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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN032672
  • locus tag: SPN032672_RS08060
  • pan locus tag?: PNEUPAN001131000
  • symbol: SPN032672_RS08060
  • pan gene symbol?: pglA
  • synonym:
  • product: glycosyltransferase family 4 protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN032672_RS08060
  • symbol: SPN032672_RS08060
  • product: glycosyltransferase family 4 protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1498220..1499356
  • length: 1137
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021003 (1498220..1499356) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAATTTACAAAAGAAAAAAATTATGTTAATAACTAATCATGACGATGATATCTATTGT
    TTTCGAAAAGAAGTTATAGAGTCACTAGTTGAGTATGGGTATGAAGTGCTAGTGTCATGT
    CCTTATGGAGATAAGATAGAGTTGATGAAGTCTATTCAATTTGAGTATGAAGATATTACT
    ATTGATAGAAGAGGAATAAACCCTTTAAAAGATATTCGTCTATTTCTTAGTTATATAAGA
    TTATTGAGAAAATATAGACCGGATGTAGTCTTGACATATACCGTGAAACCAAATGTATAT
    GCTAGCCTAGCTGCAACAATTTTAGGAATAAAATATATAAATAACGTAACAGGTTTAGGT
    AGTGTCTTAACAATGGGTTCTTGTGTAAGAAGCCTGGTGTTATTACTGTTTAGAATTTCT
    TTTAGGAAATCAAATTGTGTTTTTTTTCAAAATGAATATAATATGAAAATGTTAAAAACT
    CTTGGCTTGATTTTGGGTGACTCTAAGCTGATACCTGGGTCAGGAGTGAACATTGAAAAG
    TATCCTGTGCAACAGTATCCAAATGGTGGAAATGGAATTCAAGGAGAAACAATCGTTTTT
    AATTTTATTGGTAGGATATTAAAAGAAAAAGGTATAGATACTTATCTGGCTGCTGCCCAA
    ATTATTAAGAGTCGATATCCCAAAACAGAGTTTAATATTATTGGCTTTATAGAACCGACA
    GAGAGTAATTATGAACTTAAAATTTGTGACTTAGAAAAAAAAGGAATCGTTTATTATTTG
    GGACAACAAAAAGATGTGATACCTCATATTACCCGTTCCCATGCAATTATCCATCCCAGT
    GTGTATGGTGAAGGAATGAGCAATGTATTACTAGAAAACGCTAGTTCAGGACGTGTTTTA
    ATTACGACAGATAATCCAGGTTGCAAAGAAATTGTTAAAGATAGAGAGACAGGCTATATA
    TTTCAAGGGGGAAATGTTGAGGAACTAGTCTCTATATTGGAAGTTTTTTTAGGTCTAGAA
    AATGAAAAACGAAAAGAGATGGGACTTCAAGGGAGAATGTATATAGAGCAATATTTTTCT
    CGTCAAATTATTATAGATGCTTATTTAGATAAAATAAAAGGAGCTTTAGATGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1137

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN032672_RS08060
  • symbol: SPN032672_RS08060
  • description: glycosyltransferase family 4 protein
  • length: 378
  • theoretical pI: 8.06712
  • theoretical MW: 43075.8
  • GRAVY: -0.0883598

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.-.-?  ExPASy
  • TIGRFAM:
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 69)
    and 10 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA (TIGR03999; EC 2.4.1.-; HMM-score: 37.9)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen synthase, Corynebacterium family (TIGR02149; HMM-score: 35)
    PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family (TIGR04063; EC 2.4.-.-; HMM-score: 34)
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03087; HMM-score: 33.3)
    D-inositol-3-phosphate glycosyltransferase (TIGR03449; EC 2.4.1.250; HMM-score: 30.5)
    glycosyltransferase, GG-Bacteroidales peptide system (TIGR04157; EC 2.4.1.-; HMM-score: 24)
    colanic acid biosynthesis glycosyltransferase WcaL (TIGR04005; EC 2.4.-.-; HMM-score: 22.2)
    putative glycosyltransferase, TIGR04348 family (TIGR04348; EC 2.4.1.-; HMM-score: 22)
    sucrose-phosphate synthase, putative, glycosyltransferase domain (TIGR02472; EC 2.4.1.14; HMM-score: 21.9)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen/starch synthase, ADP-glucose type (TIGR02095; EC 2.4.1.21; HMM-score: 10.2)
  • TheSEED:
  • PFAM:
    GT-B (CL0113) Glycos_transf_1; Glycosyl transferases group 1 (PF00534; HMM-score: 83.8)
    Glyco_trans_4_2; Glycosyl transferase 4-like (PF13477; HMM-score: 68.3)
    and 5 more
    Glyco_trans_1_4; Glycosyl transferases group 1 (PF13692; HMM-score: 61.8)
    Glyco_trans_1_2; Glycosyl transferases group 1 (PF13524; HMM-score: 24.8)
    Glyco_trans_4_4; Glycosyl transferase 4-like domain (PF13579; HMM-score: 20.5)
    Glyco_transf_4; Glycosyltransferase Family 4 (PF13439; HMM-score: 18.6)
    no clan defined PIG-L; GlcNAc-PI de-N-acetylase (PF02585; HMM-score: 12.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0536
    • Cytoplasmic Membrane Score: 0.8676
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0783
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005235
    • TAT(Tat/SPI): 0.000158
    • LIPO(Sec/SPII): 0.001229
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001053205 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGDKIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYASLAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKTLGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAAAQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAIIHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILEVFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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