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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS12055
  • pan locus tag?: PNEUPAN000640000
  • symbol: SPG_RS12055
  • pan gene symbol?: —
  • synonym:
  • product: IS3 family transposase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS12055
  • symbol: SPG_RS12055
  • product: IS3 family transposase
  • replicon: chromosome
  • strand: +
  • coordinates: join(2024874..2025315,2025315..2026222)
  • length: 1350
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_011072 join(2024874..2025315,2025315..2026222) NCBI
  • BioCyc: SPG_RS12055 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAAATTAACTTATGATGATAAAGTTCAGATCTATGAACTAAGAAAGCAAGGATATAGC
    TTAGAGAAGCTTTCAAATAAATTTGGGATAAATAATTCTAATCTTAGGTATATGATTAAA
    TGGATTGATCGTTACGGAATAGAGTTCGGCAAAAAAGGAAAAAATCGTTACTATTCTCCT
    GATTTAAAACAAGAAATGATTAATAAAGTCTTACATGAAGGCTGGACTAAAGATAGAGTT
    TCTCTTGAATACGGTCTCCCAAGTCGTACGATACTTCTTAACTGGCTAGCACAATACAGG
    AAAAACGGGTATACTATTGTTGAGAAACCAAGAGGGAGAGTACCTAAAATGGGACGTAAG
    CCAAAAACGAGACCTGAAGAGAGGACAGAATTAGAACGTCTTCAAGCAGAAAATGAGTAC
    CTGAGAGCGGAGAATGCCATCCCTAAAAAAGTTAAGAGAACTCCGATTGAAGGAGGAAAA
    AGAGAAAGAAGAAAGACAGAAATTGTTCAAGAATTAATGACTGAGTTTTCGTTAGTTCTT
    CTTCTAAAAGCCATTAAACTAGCTCGTTGGACCTACTACTATCACTTGAAACAGCTAGAC
    AAAACAGATAAGGACCAAGAGCTTAAAGCTGAAATTCAATCCATCTTTATCGAACACAAG
    GGAAATTATGCTTATCGTCGGATTTATTTAGAACTAAGAAATCGTGGTTATCTGGTAAAT
    CATAAAAGAGTTCAAGGCTTGATAAAAGTACTCAATTTACAAGCTAAAATGCGACAGAAA
    CGAAAATATTCTTCTCATAAAGGAGACGTTGGCAAGAAGGCAGAGAATCTCATTCAAGGC
    CAATTTGAAGGCTCTAAAACAATGGAAAAGTGCTACACAGATGTGACAGAATTTGCCATT
    CCAGCAAGTACTCAAAAGCTTTACTTATCACCAGTTTTAGATGGCTTTAACAGCGAAATT
    ATCGCCTATAATCTTTCAACTTCACCCAATTTAGAACAAGTACAAACAATGTTGGAACAG
    TCATTCACAGAGAAGCACTACGAGAATACGATTCTCCATAGTGACCAAGGCTGGCAATAT
    CAACACGATTCTTATCATCGGTTTCTTGAGGGTAAGGGAATTCAAGCATCCATTTCACGT
    AAGGGTAACAGCCCAGACAATGGTATGATGGAGTCTTTCTTTGGGATTTTGAAATCGGAA
    ATGTTTTATGGCTATGAGAAAACATTTAAATCACTTAATCGATTGGAACAAGCTATTGTA
    GACTATATTGATTACTACAACAATAAACGAATTAAGGTAAAACTAAAAGGACTTAGCCCT
    GTGCAATACAGAACTAAATCCTTCGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1350

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_RS12055
  • symbol: SPG_RS12055
  • description: IS3 family transposase
  • length: 449
  • theoretical pI: 10.183
  • theoretical MW: 53048.5
  • GRAVY: -0.836971

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    RNase_H (CL0219) rve_2; Integrase core domain (PF13333; HMM-score: 81.7)
    and 14 more
    rve; Integrase core domain (PF00665; HMM-score: 59.6)
    HTH (CL0123) HTH_21; HTH-like domain (PF13276; HMM-score: 56.9)
    RNase_H (CL0219) rve_3; Integrase core domain (PF13683; HMM-score: 43)
    HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 20.9)
    HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 20.5)
    HTH_Tnp_1; Transposase (PF01527; HMM-score: 19.3)
    HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 19)
    MerR_1; MerR HTH family regulatory protein (PF13411; HMM-score: 17.8)
    HTH_35; Winged helix-turn-helix DNA-binding (PF13693; HMM-score: 15.6)
    HTH_32; Homeodomain-like domain (PF13565; HMM-score: 14.4)
    Bot1p; Eukaryotic mitochondrial regulator protein (PF12298; HMM-score: 14.3)
    LZ_Tnp_IS481; leucine-zipper of insertion element IS481 (PF13011; HMM-score: 13.9)
    HTH_39; Helix-turn-helix domain (PF14090; HMM-score: 12.3)
    no clan defined Endotoxin_N; delta endotoxin, N-terminal domain (PF03945; HMM-score: 8.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9614
    • Cytoplasmic Membrane Score: 0.0011
    • Cell wall & surface Score: 0.0222
    • Extracellular Score: 0.0154
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.027713
    • TAT(Tat/SPI): 0.002192
    • LIPO(Sec/SPII): 0.002181
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_128887631 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKWIDRYGIEFGKKGKNRYYSPDLKQEMINKVLHEGWTKDRVSLEYGLPSRTILLNWLAQYRKNGYTIVEKPRGRVPKMGRKPKTRPEERTELERLQAENEYLRAENAIPKKVKRTPIEGGKRERRKTEIVQELMTEFSLVLLLKAIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLIKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQSFTEKHYENTILHSDQGWQYQHDSYHRFLEGKGIQASISRKGNSPDNGMMESFFGILKSEMFYGYEKTFKSLNRLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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