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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_RS09430 [old locus tag: SPJ_1901 ]
  • pan locus tag?: PNEUPAN000188000
  • symbol: SPJ_RS09430
  • pan gene symbol?: —
  • synonym:
  • product: XRE family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_RS09430 [old locus tag: SPJ_1901 ]
  • symbol: SPJ_RS09430
  • product: XRE family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 1782253..1783005
  • length: 753
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012466 (1782253..1783005) NCBI
  • BioCyc: SPJ_RS09430 BioCyc
  • MicrobesOnline: see SPJ_1901
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAATATACTAGGTAGCTCAATTAAAGAAGTAAGAAAATCCAAGAAATTAACTCAAAAA
    AAACTTGCCGAGCTGACAGGTTTTAAACAAAATACAATTTCTAACCATGAAAACGGAAAT
    AGACAGTTAGATGAAAAAGATATTAGAATATACGCTCAGGCTTTAGAAGTTTCTCCTCAA
    TATCTATTTGACCTAGCCAAACCTTCATCTATTGAAATTATCCCTACCACTTCCCCAATC
    CAAACCATCTACGACGAACTAGAACCACCTAGACAGGGCAAAGTCCTGAATTATGCAAAG
    AGGCAACTGAAAGAGCAGAGGAACGAAGAAGAAACGAAGATAAACGAAGTATCGGAGAAC
    ATCATCAGACTGGACGACTACAGACAGACTACTTACCGACGTGTTACTGGGGTTGTCTCT
    GCTGGTAGTGGTTCGATACAGGACGACGATTTAGATATGGAGGTTTCGTTCTATGAGGAT
    GAAATCCCAGACGACTACGACGCTATCGCTTATGTCGTCGGCAACTCTATGGAGCCAAAG
    ATAAAGAATGGTGACTATCTTTTTATAAAGAATACCCAACAGGTTGATTATAACACTATC
    GGCATCTTCCAAGTAGACGGCGCTAACTATGTTAAGAAACTGCGTCAGGGATATCTGGAA
    AGCTTGAATCCAGATTATGAGGATATACACCTAGACGAAAGCAACGACATCCGAACTATT
    GGGGAAGTTGTCAGTGTGTATAGGGAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    753

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_RS09430 [old locus tag: SPJ_1901 ]
  • symbol: SPJ_RS09430
  • description: XRE family transcriptional regulator
  • length: 250
  • theoretical pI: 4.5468
  • theoretical MW: 28744.8
  • GRAVY: -0.7532

⊟Function[edit | edit source]

  • TIGRFAM:
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 30.8)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 30.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 29.4)
    Signal transduction Regulatory functions DNA interactions repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 29.4)
    and 4 more
    signal peptidase I (TIGR02228; EC 3.4.21.89; HMM-score: 18.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal peptidase I (TIGR02227; EC 3.4.21.89; HMM-score: 17.5)
    Cellular processes Cellular processes Detoxification nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 13.7)
    Genetic information processing Protein fate Protein modification and repair nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 13.7)
  • TheSEED: see SPJ_1901
  • PFAM:
    Peptidase_SF (CL0299) Peptidase_S24; Peptidase S24-like (PF00717; HMM-score: 75.9)
    and 8 more
    HTH (CL0123) HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 48.5)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 45.4)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 31.9)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 20.7)
    HTH_37; Helix-turn-helix domain (PF13744; HMM-score: 20.3)
    YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 17)
    MqsA_antitoxin; Antitoxin component of bacterial toxin-antitoxin system, MqsA (PF15731; HMM-score: 14.7)
    HTH_25; Helix-turn-helix domain (PF13413; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9882
    • Cytoplasmic Membrane Score: 0.0019
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0097
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009504
    • TAT(Tat/SPI): 0.000493
    • LIPO(Sec/SPII): 0.001894
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNILGSSIKEVRKSKKLTQKKLAELTGFKQNTISNHENGNRQLDEKDIRIYAQALEVSPQYLFDLAKPSSIEIIPTTSPIQTIYDELEPPRQGKVLNYAKRQLKEQRNEEETKINEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQDDDLDMEVSFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKKLRQGYLESLNPDYEDIHLDESNDIRTIGEVVSVYREK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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