PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 11-FEB-2025

⊟Summary

• organism: Streptococcus pneumoniae SPN032672
• locus tag: SPN032672_RS09115
• pan locus tag^?: PNEUPAN001472000
• symbol: SPN032672_RS09115
• pan gene symbol^?: paiA
• synonym:
• product: GNAT family N-acetyltransferase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPN032672_RS09115
• symbol: SPN032672_RS09115
• product: GNAT family N-acetyltransferase
• replicon: chromosome
• strand: +
• coordinates: 1698965..1699474
• length: 510
• essential: unknown other strains

⊟Accession numbers

• Location: NC_021003 (1698965..1699474) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0505 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  
  ATGATTAGAAAAGTAGAAATGGCAGATGTTGAGGTGTTGGCTAAAATTGCCAAACAAGCC
  TTTCGTGAAACCTTTGCGTATGATAATACGGAAGAGCAGTTACAGGAATACTTTGAAGAG
  GCTTATAGTCTGAAAACTTTGTCAACTGAGTTGGGAAATCCTGACTCTGAAACCTATTTC
  ATTATGCATGAGGAGGAGATAGCTGGTTTTCTCAAAGTCAACTGGGGAAGTGCTCAAACT
  GAGAGAGAATTAGAGGACGCTTTTGAAATTCAACGCCTCTATGTGCTACAAAAATTCCAA
  GGATTTGGACTAGGTAAGCAACTGTTTGAATTCGCACTTGAACTTGCTACAAAAAATAGT
  TTTTCTTGGGCTTGGCTAGGTGTTTGGGAGCATAATACAAAAGCTCAAGCGTTTTATAAC
  CGATATGGTTTTGAAAAATTTAGCCAACATCATTTTATGGTTGGTCAAAAAGTAGATACG
  GATTGGTTACTGAGAAAGAAATTAAGGTAA
  60
  120
  180
  240
  300
  360
  420
  480
  510
  

⊟Protein

⊟General

• locus tag: SPN032672_RS09115
• symbol: SPN032672_RS09115
• description: GNAT family N-acetyltransferase
• length: 169
• theoretical pI: 4.95345
• theoretical MW: 20035.5
• GRAVY: -0.498225

⊟Function

• reaction:
  EC 2.3.1.-?  ExPASy
• TIGRFAM:
  Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 44.3)
  and 4 more
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 23)
  UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 20.7)
  arginine and ornithine succinyltransferase subunits (TIGR03243; EC 2.3.1.-; HMM-score: 14.2)
  Metabolism Energy metabolism Amino acids and amines arginine N-succinyltransferase (TIGR03244; EC 2.3.1.109; HMM-score: 12.7)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  Acetyltrans (CL0257) Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 51)
  Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 48.8)
  Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 42.9)
  and 7 more
  FR47; FR47-like protein (PF08445; HMM-score: 27.3)
  AstA; Arginine N-succinyltransferase beta subunit (PF04958; HMM-score: 18.2)
  Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 17.8)
  Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 16.7)
  Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 16.5)
  Acetyltransf_16; GNAT acetyltransferase, Mec-17 (PF05301; HMM-score: 13.2)
  no clan defined Amelin; Ameloblastin precursor (Amelin) (PF05111; HMM-score: 10.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9997
  • Cytoplasmic Membrane Score: 0.0001
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0001
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005808
  • TAT(Tat/SPI): 0.000602
  • LIPO(Sec/SPII): 0.000699
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_000619941 NCBI
• UniProt:

⊟Protein sequence

• MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSLKTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGFGLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDTDWLLRKKLR

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_0505 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications