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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_0784 [new locus tag: SPD_RS04190 ]
  • pan locus tag?: PNEUPAN001858000
  • symbol: SPD_0784
  • pan gene symbol?: hsdR_2
  • synonym:
  • product: type I restriction-modification system, R subunit, putative

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_0784 [new locus tag: SPD_RS04190 ]
  • symbol: SPD_0784
  • product: type I restriction-modification system, R subunit, putative
  • replicon: chromosome
  • strand: +
  • coordinates: 796483..799833
  • length: 3351
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    ATGGGAAATTTTAGCTTTCTTTTAAAAAATGACGAATATGAATCTTTTTCAAAACCTTGC
    ATTGAAGCTGAGAATATGATTGCTACATCAACTGTGGCTACTGCCTTTATGGCGCGTCGT
    GCTTTAGAGCAGGCTGTCCATTGGATATATAGTCACGATTCATATTTAGAAGCTCCCTAT
    CGTGCTACTCTATCTTCTTTAGTATGGGATGATGATTTTAGGGATATCGTAGATTCTGAA
    CTCCACAAGCAGATAGTTCTGTTGATTCGGTGGGGAAACCATGCTGCTCATGGTGGTGAA
    ATTAAGGAACGAGAAGCGATTTTAGCTTTGCATCATTTGTATCAGTTTGTTAATTTTATC
    GATTATTGTTACAGCAATGAGTTTGTGGAGCGTTATTTTGATGAGAAGTGCTTACCACTT
    TCAGCAAACATCAAATACCGAGAAACTCCACAATCTATGATAAAGTTACAAGACAGTTTA
    CCAGAACTGCCTGATTTTCATGAACAGATGGCTGCTCAGTCCGTAGAAGTTCAAGAGACT
    TATACTGAAAAACGTGAGACTGCAGCGCAACGGCAAGATGTGCCTTTCCATATTGATCAA
    TTATCTGAGGCAGAGACAAGAAAGCTCTTTATTGATATCGATCTCCGTTTAGCAGGATGG
    ATATTTGAAGAAAACTGTCGTGTTGAGATAGCCGTTGATGGTCTCAAGCACGGTTCAGGA
    ATTGGTTACTGTGACTATGTACTTTATGGTAAAAATGGGAAAATTTTAGCGATTGTGGAG
    GCTAAAAAAGCCTCTGTCAATCCAGAAGTAGGGGAAGTACAGGTCAAAGAATATGCTGAA
    GCTTTGGAGAAACATATCGGCTATCAGCCAATTTGCTTTATTACAAATGGGTTGAAGCAC
    TATATACTTGATGGTCCGAACCGCCGCCAGATTGCAGGCTTTTACTCTCAAGAAGAATTG
    CAATTAGTGATGGATAGACGTCATCTTCAAAAACCACTTGAGGATATTTCTAGTAAAATT
    AGGGACGATATTTCCGGGCGTCACTACCAAAAACATGCCATTGCAAGCGTTTGTGAAGCT
    TTCTCTAATCATCGTAGACAGGCACTTTTGGTTATGGCAACTGGGGCTGGGAAAACTCGT
    ACAGCAGTTTCTCTAGTTGATATCTTATCACGTCATAACTGGGTAAAAAACGTTCTCTTC
    TTAGCCGATAGAACTTCCTTGGTTAAGCAAGCATATGATTCGTTTAGAAAATTACTCCCA
    GATCTTTCCGTTTGTAACTTCTTAGAAGATAAAGAAGGAGCTCAATCAAGTCGCATGGTC
    TTTTCAACTTATCCGACCATGATTGGAGCGATTAGTGGTCAAGAAGAAGTAAATCAACGC
    CCTTTCACTGTTGGGCATTTTGACCTTATCATAATTGACGAATCTCACCGTTCTATTTAT
    CAGAAATACAAGTCCATTTTTGATTATTTTGATGCAAGAATTGTAGGCTTAACAGCTACT
    CCGCGTCAAGATTTAGATAAAAACACCTATGGATTCTTTAATTTGGAGAATGGGGTTCCA
    ACATATGCATATGATTTGGAAGAGGCTGTTAAAGACGGATATTTAGTAGCCTATCATTCT
    ATCGAAACCAAACTGAAACTACCTACGGATGGTCTACATTATGATGATTTGTCCGAAGAA
    GAAAAGGAACATTTTGATAGCAAATTTGAAGACGATAGCTGTGAAAAAGATATTGATGGG
    AGTGTATTTAATTCCTTTGTTTTCAATAAAAGTACAGTAGAAATTGTTTTAAATGAACTC
    ATGACAAGAGGAATTCAGACAGCCTCGGGTGATGAAATTGGTAAAACTATTATTTTTGCT
    AAAAATCATGATCATGCAGAATATATCAGAGGTATTTTTAACAACCGCTATCCTGAAAAA
    GGGAGCGACTATGCTCAGGTGATTGATTATAGTATTAAGCATTATCAGACCTTGATTGAT
    GATTTTAAAATTGAGGAGAAGTATCCTCAAATTGCGATTTCTGTCGATATGTTAGATACA
    GGTATTGATGTACCAGAGGTTGTTAATTTAGTCTTCTTCAAGAAAGTACGCTCTAAAACT
    AAGTTTTGGCAGATGATTGGTCGAGGAACCCGTCTATGTAAAGATTTATTTGGACCTGAG
    CAGGATAAGGAAAACTTCTTGGTATTTGATTATGGGGATAATTTTGATTATTTTCGTGCA
    GATCCAAGAGATGGAGAGGGTCGTCACATTGTTTCGTTGACTCAGCGTTTATTTAATATC
    AAAGTGGACTTGATTCGAGAACTTCAGGGACTCCAATACCAAGAAGATCAGTTTGCGAGA
    GCATACCGTCAGCAGCTTGTCTCGGAACTTCAAGGTCGTATAGAGAGCTTAAATGAGTTG
    GACTTCAGGGTTCGTATGGTTTTAGATACAGTTTATAGCTATAGGAAATTGGAAAGTTGG
    CAGAATCTAACTGCTGTTACAAGTGAAACCATTCAAAAAAATCTCTCTCCGCTTTTATTT
    GATGAAGATAAAGAAGATGAGATGGCCAGGAGATTTGATTTGTGGTTGCTTCATATTCAG
    TTGGGGCAACTGACAGCTAAATCTTCCACTGTTCATATTTCCCAAGTGATGAAGACGGCT
    AGAGCTCTTTCTGCTATTGGCAATATCCCGCAGGTTTTTGAGCAGGCTGAAATTATCAGG
    AAAGTACAGGAGCCTGAATTTTGGAAAGAAGTTAACTTGTCTGATTTGGAAAAAATTCGT
    CTTGCTATTCGAGATTTATTACAGTTTTTGGATAAAACAGACCGTAAACCCTACTATGTT
    AACCTTGAAGATCGTATACTCTCCACTGTTCACGAGACCACAGCATTTTTGCAGGTCAAC
    GATCTTCGGTCTTACAATGAAAAAGTTGAGCATTATTTGAAAACTCATCTGGATGAGGAG
    TCCATTTCTAAGCTATACCATAATAAAAAGTTGACATCTGATGATATGCTTGCACTTGAA
    AAATTGCTTTGGGAAAAATTAGGTAGTAAAGCAGACTACCAAAGTCATTATGAAAATAAG
    GCAATTCCGAGATTGGTTCGTGAGATTATTGGCTTAGATAGAGAGTCTGCCAATCGTATT
    TTTTCTAAATTTTTGTCGGATGAGAATCTTAATGCCAGGCAGATTTCATTTGTAAAATTG
    ATTGTAGACTACATTGTAGAAAATGGTTTTTTAGAGACGAAAGTGTTAACGCAAGAGCCG
    TTTAAATCTTATGGTTCTGTTCAACTACTCTTCCAACACCAACTACCAGTACTTCGTAAT
    ATTGTTCAAATCATTGAACTTATCAATAATCGAGCTGGAGAAGCGGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3351

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_0784 [new locus tag: SPD_RS04190 ]
  • symbol: SPD_0784
  • description: type I restriction-modification system, R subunit, putative
  • length: 1116
  • theoretical pI: 5.32776
  • theoretical MW: 129232
  • GRAVY: -0.405556

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism Restriction/modification type I site-specific deoxyribonuclease, HsdR family (TIGR00348; EC 3.1.21.3; HMM-score: 62.9)
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 52.3)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit B (TIGR00631; EC 3.1.25.-; HMM-score: 29.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecG (TIGR00643; EC 3.6.4.12; HMM-score: 18.6)
  • TheSEED  :
    • Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
    DNA Metabolism DNA Metabolism - no subcategory Restriction-Modification System  Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
    and 1 more
    DNA Metabolism DNA Metabolism - no subcategory Type I Restriction-Modification  Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
  • PFAM:
    P-loop_NTPase (CL0023) ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 122.6)
    and 11 more
    SWI2_SNF2; SWI2/SNF2 ATPase (PF18766; HMM-score: 64)
    no clan defined EcoEI_R_C; EcoEI R protein C-terminal (PF08463; HMM-score: 54)
    PDDEXK (CL0236) HSDR_N; Type I restriction enzyme R protein N terminus (HSDR_N) (PF04313; HMM-score: 41.8)
    P-loop_NTPase (CL0023) DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 38)
    Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 36.3)
    KNTase_C (CL0291) DUF4145; Domain of unknown function (DUF4145) (PF13643; HMM-score: 31.9)
    PDDEXK (CL0236) HSDR_N_2; Type I restriction enzyme R protein N terminus (HSDR_N) (PF13588; HMM-score: 23.8)
    P-loop_NTPase (CL0023) AAA_16; AAA ATPase domain (PF13191; HMM-score: 14.1)
    no clan defined LPD3; Large polyvalent protein-associated domain 3 (PF18798; HMM-score: 14)
    MazG (CL0231) dUTPase_2; dUTPase (PF08761; HMM-score: 13.1)
    P-loop_NTPase (CL0023) DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9027
    • Cytoplasmic Membrane Score: 0.0586
    • Cell wall & surface Score: 0.0018
    • Extracellular Score: 0.0368
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004287
    • TAT(Tat/SPI): 0.000669
    • LIPO(Sec/SPII): 0.000645
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQAVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIKEREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSLPELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLAGWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVKEYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLEDISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRHNWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGAISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKNTYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFDSKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHDHAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGIDVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRADPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLNELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWLLHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVNLEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEAA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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