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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_2344 [new locus tag: SPH_RS11485 ]
  • pan locus tag?: PNEUPAN003826000
  • symbol: SPH_2344
  • pan gene symbol?: pepV
  • synonym:
  • product: putative dipeptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_2344 [new locus tag: SPH_RS11485 ]
  • symbol: SPH_2344
  • product: putative dipeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 2152334..2153665
  • length: 1332
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAAAATAGATATAACAAATCAAGTTAAAGATGAATTTCTTATATCATTAAAAACCTTG
    ATTTCCTATCCTTCAGTACTCAATGAAGGAGAAAATGGAACACCTTTTGGACAAGCAATC
    CAAGATGTCCTAGAAAAAACTTTAGAGATTTGTCGAGACATAGGTTTCACTACCTATCTT
    GACCCTAAAGGTTATTACGGATATGCAGAAATCGGTCAGGGAGCAGAGCTTCTGGCCATT
    CTCTGTCATTTGGATGTTGTTCCATCAGGTGATGAAGCAGATTGGCAGACACCGCCATTT
    GAAGCAACTATCAAAGACGGCTGGGTATTCGGACGTGGTGTCCAAGATGATAAAGGCCCT
    TCGCTCGCAGCTCTCTATGCAGTAAAAAGCTTGCTGGACCAAGGTATTCAGTTCAAAAAG
    CGCGTACGCTTTATCTTTGGTACCGATGAGGAAACCCTCTGGCGCTGCATGGCACGCTAC
    AATACCATCGAAGAACAGGCCAGTATGGGCTTTGCACCTGACTCATCTTTTCCTCTGACC
    TATGCTGAAAAAGGGCTTCTACAGGTCAAACTTCATGGCCCGGGATCGGATCAACTAGAG
    CTTGAAGTAGGAGGCGCCTTTAACGTTGTACCAGACAAGGCCAACTACCAAGGTCTCCTC
    TATGAACAGGTTTGTAACGGTCTCAAAGAAGCTGGTTATGATTACCAAACCACTGAACAA
    ACCGTAACGGTTCTCGGAGTGCCAAAGCATGCTAAGGATGCTAGTCAAGGTATCAATGCT
    GTCATCCGACTAGCTACCATTCTTGCTCCTCTCCAAGAACACCCTGCTCTCAGTTTTCTT
    GCAACACAAGCAGGTCAAGACGGCACAGGAAGACAAATCTTTGGTGATATAGCAGATGAA
    CCTTCTGGTCACCTATCCTTTAATGTCGCAGGTCTCATGATCAATCATGAACGTTCTGAA
    ATCCGTATTGACATTCGGACTCCTGTCTTAGCTGACAAGGAAGAACTAGTAGAGTTGCTT
    ACAAGATGTGCACAAAACTACCAACTCCGCTACGAAGAGTTTGACTATCTAGCGCCTCTA
    TACGTCGCAAAAGACAGTAAACTCGTTAGCACACTGATGCAAATCTACCAAGAAAAGACT
    GGCGATAACAGTCCTGCTATTTCATCCGGTGGTGCCACTTTTGCTCGCACCATGCCAAAT
    TGTGTAGCCTTCGGCGCCTTATTCCCAGGAGCGAAGCAGACAGAACATCAGGCAAATGAA
    TGTGCCGTTCTAGAAGATTTGTACCGTGCTATGGATATTTATGCCGAAGCCGTCTATCGA
    CTTGCAACTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1332

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_2344 [new locus tag: SPH_RS11485 ]
  • symbol: SPH_2344
  • description: putative dipeptidase
  • length: 443
  • theoretical pI: 4.42878
  • theoretical MW: 48813.8
  • GRAVY: -0.196163

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.13.-?  ExPASy
  • TIGRFAM:
    putative dipeptidase (TIGR01887; EC 3.4.13.-; HMM-score: 524.6)
    and 12 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides dipeptidase PepV (TIGR01886; EC 3.4.13.-; HMM-score: 247.8)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 128)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 87.7)
    putative selenium metabolism hydrolase (TIGR03526; HMM-score: 65)
    Metabolism Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 58.1)
    N-acyl-L-amino-acid amidohydrolase (TIGR01880; EC 3.5.1.14; HMM-score: 49.9)
    N-acetyl-ornithine/N-acetyl-lysine deacetylase (TIGR01902; HMM-score: 42.1)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 24.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides amidohydrolase (TIGR01891; HMM-score: 16.4)
    amidase, hydantoinase/carbamoylase family (TIGR01879; EC 3.5.-.-; HMM-score: 14.3)
    Xaa-His dipeptidase (TIGR01893; EC 3.4.13.20; HMM-score: 14.3)
    peptidase T-like protein (TIGR01883; HMM-score: 13.2)
  • TheSEED  :
    • Xaa-His dipeptidase ArcT
  • PFAM:
    Peptidase_MH (CL0035) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 108.3)
    and 2 more
    Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 17.4)
    no clan defined M20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 16.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01633
    • TAT(Tat/SPI): 0.000968
    • LIPO(Sec/SPII): 0.001416
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVLEKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEATIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARYNTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQGLLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPALSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKEELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGATFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: ArgR2* (activation (repression)) regulon, AhrC* (activation (repression)) regulon, ArgR1* (activation (repression)) regulon, CcpA regulon
    ArgR2*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    AhrC*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    ArgR1*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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