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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0052 [new locus tag: SPH_RS00245 ]
  • pan locus tag?: PNEUPAN000021000
  • symbol: SPH_0052
  • pan gene symbol?: —
  • synonym:
  • product: conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0052 [new locus tag: SPH_RS00245 ]
  • symbol: SPH_0052
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 38476..39729
  • length: 1254
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAAACACTAGTCGAATTGATGGAAGAACGACAAAAACATGCAGATGAGTTATCTGAG
    ATCAAATTTAAAAAAGCTTCAATCGAAGAGAAATTGGAGTCAGCAACTATTGGAGAAGAA
    GAACTTGCACAGTTGAAATCGGATGCAGAAGGATTGGTATCCAAAGCAGATGAACTCAAG
    AACACAATTTCTAAGTTAGATGTTGAGATTGAAGAAAAACAAGACAATCTCAATAAAGCT
    GCTAAATCTATCAAGGAAGTACAGAAAGGCAAGATACAAATGGAATACTTAAAAACAAAA
    GAAGCTGCACTTGATTTCGCTCGAATCCTTATGGATAATGAAGGAAGCTCAAACAGTGCC
    CGTAAAGCGTGGGAAGCAAATCTGGTTGAAAAAGGTGTAACTGATGTTAACAAAATCTTA
    CCTGAACCAGTATTGATTGCAATCCAAAATGCATTTAATGATTACGATGGTATCCTGAAC
    CATGTAACCAAAGATCCTCGTTATGCAGTACGTGTTGCGCTTCAAACGCAACAAGCAAAA
    GCTAAAGGCCATCAAAATGGCAAAACAAAGAAAGATGAATCTTTTGTATTTATCGATTAT
    ACAATCAACTCTGCAGCTGTCTACATCAAGTACAGTTTTGAGTATGCTGACTTGAAGAAG
    GATACAACAGGTGCTTACTTCAACTATGTGATGAATGAACTAGCACAAGGCTTCATCCGT
    GCAGTTGAACGTGCTGTTGTTATCGGAGATGGTAAAAATAGTGATGATGATGACAAAATC
    ACTGAAATTAAATCTATCGCAGAAGAAACACTTGCTCAACTATTTGATACACAAGAAATC
    AGTGTTGACGGGGAATTTGACAGTACTGTTTTAGAAAACCTCGTCAAAGGGATTGATAAA
    CTTGCTGCAAATACAACTCCAATTTTGGTAACTTCAAAAACCATTGCTCGTAAACTTAAA
    ATGGTTAAGGATGGCGAAAAACGCTACATTGACCCACAACCATTCGCACCAATTTCACAA
    ACAGGGAATGTCATTGCTGGTTACCAAGTATATGTCTATGACTGGATGGAAGATGCGACT
    AACCCAATTATCGCATTTGCTGACAAGGCTTATAAGATGATTGGTGATGATGTTTCTGCT
    GATCGCTTTGAAGATTATGATGTAACGATGAATCGCCGTCATATCGAACTTGCTAGCGTG
    CTTGGTGGCCGACTTGGTCAGTACAAATCAGCTGTGAAATTCACAAAAGGTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1254

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_0052 [new locus tag: SPH_RS00245 ]
  • symbol: SPH_0052
  • description: conserved hypothetical protein
  • length: 417
  • theoretical pI: 4.84896
  • theoretical MW: 46704.5
  • GRAVY: -0.473141

⊟Function[edit | edit source]

  • TIGRFAM:
    Hypothetical proteins Conserved sensor histidine kinase inhibitor, KipI family (TIGR00370; HMM-score: 12.3)
    SH3 domain protein (TIGR04211; HMM-score: 11.5)
    flagellar export protein FliJ (TIGR02473; HMM-score: 11.4)
  • TheSEED  :
    • conserved domain protein
  • PFAM:
    Phage-coat (CL0373) Phage_capsid; Phage capsid family (PF05065; HMM-score: 47.9)
    and 11 more
    BCLiA (CL0551) ATG14; Vacuolar sorting 38 and autophagy-related subunit 14 (PF10186; HMM-score: 17.2)
    no clan defined DUF1465; Protein of unknown function (DUF1465) (PF07323; HMM-score: 16)
    zf-C4H2; Zinc finger-containing protein (PF10146; HMM-score: 14)
    DegQ; DegQ (SacQ) family (PF08181; HMM-score: 13.6)
    SHE3; SWI5-dependent HO expression protein 3 (PF17078; HMM-score: 12.9)
    Gal_mutarotase (CL0103) Bgal_small_N; Beta galactosidase small chain (PF02929; HMM-score: 11.9)
    NADP_Rossmann (CL0063) Glyco_hydro_4; Family 4 glycosyl hydrolase (PF02056; HMM-score: 10.1)
    no clan defined Baculo_p24; Baculovirus P24 capsid protein (PF05073; HMM-score: 9.3)
    DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 8.5)
    FlaC_arch; Flagella accessory protein C (FlaC) (PF05377; HMM-score: 8.3)
    FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 6.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.3942
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0034
    • Extracellular Score: 0.6021
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002777
    • TAT(Tat/SPI): 0.000417
    • LIPO(Sec/SPII): 0.000417
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKTLVELMEERQKHADELSEIKFKKASIEEKLESATIGEEELAQLKSDAEGLVSKADELKNTISKLDVEIEEKQDNLNKAAKSIKEVQKGKIQMEYLKTKEAALDFARILMDNEGSSNSARKAWEANLVEKGVTDVNKILPEPVLIAIQNAFNDYDGILNHVTKDPRYAVRVALQTQQAKAKGHQNGKTKKDESFVFIDYTINSAAVYIKYSFEYADLKKDTTGAYFNYVMNELAQGFIRAVERAVVIGDGKNSDDDDKITEIKSIAEETLAQLFDTQEISVDGEFDSTVLENLVKGIDKLAANTTPILVTSKTIARKLKMVKDGEKRYIDPQPFAPISQTGNVIAGYQVYVYDWMEDATNPIIAFADKAYKMIGDDVSADRFEDYDVTMNRRHIELASVLGGRLGQYKSAVKFTKG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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