGCAGGAAACGCAATCACAACTTACCTA
    CTCCAAACTCTACTAGCAAGTGGAGATCAGGCAAGCTTACAAGATACACTAGCCAAAGCA
    AGCAGTTTATCAACTAGCATCTTATCTTTTGCAGAATCCTATGTTTTTCTAGTTCTGCTT
    AGTTGCTTATCTGTAGCCCTTTGTTTCCTATTCTTATTTAGAAAATCACCGAAAGAAATT
    TTATCATCTATTAGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1278

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_0521 [new locus tag: SPD_RS02795 ]
  • symbol: Vex1
  • description: ABC transporter, transmembrane protein Vexp1
  • length: 425
  • theoretical pI: 5.91219
  • theoretical MW: 46564.3
  • GRAVY: 0.110353

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 36.8)
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 31.7)
  • TheSEED  :
    • ABC transporter membrane-spanning permease, Pep export, Vex1
    Virulence, Disease and Defense Resistance to antibiotics and toxic compounds Streptococcus pneumoniae Vancomycin Tolerance Locus  ABC transporter membrane-spanning permease, Pep export, Vex1
  • PFAM:
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 46.5)
    and 4 more
    no clan defined CCB1; Cofactor assembly of complex C subunit B (PF12046; HMM-score: 15.1)
    Phage_barrel (CL0504) DUF2001; Phage tail tube protein (PF09393; HMM-score: 14.7)
    ABC-2 (CL0181) ABC2_membrane_2; ABC-2 family transporter protein (PF12679; HMM-score: 10.2)
    no clan defined DHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 7.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9927
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0071
  • SignalP: Signal peptide LIPO(Sec/SPII) length 34 aa
    • SP(Sec/SPI): 0.02094
    • TAT(Tat/SPI): 0.001075
    • LIPO(Sec/SPII): 0.930895
    • Cleavage Site: CS pos: 34-35. ISA-CL. Pr: 0.9311
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKTVESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVTGEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEELAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFTDYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQIKDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQFCLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAESYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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