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TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_1874
  • pan locus tag?:
  • symbol: SPG_1874
  • pan gene symbol?: —
  • synonym:
  • product: rRNA/tRNA methylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_1874
  • symbol: SPG_1874
  • product: rRNA/tRNA methylase
  • replicon: chromosome
  • strand: -
  • coordinates: 1789201..1789461
  • length: 261
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (1789201..1789461) NCBI
  • BioCyc:
  • MicrobesOnline: 5757141 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGACTAGTCAAGCGCTTNTTGACGAAACTAAAAAGGTAGCTATCCCAGTGCTAGCAACA
    ACCCTATCTAAAGATTCTGTTGATTACAGAGAACTGCCTTCTATAGAAAATTTTGTACTA
    GTTATGGGAAATGAGGGTCAAGGAATTAGTCCCCTTATGGCTGAAAGTGCAGACCAGTTG
    GTCCATATTAGCATGAAGGGGCAGGCCGAGAGTTTGAATGTTGCAGTTGCAGCCGGTATT
    TTAATNTTCCATTTAAGCTAA
    60
    120
    180
    240
    261

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_1874
  • symbol: SPG_1874
  • description: rRNA/tRNA methylase
  • length: 86
  • theoretical pI: 4.41692
  • theoretical MW: 8928.21
  • GRAVY: 0.230952

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification RNA methyltransferase, TrmH family, group 3 (TIGR00186; HMM-score: 62.9)
    and 3 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (cytidine(34)-2'-O)-methyltransferase (TIGR00185; EC 2.1.1.207; HMM-score: 22.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification RNA methyltransferase, TrmH family, group 1 (TIGR00050; EC 2.1.1.-; HMM-score: 17.3)
    UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03992; EC 2.3.1.157,2.7.7.23; HMM-score: 12.2)
  • TheSEED  :
    • FIG011178: rRNA methylase
  • PFAM:
    SPOUT (CL0098) SpoU_methylase; SpoU rRNA Methylase family (PF00588; HMM-score: 64.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9966
    • Cytoplasmic Membrane Score: 0.0009
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0023
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007536
    • TAT(Tat/SPI): 0.000564
    • LIPO(Sec/SPII): 0.00329
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55230 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTSQALXDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESADQLVHISMKGQAESLNVAVAAGILXFHLS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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