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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1253 [new locus tag: SPH_RS06065 ]
  • pan locus tag?: PNEUPAN000578000
  • symbol: SPH_1253
  • pan gene symbol?:
  • synonym:
  • product: conserved hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1253 [new locus tag: SPH_RS06065 ]
  • symbol: SPH_1253
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1164336..1164656
  • length: 321
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGAATGATTTACTCCTTATCCCAGTAATTTTTTTAGCAGTAGGAGGAATTCTCATTCTT
    TTATGGAGACTCTTTCTTATTGCCAGTGGACTTTTACTGATTGGTTTTGTCAGTTTTCTT
    ATTTTCGTAGAAGTCTATGGAATTTATCTGTTCTTTACAGAGACTGAACTTTACACGGAA
    GATTTGGCACAGAATGGATTATTTGGTTTTACGACTTTCTTTATCATCTTTAACCTTGCT
    TTGCTTGTCTTGGTAGGCTGGGTAGGGTATAAGTGGAAGAGGGATAATAACGTTTTAGCA
    AATCAACGCGATTTTTGGTGA
    60
    120
    180
    240
    300
    321

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_1253 [new locus tag: SPH_RS06065 ]
  • symbol: SPH_1253
  • description: conserved hypothetical protein
  • length: 106
  • theoretical pI: 4.26676
  • theoretical MW: 12261.5
  • GRAVY: 1.1066

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01118149: hypothetical protein
  • PFAM:
    no clan defined DUF5966; Family of unknown function (DUF5966) (PF19391; HMM-score: 88.8)
    and 6 more
    DUF2784; Protein of Unknown function (DUF2784) (PF10861; HMM-score: 10.4)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 9.1)
    DUF3951; Protein of unknown function (DUF3951) (PF13131; HMM-score: 8.3)
    DUF4059; Protein of unknown function (DUF4059) (PF13268; HMM-score: 7.3)
    YlaC; Inner membrane protein YlaC (PF10777; HMM-score: 6.9)
    Phage_holin_3_6; Putative Actinobacterial Holin-X, holin superfamily III (PF07332; HMM-score: 6.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9467
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0533
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000921
    • TAT(Tat/SPI): 0.000253
    • LIPO(Sec/SPII): 0.031699
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNDLLLIPVIFLAVGGILILLWRLFLIASGLLLIGFVSFLIFVEVYGIYLFFTETELYTEDLAQNGLFGFTTFFIIFNLALLVLVGWVGYKWKRDNNVLANQRDFW

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]