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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034156
  • locus tag: SPN034156_13500 [new locus tag: SPN034156_RS07545 ]
  • pan locus tag?: PNEUPAN001012000
  • symbol: SPN034156_13500
  • pan gene symbol?: relE1
  • synonym:
  • product: addiction module toxin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034156_13500 [new locus tag: SPN034156_RS07545 ]
  • symbol: SPN034156_13500
  • product: addiction module toxin
  • replicon: chromosome
  • strand: +
  • coordinates: 1387887..1388165
  • length: 279
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312045 (1387887..1388165) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0256 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    GTGCTTAAGATTCGTTATCATAAACAGTTTAAAAAAGATTTTAAGTTGGCTATGAAGCGT
    GGTTTGAAGGCAGAATTATTAGAAGAAGTTTTGAATTTTCTGGTTCAAGAAAAAGAACAT
    CCTGCCAGATATCGTGATCATTCATTGACGGCATCCAAGCATTTTCAAGGAGTTTGTGAA
    TGCCATACCCAGCCAGATTGGCTTTTGGTTTATAAAGTAGACAAGTCGGAATTGATTTTA
    AATTTGCTGAGGACAGGCAGTCACAGTGATTTATTTTAA
    60
    120
    180
    240
    279

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034156_13500 [new locus tag: SPN034156_RS07545 ]
  • symbol: SPN034156_13500
  • description: addiction module toxin
  • length: 92
  • theoretical pI: 9.55624
  • theoretical MW: 10939.7
  • GRAVY: -0.498913

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance addiction module toxin, RelE/StbE family (TIGR02385; HMM-score: 90.6)
    Genetic information processing Mobile and extrachromosomal element functions Other addiction module toxin, RelE/StbE family (TIGR02385; HMM-score: 90.6)
    and 1 more
    Cellular processes Cellular processes Adaptations to atypical conditions addiction module toxin component, YafQ family (TIGR00053; HMM-score: 71)
  • TheSEED  :
    • YafQ toxin protein
    Regulation and Cell signaling Programmed Cell Death and Toxin-antitoxin Systems Toxin-antitoxin systems (other than RelBE and MazEF)  YafQ toxin protein
  • PFAM:
    Plasmid-antitox (CL0136) YafQ_toxin; Bacterial toxin of type II toxin-antitoxin system, YafQ (PF15738; HMM-score: 96)
    and 1 more
    ParE_toxin; ParE toxin of type II toxin-antitoxin system, parDE (PF05016; HMM-score: 30)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9709
    • Cytoplasmic Membrane Score: 0.0011
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0275
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006284
    • TAT(Tat/SPI): 0.000504
    • LIPO(Sec/SPII): 0.000679
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP37019 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARYRDHSLTASKHFQGVCECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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