TIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 30-JAN-2014

⊟Summary

• organism: Streptococcus pneumoniae G54
• locus tag: SPG_0229
• pan locus tag^?:
• symbol: SPG_0229
• pan gene symbol^?: —
• synonym:
• product: iron ABC transporter, iron-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPG_0229
• symbol: SPG_0229
• product: iron ABC transporter, iron-binding protein
• replicon: chromosome
• strand: -
• coordinates: 213066..213434
• length: 369
• essential: unknown

⊟Accession numbers

• Location: CP001015 (213066..213434) NCBI
• BioCyc:
• MicrobesOnline: 5755498 MicrobesOnline
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  
  ATGGCTGTTGGTCTCTCTTATGAGGATCCAGCAGTTAAACTCTTAAATGACGGAGCTAAC
  ATTAAAGTAGTCTATCCAAAAGAAGGAACCGTCTTCCTACCTGCTAGTGCTGCTATCGTT
  AAAAAAGCTAAAAATATGGAAAATGCCAAGAAATTTATCGATTTTATTATCTCTCAAGAA
  GTACAAGATACACTTGGTACAACCACTACTAACCGTCCTGTTCGTAAAAATGCTAAAACA
  AGCGAAAACATGAAACCAATTGACAAAATCAAAACACTCACTGAAGATTATGATTATGTC
  ATCAAGAATAAATCAGATATCGTTAAGAAATACAACGAAGTCTTTACAGATATCCAATCT
  AAACAGTAA
  60
  120
  180
  240
  300
  360
  369
  

⊟Protein

⊟General

• locus tag: SPG_0229
• symbol: SPG_0229
• description: iron ABC transporter, iron-binding protein
• length: 122
• theoretical pI: 9.75793
• theoretical MW: 13702.7
• GRAVY: -0.504098

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 61.8)
  and 5 more
  Metabolism Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 30.5)
  2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 28.8)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter substrate-binding protein, CPR_0540 family (TIGR03850; HMM-score: 18)
  Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 16.6)
  Metabolism Transport and binding proteins Other thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein (TIGR01276; HMM-score: 14.6)
• TheSEED  :
  • Ferric iron ABC transporter, iron-binding protein
  Iron acquisition and metabolism Iron acquisition and metabolism - no subcategory Iron acquisition in Streptococcus  Ferric iron ABC transporter, iron-binding protein
• PFAM:
  PBP (CL0177) SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 50.1)
  and 4 more
  SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 39.6)
  SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 35.4)
  SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 22.5)
  no clan defined DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 12.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.1599
  • Cytoplasmic Membrane Score: 0.2515
  • Cell wall & surface Score: 0.0032
  • Extracellular Score: 0.5854
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005231
  • TAT(Tat/SPI): 0.000445
  • LIPO(Sec/SPII): 0.000711
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: ACF55595 NCBI
• UniProt:

⊟Protein sequence

• MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAKNMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: pitB < SPG_0229

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications