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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1760 [new locus tag: SPH_RS08565 ]
  • pan locus tag?: PNEUPAN003066000
  • symbol: SPH_1760
  • pan gene symbol?: psaD
  • synonym: tpx
  • product: thiol peroxidase (Scavengase P20)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1760 [new locus tag: SPH_RS08565 ]
  • symbol: SPH_1760
  • product: thiol peroxidase (Scavengase P20)
  • replicon: chromosome
  • strand: +
  • coordinates: 1621056..1621547
  • length: 492
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGTAACTTTTCTCGGAAATCCTGTGAGCTTTACAGGTAAACAACTACAAGTCGGCGAC
    AAGGCGCTTGATTTTTCTCTTACTACAACAGATCTTTCTAAAAAATCTCTGGCTGATTTT
    GATGGCAAGAAAAAAGTCTTGAGTGTCGTTCCTTCTATCGATACAGGCATCTGCTCAACT
    CAAACACGTCGTTTTAATGAAGAATTGGCTGGACTGGACAACACGGTCGTATTGACTGTT
    TCAATGGACCTACCTTTTGCTCAAAAACGTTGGTGCGGTGCTGAAGGCCTTGACAATGCC
    ATTATGCTTTCAGACTACTTTGACCATTCTTTCGGGCGCGATTATGCCCTCTTGATCAAC
    GAATGGCACCTATTAGCACGCGCAGTCTTTGTCCTCGATACTGACAATACGATTCGCTAC
    GTTGAATACGTGGATAATATCAATTCTGAGCCAAACTTCGAAGCCGCAATTGCAGCTGCT
    AAAGCCCTATAG
    60
    120
    180
    240
    300
    360
    420
    480
    492

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1760 [new locus tag: SPH_RS08565 ]
  • symbol: SPH_1760
  • description: thiol peroxidase (Scavengase P20)
  • length: 163
  • theoretical pI: 4.51065
  • theoretical MW: 18019.3
  • GRAVY: -0.00736196

⊟Function[edit | edit source]

  • reaction:
    EC 1.11.1.-?  ExPASy
  • TIGRFAM:
    Cellular processes Cellular processes Detoxification peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 31.2)
    Cellular processes Cellular processes Adaptations to atypical conditions peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 31.2)
    and 1 more
    capsule biosynthesis phosphatase (TIGR01689; HMM-score: 12.7)
  • TheSEED  :
    • Thiol peroxidase, Tpx-type (EC 1.11.1.15)
    Sulfur Metabolism Sulfur Metabolism - no subcategory Thioredoxin-disulfide reductase  Thiol peroxidase, Tpx-type (EC 1.11.1.15)
  • PFAM:
    Thioredoxin (CL0172) Redoxin; Redoxin (PF08534; HMM-score: 84.2)
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 70.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6128
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.3866
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00516
    • TAT(Tat/SPI): 0.00045
    • LIPO(Sec/SPII): 0.00121
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKKKVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIMLSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAAKAL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Barak Hajaj, Hasan Yesilkaya, Rachel Benisty, Maayan David, Peter W Andrew, Nurith Porat
Thiol peroxidase is an important component of Streptococcus pneumoniae in oxygenated environments.
Infect Immun: 2012, 80(12);4333-43
[PubMed:23027531] [WorldCat.org] [DOI] (I p)

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