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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0215 [new locus tag: SPH_RS01035 ]
  • pan locus tag?: PNEUPAN000790000
  • symbol: argG
  • pan gene symbol?: argG
  • synonym:
  • product: argininosuccinate synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0215 [new locus tag: SPH_RS01035 ]
  • symbol: argG
  • product: argininosuccinate synthase
  • replicon: chromosome
  • strand: +
  • coordinates: 188464..189660
  • length: 1197
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAGTAAAGAAAAAGTAATTTTGGCCTATTCTGGCGGTTTGGACACATCAGTTGCTATT
    ACCTGGTTAAAGAAAGACTATGATGTTGTTTCAGTTTGTATGGATGTGGGTGAAGGGAAA
    GACTTAGATTTCATCCATGATAAGGCTCTTAAGGTTGGGGCAGTAGAATCTTATGTCATT
    GATGTTAAGGACGAATTTGCTACAGATTATGTGCTAGTGGCTCATCAGTCACATGCCTAT
    TATGAACAAAAGTATCCCTTGGTATCTGCCTTGAGCCGCCCTCTGATTTCTAAAAAATTG
    GTTGAAATAGCGCATCAGATAGGAGCGACTACAATTGCTCATGGTTGTACCGGTAAGGGG
    AATGACCAAGTACGTTTTGAAGTATCGATTGCAGCCTTGGATCTCAATTTAAAAGTGATT
    GCTCCAGTTCGTGAATGGAAATGGTCTCGGGAGGAAGAAATTTATTATGCCAAGGAAAAT
    GGGGTGCCTGTTCCTGCTGACCTTGACAATCCCTACTCTGTCGACCAAAATCTTTGGGGA
    CGTGCCAATGAGTGTGGTATTTTGGAAAATCCATGGAATCAGGCTCCAGAAGAAGCCTTT
    GGCATCACAACTTCTCCAGAGCAAGCTCCAGATATGCCAGAATACATTGAGATTGAGTTT
    AGTGAAGGTGTTCCAGTTTCCCTCAATGGAGAAGTGTTAAAATTGGCAGATTTGATTCAA
    AAACTCAATGAAATAGCTGGAAAACATGGGGTTGGACGGATTGACCACGTGGAAAATCGC
    TTGGTTGGGATTAAATCAAGAGAAATCTATGAGTGTCCAGGTGCAGTGACCCTGCTGACA
    GCTCATAAGGAAATTGAGGACTTGACGCTTGTGAGAGAAGTGGCTCATTTTAAACCAATC
    ATAGAAAATGAATTATCAAATCTCATTTATAATGCTTTGTGGTTTAGTTCGGCTACACAA
    GCCTTGATTGCTTATATTAAAGAGACTCAAAAAGTTGTCAATGGGACTGCAAAAGTCAAA
    CTGTATAAGGGGAGCGCTCAGGTCGTGGCTCGGAAATCACCAAGTTCTCTTTACGATGAA
    AATTTGGCGACGTATACTAGTGCAGATACCTTTGACCAAGATGCGGCTGTTGGCTTTATT
    AAGTTATGGGGACTTCCAACCAAGGTTCATTCTGAGGTTCAAAAAAGCGCCAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1197

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_0215 [new locus tag: SPH_RS01035 ]
  • symbol: ArgG
  • description: argininosuccinate synthase
  • length: 398
  • theoretical pI: 4.93927
  • theoretical MW: 44080.8
  • GRAVY: -0.186683

⊟Function[edit | edit source]

  • reaction:
    EC 6.3.4.5?  ExPASy
    Argininosuccinate synthase ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Glutamate family argininosuccinate synthase (TIGR00032; EC 6.3.4.5; HMM-score: 534.7)
    and 1 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (TIGR00420; EC 2.1.1.61; HMM-score: 11.6)
  • TheSEED  :
    • Argininosuccinate synthase (EC 6.3.4.5)
    Miscellaneous Miscellaneous - no subcategory EC 6.3.4.- Ligases that form carbon-nitrogen bonds  Argininosuccinate synthase (EC 6.3.4.5)
  • PFAM:
    HUP (CL0039) Arginosuc_synth; Arginosuccinate synthase (PF00764; HMM-score: 567.6)
    and 3 more
    tRNA_Me_trans; tRNA methyl transferase HUP domain (PF03054; HMM-score: 13.8)
    QueC; Queuosine biosynthesis protein QueC (PF06508; HMM-score: 12.8)
    Diphthami_syn_2; Diphthamide synthase (PF01902; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006373
    • TAT(Tat/SPI): 0.000252
    • LIPO(Sec/SPII): 0.001263
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKEKVILAYSGGLDTSVAITWLKKDYDVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKENGVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEIEFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAVTLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVNGTAKVKLYKGSAQVVARKSPSSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSEVQKSAK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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