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serotype 4
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EF3030
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70585
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BVJ1JL
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CGSP14
serotype 14
G54
serotype 19F
HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
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INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
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R6
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SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_1406 [new locus tag: SPG_RS07015 ]
  • pan locus tag?: PNEUPAN002806000
  • symbol: pgdA
  • pan gene symbol?: pgdA
  • synonym:
  • product: peptidoglycan GlcNAc deacetylase (pgdA)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_1406 [new locus tag: SPG_RS07015 ]
  • symbol: pgdA
  • product: peptidoglycan GlcNAc deacetylase (pgdA)
  • replicon: chromosome
  • strand: -
  • coordinates: 1361080..1362417
  • length: 1338
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    TTGGCTTTGATTGGTATTTTAGCAATTTCTATTTGCCTATTAGGCGGATTTATTGCTTTT
    AAGATCTACCAGCAAAAAAGTTTTGAGCAAAAGATTGAATCGCTCAAAAAAGAGAAAGAT
    GATCAATTGAGTGAGGGAAATCAGAAGGAGCATTTTCGTCAGGGGCAAGCCGAAGTGATT
    GCCTATTATCCTCTCCAAGGGGAGAAAGTGATTTCCTCTGTTAGGGAGCTGATAAATCAA
    GATGTTAAGGACAAGCTAGAAAGTAAGGACAATCTTGTTTTCTACTATACAGAGCAAGAA
    GAGTCAGGTTTAAAGGGAGTCGTTAATCGTAATGTGACCAAACAAATCTATGATTTAGTT
    GCTTTTAAGATTGAAGAGACTGAAAAGACCAGTCTAGGAAAGGTTCACTTAACAGAAGAT
    GGGCAACCTTTTACACTTGACCAACTGTTTTCAGATGCTAGTAAGGCTAAGGAACAGCTG
    ATAAAAGAGTTGACCTCCTTCATAGAGGATAAAAAAATAGAGCAAGACCAGAGTGAGCAG
    ATTGTAAAAAACTTCTCTGACCAAGACTTGTCTGCATGGAATTTTGATTACAAGGATAGT
    CAGATTATCCTTTATCCAAGTCCTGTGGTTGAAAATTTAGAAGAGATAGCCTTGCCAGTA
    TCTGCTTTCTTTGATGTTATCCAATCTTCGTACTTACTCGAAAAAGATGCGGCCTTGTAC
    CAATCTTACTTTGATAAGAAACATCAAAAAGTTGTCGCTCTAACCTTTGATGATGGTCCA
    AATCCAGCAACGACCCCGCAGGTATTAGAGACCCTAGCTAAATATGATATTAAAGCGACT
    TTCTTTGTGCTTGGGAAAAATGTTTCTGGGAATGAGGACTTGGTGAAGAGGATAAAATCT
    GAAGGTCATGTTGTTGGAAACCATAGTTGGAGCCATCCGATTCTCTCGCAACTCTCTCTT
    GATGAAGCTAAAAAGCAGATTACTGATACTGAGGATGTGCTAACTAAAGTGCTGGGTTCT
    AGTTCTAAACTCATGCGTCCACCTTATGGTGCTATTACAGATGATATTCGCAATAGCTTG
    GATTTGAGCTTTATCATGTGGGATGTGGATAGTCTGGACTGGAAGAGTAAAAATNAAGCA
    TCTATTTTGACANAAATTCANCATCAAGTAGCTAACGGCTCTATCNTTTTGATGCATGAT
    ATTCACAGTCCGACAGTCAATGCCTTGCCAAGGNTCATTGAGTATTTGAAAAATCAAGGT
    TATACCTTTGTGACCATACCAGAGATGCTCAATACTCGCCTAAAAGCTCATGAGCTGTAT
    TATAGTCGTGATGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1338

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_1406 [new locus tag: SPG_RS07015 ]
  • symbol: PgdA
  • description: peptidoglycan GlcNAc deacetylase (pgdA)
  • length: 445
  • theoretical pI: 4.86711
  • theoretical MW: 50022.3
  • GRAVY: -0.385455

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination polysaccharide deacetylase family sporulation protein PdaB (TIGR02764; HMM-score: 168.4)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan delta-lactam-biosynthetic de-N-acetylase (TIGR02884; EC 3.5.-.-; HMM-score: 136.5)
    Cellular processes Cellular processes Sporulation and germination delta-lactam-biosynthetic de-N-acetylase (TIGR02884; EC 3.5.-.-; HMM-score: 136.5)
    chitooligosaccharide deacetylase NodB (TIGR04243; EC 3.5.1.-; HMM-score: 134.8)
    and 3 more
    Cellular processes Cellular processes Sporulation and germination probable sporulation protein, polysaccharide deacetylase family (TIGR02873; HMM-score: 130.9)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides probable sporulation protein, polysaccharide deacetylase family (TIGR02873; HMM-score: 130.9)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides polysaccharide deacetylase family protein, PEP-CTERM locus subfamily (TIGR03006; HMM-score: 44.1)
  • TheSEED  :
    • Peptidoglycan N-acetylglucosamine deacetylase (EC 3.5.1.-)
    Cell Wall and Capsule Capsular and extracellular polysacchrides Polysaccharide deacetylases  Peptidoglycan N-acetylglucosamine deacetylase (EC 3.5.1.-)
  • PFAM:
    no clan defined PgdA_N; Peptidoglycan GlcNAc deacetylase N-terminal domain (PF18627; HMM-score: 284.8)
    and 5 more
    GH_CE (CL0158) Polysacc_deac_1; Polysaccharide deacetylase (PF01522; HMM-score: 122.6)
    Glyco_hydro_57; Glycosyl hydrolase family 57 (PF03065; HMM-score: 15.9)
    no clan defined FAM165; FAM165 family (PF14981; HMM-score: 13.8)
    GutM; Glucitol operon activator protein (GutM) (PF06923; HMM-score: 12.6)
    DUF2681; Protein of unknown function (DUF2681) (PF10883; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.162608
    • TAT(Tat/SPI): 0.003924
    • LIPO(Sec/SPII): 0.062275
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55764 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNXASILTXIXHQVANGSIXLMHDIHSPTVNALPRXIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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