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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_RS09795 [old locus tag: SPD_1841 ]
  • pan locus tag?: PNEUPAN003625000
  • symbol: SPD_RS09795
  • pan gene symbol?: ulaR
  • synonym:
  • product: transcription antiterminator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_RS09795 [old locus tag: SPD_1841 ]
  • symbol: SPD_RS09795
  • product: transcription antiterminator
  • replicon: chromosome
  • strand: -
  • coordinates: 1826777..1828450
  • length: 1674
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_008533 (1826777..1828450) NCBI
  • BioCyc: G1G6V-2001 BioCyc
  • MicrobesOnline: see SPD_1841
  • PneumoBrowse for strain D39V: SPV_1841 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGGTACTGGATAAGGCAAGTTGTGATTTGCTTCAATATTTGATGGATCAAGAAACGTCC
    AAAACGATTATGGCAATTTCGAAAGATTTGAAAGAGTCAAGAAGGAAAATTTATTATCAC
    ATTGACAAAATCAATGCTGCTCTGGGTGACGAGGCGCTTCACATCATTAGTATTCCACGA
    ATTGGTATTCACTTAACGGAAGAGCAGAGAGATGCTTGTTGTAAACTATTATCGGAAGTA
    GATTCGTACGATTATATCATGAGTGCGCATGAACGTATGATGATAATGTTACTATGGATA
    GGTATTTCTAAAGAACGTATTACGATTGAAAAATTGATAGAGTTAACAGAGGTATCTAGG
    AATACTGTTCTCAATGATTTGAATAGCATTCGTTATCAACTAACTTTGGAACAATATCAG
    GTGACCTTGCAAGTGAGCAAGTCACAGGGATACCACCTTCATGCCCACCCTCTTAATAAA
    ATTCAGTATCTTCAATCGCTTCTATATCATATTTTTATGGAAGAAAATGCCACTTTTGTA
    TCTATTTTAGAAGATAAGATGAAAGAGAGGTTAGATGATGAGTGTTTGCTTTCTGTTGAA
    ATGAACCAATTTTTTAAGGAACAGGTTCCTTTAGTTGAACAAGATTTAGGGAAGAAAATA
    AATCATCATGAAATAACTTTTATGTTGCAGGTTCTACCTTATTTGCTGTTAAGCTGTCAT
    AATGTTGAACAGTATCAAGAAAGACATCAGGATATAGAGAAAGAATTTTCTTTGATAAGA
    AAAAGAATAGAGTATCAGGTGTCTAAGAAATTAGGAGAACGGTTGTTTCAAAAGTTTGAA
    ATTTCTTTGTCAGGACTTGAAGTTTCTCTTGTAGCTGTTCTCCTCCTCTCCTATCGTAAA
    GATTTGGATATTCATGCAGAAAGTGATGATTTTCGGCAATTAAAACTTGCTTTAGAAGAA
    TTTATCTGGTATTTTGAATCACAAATCCGAATGGAGATTGAGAACAAGGATGATTTGTTA
    CGAAATTTGATGATCCACTGTAAATCCTTGTTATTTAGAAAGACTTACGGTATTTTTTCT
    AAAAATCCTCTAACAAAACAAATTCGATCCAAGTATGGAGAATTATTTTTAGTCACTAGA
    AAATCTGCGGAAATTTTAGAAGGAGCATGGTTTATTCGGCTAACAGACGATGATATTGCC
    TATTTGACGATTCATATTGGAGGATTTTTAAAGTATACACCATCGTCTCAAAAAAATATG
    AAAAAAGTTTATCTCGTTTGTGATGAAGGTGTTGCGGTTTCGAGACTTTTGCTGAAACAA
    TGCAAACTTTATTTTCCAAATGAGCAAATTGACACTGTATTTACAACAGAACAATTTAAG
    AGTGTGGAAGATATTGCACAAGTTGATGTAGTGATTACTACTAATGATGATTTGGATAGC
    AGATTTCCGATTTTAAGGGTTAATCCTATCCTTGAAGCAGAAGATATTTTGAAAATGCTA
    GACTATCTTAAACACAATATATTTCGTAATGAGAGCAAAAGTTTCAGTGAAAATCTTTCT
    AGTCTTATTTCGTCTTATATTGTAGACAGCAAGTTGGCTAGTAAGTTCCAAGAAGAGGTT
    CAAACACTTATAAATCAAGAAATAGTAGTTCAAGCTTTTTTGGAAGATATTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1674

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_RS09795 [old locus tag: SPD_1841 ]
  • symbol: SPD_RS09795
  • description: transcription antiterminator
  • length: 557
  • theoretical pI: 5.42883
  • theoretical MW: 65325.1
  • GRAVY: -0.189048

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SPD_1841
  • PFAM:
    PRD (CL0166) PRD; PRD domain (PF00874; HMM-score: 93.8)
    and 7 more
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 34.2)
    Phosphatase (CL0031) PTS_IIB; PTS system, Lactose/Cellobiose specific IIB subunit (PF02302; HMM-score: 17.6)
    HTH (CL0123) HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 15.1)
    HTH_Mga; M protein trans-acting positive regulator (MGA) HTH domain (PF08280; HMM-score: 12.9)
    no clan defined RNA_binding; RNA binding (PF01877; HMM-score: 12.1)
    BTRD1; Bacterial tandem repeat domain 1 (PF17660; HMM-score: 12)
    HTH (CL0123) Mga; Mga helix-turn-helix domain (PF05043; HMM-score: 10.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by UlaR*, TF important in Ascorbate utilization: see SPD_1841

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00091
    • TAT(Tat/SPI): 0.000421
    • LIPO(Sec/SPII): 0.000355
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKINAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGISKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNKIQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGKKINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLFQKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIENKDDLLRNLMIHCKSLLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFIRLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQIDTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIFRNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Muhammad Afzal, Sulman Shafeeq, Birgitta Henriques-Normark, Oscar P Kuipers
UlaR activates expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid.
Microbiology (Reading): 2015, 161(Pt 1);41-49
[PubMed:25355938] [WorldCat.org] [DOI] (I p)Sulman Shafeeq, Muhammad Afzal, Birgitta Henriques-Normark, Oscar P Kuipers
Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae.
Genom Data: 2015, 4;57-9
[PubMed:26484177] [WorldCat.org] [DOI] (P e)

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