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serotype 19A
Hu17
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INV200
serotype 14
JJA
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MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
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OXC141
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SP49
serotype 19A
SPN032672
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SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS01725 [old locus tag: SPG_0340 ]
  • pan locus tag?: PNEUPAN001209000
  • symbol: mapZ
  • pan gene symbol?: mapZ
  • synonym:
  • product: cell division site-positioning protein MapZ

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS01725 [old locus tag: SPG_0340 ]
  • symbol: mapZ
  • product: cell division site-positioning protein MapZ
  • replicon: chromosome
  • strand: +
  • coordinates: 333205..334599
  • length: 1395
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGAGTAAAAAAAGACGAAATCGTCATAAAAAAGAAGGTCAAGAACCGCAATTTGATTTT
    GATGAAGCAAAAGAGCTAACAGTTGGTCAAGCTATTCGTAAAAATGAAGAAGTGGAAGCA
    GGAGTCTTGCCTGAGGATTCCATTTTGGACAAGTATGTTAAGCAACACAGAGATGAAATT
    GAGGCGGATAAGTTTGCGACTCGTCAATACAAAAAAGAGGAGTTCGTTGAAACTCAGAGT
    CTGGATGATTTAATTCAAGAGATGCGTGAGGCTGTAGAGAAGTCAGAAGCTTCTTCGGAG
    GAAGTTCCATCTTCTGAAGACATCTTACTACCCTTGCCTCTGGACGATGAGGAGCAAGGC
    TTGGATCCTCTATTGCTAGATGATGAAAATCCAACAGAAATGACTGAAGAAGTGGAAGAG
    GAGCAAAACCTTTCTCGTCTGGATCAAGAGGACTCAGAAAAGAAAAGTAAAAAAGGCTTT
    ATTTTGACCGTTTTGGCGCTTGTATCAGTAATTATTTGTGTCAGTGCTTATTATGTCTAC
    CGTCAAGTGGCTCGTTCGACCAAGGAAATTGAAACTTCTCAATCAACTACAGCCAATCAA
    TCGGATGTGGATGATTTTAATACACTTTATGACGCCTTTTACACAGATAGCAATAAAACG
    GCTTTGAAAAATAGCCAGTTTGATAAACTGAATCAACTCAAGACTTTACTTGATAAGCTG
    GAAGGTAGTCGTGAACATACGCTTGCCAAATCTAAATATGATAGTCTAGCAACGCAAATC
    AAGGCTATTCAAGATGTCAATGCTCAATTTGAGAAACCAGCTATTGTGGATGGTGTGTTG
    GATACCAATGCCAAAGCCAAATCGGATGCTAAATTTACGGATATTAAAACTGGAAATACG
    GAGCTTGATAAAGTGCTAGATAAGGCTATCAGTCTTGGTAAGAGCCAGCAAACAAGTACT
    TCTAGCTCAAGTTCAAGTCAAACTAGCAGCTCAAGTTCAAGTCAAGCAAGTTCAAATACG
    ACTAGTGAGCCAAAACCAAGTAGTTCAAATGAGACTAGAAGTAGTCGCAGTGAAGTCAAT
    ATGGGTCTCTCGAGTGCAGGGGTTGCTGTTCAAAGAAGTGCCAGTCGTGTTGCCTATAAT
    CAGTCTGCTATTGATGATAGTAATAACTCTGCCTGGGATTTTGCGGATGGTGTTTTGGAA
    CAAATTCTAGCAACTTCACGTTCACGTGGCTATATCACTGGAGACCAATATATCCTTGAA
    CGTGTCAATATCGTTAACGGCAATGGTTATTACAACCTCTATAAGCCAGATGGAACCTAT
    CTCTTTACCCTTAACTGTAAGACAGGATATTTTGTCGGAAATGGCGCTGGTCATGCGGAT
    GACTTGGACTACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1395

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_RS01725 [old locus tag: SPG_0340 ]
  • symbol: MapZ
  • description: cell division site-positioning protein MapZ
  • length: 464
  • theoretical pI: 4.39322
  • theoretical MW: 51555.1
  • GRAVY: -0.767672

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SPG_0340
  • PFAM:
    no clan defined MapZ_EC1; MapZ extracellular domain 1 (PF18041; HMM-score: 113.5)
    MapZ_C2; MapZ extracellular C-terminal domain 2 (PF18708; HMM-score: 106.4)
    and 8 more
    DUF6550; Family of unknown function (DUF6550) (PF20187; HMM-score: 17.5)
    TPR (CL0020) DUF6377; Domain of unknown function (DUF6377) (PF19904; HMM-score: 16)
    no clan defined Otopetrin; Otopetrin (PF03189; HMM-score: 13.7)
    RNase_H (CL0219) DDE_Tnp_IS240; DDE domain (PF13610; HMM-score: 13)
    HTH (CL0123) Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 12.9)
    no clan defined Orf78; Orf78 (ac78) (PF06024; HMM-score: 12.5)
    DUF3169; Protein of unknown function (DUF3169) (PF11368; HMM-score: 11.1)
    Vpu; Vpu protein (PF00558; HMM-score: 8.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9843
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0152
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005693
    • TAT(Tat/SPI): 0.000721
    • LIPO(Sec/SPII): 0.000826
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000039270 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLPEDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEVPSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGFILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSNKTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIVDGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSSQASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGHADDLDY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Aurore Fleurie, Christian Lesterlin, Sylvie Manuse, Chao Zhao, Caroline Cluzel, Jean-Pierre Lavergne, Mirita Franz-Wachtel, Boris Macek, Christophe Combet, Erkin Kuru, Michael S VanNieuwenhze, Yves V Brun, David Sherratt, Christophe Grangeasse
MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae.
Nature: 2014, 516(7530);259-262
[PubMed:25470041] [WorldCat.org] [DOI] (I p)

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