From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_2189 [new locus tag: SPH_RS10730 ]
  • pan locus tag?: PNEUPAN003621000
  • symbol: SPH_2189
  • pan gene symbol?: ulaC
  • synonym:
  • product: ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component)

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_2189 [new locus tag: SPH_RS10730 ]
  • symbol: SPH_2189
  • product: ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component)
  • replicon: chromosome
  • strand: -
  • coordinates: 2015199..2015684
  • length: 486
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATTTAAAACAAGCTTTAATTGACAATGACTCGATCCGACTAGGTTTAGAGGCTAAC
    GATTGGAAAGAAGCAGTCAAGGTAGCAGTAGATCCCTTGATTGAAAGTGGGGCAATTTTG
    CCAGAGTATTACGATGCTATCATTGAATCGACTGAAGAGTATGGGCCTTACTATATCTTG
    ATGCCAGGTATGGCTATGCCCCACGCTAGACCTGAAGCTGGTGTGCAAAGTGATGCCTTT
    TCATTAATTACCTTACAAAATCCTGTTGTATTTTCAGATGGGAAAGAGGTATCTGTTTTG
    TTGGCACTAGCAGCAACAAGTTCAAAAATTCACACAAGTGTAGCCATTCCACAAATTATT
    GCCCTGTTTGAATTAGAAGATTCTATTGCACGTTTACAGGCTTGCCAGACTAAAGAAGAT
    GTCTTGGCTATGATTGAAGAATCTAAGGATAGCCCTTATCTCGAAGGATTGGATTTGGAA
    AGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    486

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_2189 [new locus tag: SPH_RS10730 ]
  • symbol: SPH_2189
  • description: ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component)
  • length: 161
  • theoretical pI: 3.94075
  • theoretical MW: 17583.9
  • GRAVY: 0.078882

Function[edit | edit source]

  • reaction:
    EC 2.7.1.-?  ExPASy
  • TIGRFAM:
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 21)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 16.9)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 16.9)
  • TheSEED  :
    • Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
    Carbohydrates Monosaccharides L-ascorbate utilization (and related gene clusters)  Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
  • PFAM:
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 112.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004291
    • TAT(Tat/SPI): 0.000302
    • LIPO(Sec/SPII): 0.000535
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYYDAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLALAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLES

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]