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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 02-MAY-2018
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39
- locus tag: SPD_1791 [new locus tag: SPD_RS09540 ]
- pan locus tag?: PNEUPAN003614000
- symbol: SPD_1791
- pan gene symbol?: aspC_2
- synonym:
- product: aminotransferase, class I
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPD_1791 [new locus tag: SPD_RS09540 ]
- symbol: SPD_1791
- product: aminotransferase, class I
- replicon: chromosome
- strand: -
- coordinates: 1785880..1787094
- length: 1215
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000410 (1785880..1787094) NCBI
- BioCyc: see SPD_RS09540
- MicrobesOnline: 2018642 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1791 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1201ATGAAAGAATATAACAAGTCTAGTAAGTTAGAGCATGTTGCTTATGATATCCGTGGTCCT
GTATTGGAAGAAGCCATGCGGATGCGAGCGAATGGAGAAAAGATTTTACGTCTGAATACA
GGAAATCCAGCAGAATTTGGCTTTACAGCGCCAGACGAGGTCATTCATGACTTGATTATG
AATGCGCGTGATAGTGAAGGCTATTCTGACTCCAAAGGAATTTTCTCAGCCCGTAAGGCC
ATCATGCAGTATTGCCAGCTGAAGAAATTCCCAAACGTAGATATTGATGATATTTACCTT
GGAAATGGTGTCAGTGAGTTGATTGTCATGTCCATGCAGGGGCTTTTGGACAATGGGGAT
GAGGTCTTAGTGCCAATGCCAGACTATCCTCTATGGACGGCGGCTGTCAGCCTAGCTGGA
GGAAATGCCGTTCACTATATCTGTGATGAAGCTGTTGAATGGTACCCAGATATTGACGAT
ATCAAGTCAAAAATCACTTCCAATACCAAGGCAATCGTCCTTATCAATCCAAATAACCCA
ACTGGAGCCCTTTATCCTAAGGAACTCTTGCTGGAGATTATTGAGATTGCCCGTCAAAAT
GATTTGATTATCTTTGCGGATGAAATCTATGACCGCATGGTAATGGACGGACATGTGCAT
ACGCCTGTGGCGAGCTTGGCACCAGATGTCTTCTGTGTCAGCATGAATGGTCTGTCAAAA
TCCCACCGCATAGCAGGTTTCCGTGTGGGTTGGATGGTCTTGTCTGGCCCTAAGACTCAT
GTTAAGGGCTATATCGAAGGGCTCAATATGCTGTCCAATATGCGCCTTTGCTCTAACGTT
TTGGCCCAACAAGTCGTACAAACTTCCTTGGGGGGTCACCAATCAGTCGATGAATTGCTT
CTTCCTGGTGGACGAATCTACGAGCAAAGAAATTTCATCTATAATGCCATTCAAGATATT
CCAGGTTTGTCTGCCGTTAAACCCAAGGCGGGGCTCTATATCTTCCCAAAAATCGACCGC
AATATGTACCGTATCGATGATGATGAGCAGTTTGTCCTTGATTTCTTGAAGCAGGAAAAG
GTTCTCTTGGTTCATGGTCGAGGCTTTAACTGGCAGGAACCAGACCACTTCCGTATCGTT
TACCTTCCTCGTGTTGATGAGTTAGCCCAAATCCAAGAAAAGATGACTCGTTTCTTGAAA
CAGTATCGTAGATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPD_1791 [new locus tag: SPD_RS09540 ]
- symbol: SPD_1791
- description: aminotransferase, class I
- length: 404
- theoretical pI: 5.63607
- theoretical MW: 45741.3
- GRAVY: -0.199752
⊟Function[edit | edit source]
- TIGRFAM: tyrosine/nicotianamine family aminotransferase (TIGR01265; HMM-score: 227.3)Energy metabolism Amino acids and amines tyrosine aminotransferase (TIGR01264; EC 2.6.1.5; HMM-score: 217.1)and 17 moreLL-diaminopimelate aminotransferase (TIGR03540; EC 2.6.1.83; HMM-score: 137.5)putative C-S lyase (TIGR04350; EC 4.4.-.-; HMM-score: 96)Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 94.2)succinyldiaminopimelate transaminase (TIGR03538; EC 2.6.1.17; HMM-score: 86.3)Cellular processes Biosynthesis of natural products capreomycidine synthase (TIGR03947; HMM-score: 84.1)succinyldiaminopimelate transaminase (TIGR03537; EC 2.6.1.17; HMM-score: 77.2)succinyldiaminopimelate transaminase (TIGR03539; EC 2.6.1.17; HMM-score: 69.2)Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 67.1)LL-diaminopimelate aminotransferase (TIGR03542; EC 2.6.1.83; HMM-score: 61.7)beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 58.7)Energy metabolism Amino acids and amines aspartate 4-decarboxylase (TIGR03801; EC 4.1.1.12; HMM-score: 29.2)enduracididine biosynthesis enzyme MppQ (TIGR04461; EC 2.-.-.-; HMM-score: 24.7)Unknown function Enzymes of unknown specificity cysteine desulfurase family protein (TIGR01977; HMM-score: 23.7)Energy metabolism Amino acids and amines methionine gamma-lyase (TIGR01328; EC 4.4.1.11; HMM-score: 14.3)enduracididine biosynthesis enzyme MppP (TIGR04462; EC 2.-.-.-; HMM-score: 13.9)cysteine desulfurase NifS (TIGR03402; EC 2.8.1.7; HMM-score: 11.4)Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin glutamate-1-semialdehyde-2,1-aminomutase (TIGR00713; EC 5.4.3.8; HMM-score: 10.1)
- TheSEED :
- Alanine transaminase (EC 2.6.1.2)
Amino Acids and Derivatives Alanine, serine, and glycine Alanine biosynthesis Alanine transaminase (EC 2.6.1.2)and 2 more - PFAM: PLP_aminotran (CL0061) Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 152)and 4 moreAminotran_5; Aminotransferase class-V (PF00266; HMM-score: 18.6)DegT_DnrJ_EryC1; DegT/DnrJ/EryC1/StrS aminotransferase family (PF01041; HMM-score: 18.5)MHC (CL0343) MHC_II_alpha; Class II histocompatibility antigen, alpha domain (PF00993; HMM-score: 13.7)PLP_aminotran (CL0061) Beta_elim_lyase; Beta-eliminating lyase (PF01212; HMM-score: 10.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9876
- Cytoplasmic Membrane Score: 0.0041
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0082
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.009111
- TAT(Tat/SPI): 0.001066
- LIPO(Sec/SPII): 0.00128
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDDIKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLKQYRR
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1791 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]