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Xen35
serotype 4
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serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_2211 [new locus tag: SPJ_RS10945 ]
  • pan locus tag?: PNEUPAN003854000
  • symbol: SPJ_2211
  • pan gene symbol?: glpF
  • synonym:
  • product: glycerol uptake facilitator protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_2211 [new locus tag: SPJ_RS10945 ]
  • symbol: SPJ_2211
  • product: glycerol uptake facilitator protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2061909..2062613
  • length: 705
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGATGAATGAATTATTTGGAGAATTTCTAGGGACTTTAATCCTGATTCTTCTAGGAAAT
    GGTGTTGTTGCAGGTGTGGTTCTTCCTAAAACCAAGAGCAATAGCTCAGGTTGGATTGTG
    ATTACTATGGGTTGGGGGATTGCAGTTGCGGTTGCAGTCTTTGTATCTGGCAAGCTCAGT
    CCAGCTCATTTAAATCCAGCTGTGACAGTTGGTGTAGCTTTAAAAGGTGACTTGCCTTGG
    GCTTCCGTTTTGCCTTATATCTTAGCCCAGTTCGCAGGGGCCATGCTGGGTCAGATTTTG
    GTTTGGTTGCAATTCAAACCTCACTATGAGGCAGAAGAAAATGCAGGCAATATCCTGGCA
    ACCTTCAGTACTGGACCAGCCATCAAGGATACTGTATCAAACTTGATTAGCGAAATCCTT
    GGAACCTTTGTTTTGGTGTTGACAATCTTTGCTTTGGGTCTTTACGATTTTCAGGCAGGT
    ATCGGAACCTTTGCAGTGGGAACTTTGATTGTCGGTATCGGTCTATCACTAGGTGGGACA
    ACAGGTTATGCCTTGAACCCAGCTCGTGACCTTGGACCTCGTATCATGCACAGCATCTTG
    CCAATTCCAAACAAGGGAGACGGAGACTGGTCTTACGCTTGGATTCCTGTTGTAGGCCCT
    GTTATCGGAGCAGCCTTGGCAGTGCTTGTATTCTCACTTTTCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    705

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_2211 [new locus tag: SPJ_RS10945 ]
  • symbol: SPJ_2211
  • description: glycerol uptake facilitator protein
  • length: 234
  • theoretical pI: 5.58167
  • theoretical MW: 24388.6
  • GRAVY: 0.859402

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate MIP family channel proteins (TIGR00861; HMM-score: 184.2)
  • TheSEED  :
    • Glycerol uptake facilitator protein
    Carbohydrates Central carbohydrate metabolism Dihydroxyacetone kinases  Glycerol uptake facilitator protein
    and 2 more
    Carbohydrates Sugar alcohols Glycerol and Glycerol-3-phosphate Uptake and Utilization  Glycerol uptake facilitator protein
    Stress Response Osmotic stress Osmoregulation  Glycerol uptake facilitator protein
  • PFAM:
    Aquaporin-like (CL0716) MIP; Major intrinsic protein (PF00230; HMM-score: 154)
    and 2 more
    no clan defined CobS; Cobalamin-5-phosphate synthase (PF02654; HMM-score: 14.6)
    DUF6594; Family of unknown function (DUF6594) (PF20237; HMM-score: 11.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.067089
    • TAT(Tat/SPI): 0.006562
    • LIPO(Sec/SPII): 0.034164
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMGWGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVWLQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAGIGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVVGPVIGAALAVLVFSLF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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