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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 24-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_RS03730 [old locus tag: SPH_0768 ]
- pan locus tag?: PNEUPAN001589000
- symbol: SPH_RS03730
- pan gene symbol?: —
- synonym:
- product: cystathionine beta-lyase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_RS03730 [old locus tag: SPH_0768 ]
- symbol: SPH_RS03730
- product: cystathionine beta-lyase
- replicon: chromosome
- strand: +
- coordinates: 723178..723801
- length: 624
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010380 (723178..723801) NCBI
- BioCyc: SPH_RS03730 BioCyc
- MicrobesOnline: see SPH_0768
- PneumoBrowse for strain D39V: SPV_0585 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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601ATGACTGATATTAAAACTTTGGCTCTAAAGTATGGAGGTTATACAAGTCTGGACAAGGTC
TATCTGGATCAGCTTCTAGCTGGTAAAACAGAGCAGGAGCAGTTAACACTTATTACACCT
CCGCCAAGTGTTGTTAATGCCTACTTTGCAGAACTCTATCAGAAAAAAAGTCCTCAGGCT
GCGACGGATTATTTTGCAGAACTCAGTCAGGAACTGAATCTTTACAATACTGAGCCAAGT
TTCACCCTAGAAAATAAGCCTTTTATTCGGCTTAATCTGTCTGGTAAATCCTTTGGTTTT
TGTTATGAGAGTGACGGCTTTGGTCGGATTTTCTCTGAAAATGAGGAGAAAATCTCGGAT
GACTTGCTCTTTGAAATTGCGCAAATTTTCTCCCATCAATTAGTCTTTGAAGAGTCTGGT
AAGATTTACATGAAGCCTGTCAAGGACGAGGAAGTTGTCAGCCTAGAAAGTCTCACAGCT
TTGACTGATTTGGAAAGATTGGCTGATGGTCGAAAACGTCTCAAAGGCTACAGCCAAGAG
GATTTATTGCAAGAAGCTGCTGCTTTTTCTGGCAAACGCTATTTCCGATCGGAAAACCGC
ACAGCCATGTTATATATTGATTAA60
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624
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_RS03730 [old locus tag: SPH_0768 ]
- symbol: SPH_RS03730
- description: cystathionine beta-lyase
- length: 207
- theoretical pI: 4.46557
- theoretical MW: 23631.5
- GRAVY: -0.403865
⊟Function[edit | edit source]
- TIGRFAM: Energy metabolism Sugars galactose-1-phosphate uridylyltransferase (TIGR01239; EC 2.7.7.12; HMM-score: 19.4)and 1 moreglutamate decarboxylase (TIGR01788; EC 4.1.1.15; HMM-score: 11.4)
- TheSEED: see SPH_0768
- PFAM: HIT (CL0265) GalP_UDP_transf; Galactose-1-phosphate uridyl transferase, N-terminal domain (PF01087; HMM-score: 20.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.7548
- Cytoplasmic Membrane Score: 0.1981
- Cell wall & surface Score: 0.0007
- Extracellular Score: 0.0464
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.009395
- TAT(Tat/SPI): 0.000255
- LIPO(Sec/SPII): 0.001431
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSVVNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCYESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTALTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: miaA > hflX > SPH_RS03730 > rnz > SPH_RS03740
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0585 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]