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serotype 4
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Hu15
serotype 19A
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serotype 19A
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serotype 14
JJA
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MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
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serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_1992 [new locus tag: SPD_RS10540 ]
  • pan locus tag?: PNEUPAN003835000
  • symbol: SPD_1992
  • pan gene symbol?: manX_4
  • synonym:
  • product: PTS system, IIA component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_1992 [new locus tag: SPD_RS10540 ]
  • symbol: SPD_1992
  • product: PTS system, IIA component
  • replicon: chromosome
  • strand: -
  • coordinates: 1968491..1968934
  • length: 444
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    TTGAAAGAGAAAATGTTTAATAGAGGAATTTTAGTTGCCAGTCATGGTAATTTTGCTAGC
    GGAGCTCTCATGACCGCAGAAATGTTTGTTGGTGAGACAACAAATGATAGAGTTAGGACA
    TTAGGTTTGATGCCTGGAGAGAATATTGTAGAGTTTGAACATTATTTTAAAAATCAAGTA
    AATGAACTGTTAGACTCAAATCAAGAGGTTATCGTTTTGACTGACTTGATTGGAGGAAGT
    CCTAATAATGTGGCTTTGTCACGGTTTTTAAATTTGGATTCAGTTGATATTGTAACAGGG
    TTTAATATCCCTCTCCTAGTGGAATTAATATCAAGTTATGATTCAAAAATCAATTTAGAA
    GAAATTGTTCACAATGCTCAAAATAGTTTGTTTAATGTTAAACAACAACTTAACGTAGAG
    GAGGAAGAGGATTTATGTCTATAG
    60
    120
    180
    240
    300
    360
    420
    444

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_1992 [new locus tag: SPD_RS10540 ]
  • symbol: SPD_1992
  • description: PTS system, IIA component
  • length: 147
  • theoretical pI: 4.13391
  • theoretical MW: 16431.5
  • GRAVY: -0.0278912

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 71)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 71)
  • TheSEED  :
    • PTS system, L-fucose-specific IIA component (EC 2.7.1.69)
    Carbohydrates Monosaccharides L-fucose utilization  Predicted L-fucose-specific phosphotransferase system, EIIA component
  • PFAM:
    EDD (CL0245) EIIA-man; PTS system fructose IIA component (PF03610; HMM-score: 108.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.072103
    • TAT(Tat/SPI): 0.023202
    • LIPO(Sec/SPII): 0.032368
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEKMFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGENIVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLLVELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: FucR* (repression) regulon, CcpA regulon
    FucR*(TF)important in Fucose utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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