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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-MAR-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS07875 [old locus tag: SPH_1624 ]
  • pan locus tag?: PNEUPAN002837000
  • symbol: atpB
  • pan gene symbol?: atpB
  • synonym:
  • product: F0F1 ATP synthase subunit A

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS07875 [old locus tag: SPH_1624 ]
  • symbol: atpB
  • product: F0F1 ATP synthase subunit A
  • replicon: chromosome
  • strand: -
  • coordinates: 1498307..1499023
  • length: 717
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_010380 (1498307..1499023) NCBI
  • BioCyc: SPH_RS07875 BioCyc
  • MicrobesOnline: see SPH_1624
  • PneumoBrowse for strain D39V: SPV_1340 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGAAGAAAGTATTAATCCAATCATCTCTATTGGTCCTGTTATCTTCAATCTGACTATG
    TTAGCCATGACTTTGTTGATTGTGGGAGTTATTTTTGTCTTTATTTATTGGGCAAGCCGC
    AATATGACCTTGAAACCCAAAGGAAAGCAAAATGTACTTGAGTATGTCTATGACTTTGTT
    ATTGGATTTACAGAACCTAACATTGGTTCGCGCTACATGAAAGATTACTCACTCTTTTTC
    CTTTGTTTATTCCTTTTCATGGTGATTGCCAATAACCTTGGCTTAATGACAAAGCTTCAA
    ACGATCGATGGGACTAACTGGTGGAGTTCGCCAACCGCTAATTTACAGTATGACTTAACC
    TTATCTTTTCTTGTCATTTTGTTGACACATATAGAAAGCGTTCGTCGTCGTGGATTTAAA
    AAAAGTATAAAATCTTTTATGAGTCCTGTTTTTGTCATACCGATGAATATCTTGGAAGAA
    TTTACAAACTTCTTATCTTTGGCTTTGCGGATTTTTGGGAATATCTTTGCAGGAGAGGTC
    ATGACGAGTTTGTTACTTCTTCTTTCCCACCAAGCTATTTATTGGTATCCAGTAGCCTTT
    GGAGCTAATTTGGCTTGGACTGCATTTTCTGTCTTTATTTCCTGCATCCAAGCTTATGTT
    TTTACTCTTTTGACATCTGTGTATTTAGGGAATAAGATTAATATTGAAGAGGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    717

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_RS07875 [old locus tag: SPH_1624 ]
  • symbol: AtpB
  • description: F0F1 ATP synthase subunit A
  • length: 238
  • theoretical pI: 7.40047
  • theoretical MW: 27208
  • GRAVY: 0.64874

Function[edit | edit source]

  • reaction:
    EC 7.1.2.2?  ExPASy
    non-specified enzyme name
  • TIGRFAM:
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F0, A subunit (TIGR01131; EC 3.6.3.14; HMM-score: 136.5)
    and 1 more
    alternate F1F0 ATPase, F0 subunit A (TIGR03306; EC 3.6.3.-; HMM-score: 58.6)
  • TheSEED: see SPH_1624
  • PFAM:
    no clan defined ATP-synt_A; ATP synthase A chain (PF00119; HMM-score: 161.3)
    and 3 more
    Pilin_N; Archaeal Type IV pilin, N-terminal (PF07790; HMM-score: 12.8)
    Sigma_reg_N; Sigma factor regulator N-terminal (PF13800; HMM-score: 6.8)
    ActD; Alternative complex III, ActD subunit (PF11821; HMM-score: 5.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00083
    • TAT(Tat/SPI): 0.000292
    • LIPO(Sec/SPII): 0.00131
  • predicted transmembrane helices (TMHMM): 5

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]