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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS11505 [old locus tag: SPH_2350 ]
  • pan locus tag?: PNEUPAN003842000
  • symbol: SPH_RS11505
  • pan gene symbol?: ybbK
  • synonym:
  • product: SPFH domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS11505 [old locus tag: SPH_2350 ]
  • symbol: SPH_RS11505
  • product: SPFH domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2155044..2155928
  • length: 885
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (2155044..2155928) NCBI
  • BioCyc: SPH_RS11505 BioCyc
  • MicrobesOnline: see SPH_2350
  • PneumoBrowse for strain D39V: SPV_1984 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTTTTCTGATTGTTTGTGTGCTCCTATTGGTGATAGTCACACTGAGTACAGTTTAT
    GTGGTTCGTCAGCAGTCGGTGGCGATTATTGAACGCTTTGGGAAATACCAAAAGGTTGCT
    AATAGCGGTATTCATATTCGCTTGCCTTTTGGGATTGACTCGATTGCAGCACGGATTCAG
    TTGCGCTTGTTGCAAAGTGATATTGTGGTTGAGACTAAGACCAAGGACAATGTGTTCGTT
    ATGATGAATGTAGCGACTCAGTACCGTGTCAACGAGCAGAGCGTGACAGATGCTTACTAT
    AAACTCATGCGTCCAGAATCTCAGATTAAATCTTATATCGAAGATGCCCTTCGCTCTTCT
    GTTCCAAAATTAACCTTGGATGAATTGTTTGAGAAAAAAGATGAGATTGCCCTTGAGGTT
    CAACACCAAGTAGCAGAAGAAATGACCACTTACGGCTACATTATCGTGAAAACCTTGATT
    ACCAAGGTCGAACCAGATGCAGAAGTGAAGCAATCCATGAATGAAATCAATGCGGCGCAA
    CGCAAGCGGGTCGCAGCACAAGAATTGGCGGAAGCAGACAAGATTAAAATCGTCACTGCA
    GCTGAAGCCGAAGCAGAAAAGGATCGCCTTCATGGTGTGGGGATTGCCCAACAACGTAAG
    GCGATTGTGGATGGATTGGCAGAGTCTATCACAGAACTCAAGGAAGCCAATGTTGGCATG
    ACAGAAGAACAAATCATGTCCATCCTCTTGACCAACCAGTATTTGGATACCTTGAATACC
    TTTGCCTCTAAAGGAAACCAAACCATCTTTTTACCAAATACGCCAAATGGTGTGGATGAT
    ATCCGTACACAAATATTGTCAGCCCTTCGCGCTGAGAAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    885

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS11505 [old locus tag: SPH_2350 ]
  • symbol: SPH_RS11505
  • description: SPFH domain-containing protein
  • length: 294
  • theoretical pI: 5.51085
  • theoretical MW: 33001.9
  • GRAVY: -0.0636054

⊟Function[edit | edit source]

  • TIGRFAM:
    HflK protein (TIGR01933; HMM-score: 63.5)
    and 2 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides HflC protein (TIGR01932; HMM-score: 47.1)
    Signal transduction Regulatory functions Protein interactions HflC protein (TIGR01932; HMM-score: 47.1)
  • TheSEED: see SPH_2350
  • PFAM:
    SPFH (CL0433) Band_7; SPFH domain / Band 7 family (PF01145; HMM-score: 103)
    and 3 more
    no clan defined SseB_C; SseB protein C-terminal domain (PF14581; HMM-score: 13.1)
    DUF1104; Protein of unknown function (DUF1104) (PF06518; HMM-score: 12.3)
    SPFH (CL0433) Band_7_1; SPFH domain-Band 7 family (PF13421; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0007
    • Cytoplasmic Membrane Score: 0.9545
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0446
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.241454
    • TAT(Tat/SPI): 0.001606
    • LIPO(Sec/SPII): 0.020392
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGIHIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKLMRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLITKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQRKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPNGVDDIRTQILSALRAEKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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