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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1292 [new locus tag: SPH_RS06255 ]
  • pan locus tag?: PNEUPAN002437000
  • symbol: dhaK1
  • pan gene symbol?: dhaK1
  • synonym:
  • product: dihydroxyacetone kinase, DhaK subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1292 [new locus tag: SPH_RS06255 ]
  • symbol: dhaK1
  • product: dihydroxyacetone kinase, DhaK subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1198655..1199644
  • length: 990
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAAAAATTATAAATGAACCGACACAAGTTGTTGATGAAATGTTGCAGGGATTGTCA
    TTCATGCATGATGACTTGGTTCAACGCTTAGATGGTTTTGATGTCATCGTTAGAAAGGCA
    GAAAAGACAGGAAAAGTTGGTCTCATTTCAGGTGGAGGATCAGGACATGAACCAAGTCAT
    GCTGGATTTGTAGGAGATGGAATGCTATCCGCTGCCATTTGTGGCGCAGTCTTTACCTCA
    CCTACTCCGGACCAAATTTTAGAAGCCATTAAGGCGGCTGATGAAGGTGCTGGAGTTTTC
    ATGGTCATCAAGAACTATTCTGGTGACATTATGAACTTTGAAATTGCACAAGAACTTGCT
    GAAATGGAAGGTATTGATGTAGCAAGTGTTGTAGTCGATGATGATATCGCTGTTGAAAAT
    AGTCTCTATACCCAAGGCCGTCGAGGTGTTGCAGGTACTATATTAGTCCATAAAATTTTG
    GGTGATGCGGCTCGTTCTGGTAAATCATTAGCTGAAATGAAGGACTTGGCCGACAAACTT
    GTCTTAGAAATTAAAACAATTGGCTTAGCTCTATCTGGCGCTACTGTTCCAGAAGTTGGG
    AAACCTGGATTTGTTCTAGAAGATGATGAATTTGAATATGGAGTTGGTATTCATGGTGAG
    CCAGGATATAAAAAAGAGAAAATGCAACCTTCAGCACAATTGGCCTCAGAATTGGTTGAA
    AAATTATCTGAAGGTTTCCAACTTAAAGCTGGAGAACGCTATGGCCTTCTCATCAATGGT
    TTAGGAAGCACTCCTCTTATGGAGCAATACGTATTTGCAAATGATGTGGCTAAATTACTC
    CATAAAAAAGGTGTTGACTTGGCGTTTAAGAAAATTGGAAACTATATGACATCAATTGAT
    ATGGCTGGCTTGTCATTAACATTGATTCGATTGGCAGATGATGAGTGGTTGGATGCTCTA
    AATGCACCTGTTACTACACCAGCTTGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    990

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1292 [new locus tag: SPH_RS06255 ]
  • symbol: DhaK1
  • description: dihydroxyacetone kinase, DhaK subunit
  • length: 329
  • theoretical pI: 4.45298
  • theoretical MW: 35155.1
  • GRAVY: 0.0337386

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.-?  ExPASy
  • TIGRFAM:
    dihydroxyacetone kinase, DhaK subunit (TIGR02363; EC 2.7.1.-; HMM-score: 499.1)
    probable dihydroxyacetone kinase DhaK1b subunit (TIGR02362; HMM-score: 399.4)
    and 1 more
    dihydroxyacetone kinase (TIGR02361; EC 2.7.1.29; HMM-score: 312.3)
  • TheSEED  :
    • Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
    Carbohydrates Central carbohydrate metabolism Dihydroxyacetone kinases  Phosphoenolpyruvate-dihydroxyacetone phosphotransferase (EC 2.7.1.121), dihydroxyacetone binding subunit DhaK
  • PFAM:
    EDD (CL0245) Dak1; Dak1 domain (PF02733; HMM-score: 394.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006144
    • TAT(Tat/SPI): 0.020916
    • LIPO(Sec/SPII): 0.000429
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKIINEPTQVVDEMLQGLSFMHDDLVQRLDGFDVIVRKAEKTGKVGLISGGGSGHEPSHAGFVGDGMLSAAICGAVFTSPTPDQILEAIKAADEGAGVFMVIKNYSGDIMNFEIAQELAEMEGIDVASVVVDDDIAVENSLYTQGRRGVAGTILVHKILGDAARSGKSLAEMKDLADKLVLEIKTIGLALSGATVPEVGKPGFVLEDDEFEYGVGIHGEPGYKKEKMQPSAQLASELVEKLSEGFQLKAGERYGLLINGLGSTPLMEQYVFANDVAKLLHKKGVDLAFKKIGNYMTSIDMAGLSLTLIRLADDEWLDALNAPVTTPAW

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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