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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034156
  • locus tag: SPN034156_RS08975 [old locus tag: SPN034156_16170 ]
  • pan locus tag?: PNEUPAN001515000
  • symbol: SPN034156_RS08975
  • pan gene symbol?: nrd
  • synonym:
  • product: nitroreductase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034156_RS08975 [old locus tag: SPN034156_16170 ]
  • symbol: SPN034156_RS08975
  • product: nitroreductase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1671743..1672348
  • length: 606
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021006 (1671743..1672348) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0541 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGAAATTTCTTGAATTAAATAAAAAACGTCATGCGACCAAGCATTTTACTGATAAGCCT
    GTTGATCCCAAAGATGTGCGTACGGCTATCGAAATTGCAACCTTGGCGCCAAGCGCCCAC
    AACAGCCAGCCTTGGAAATTTGTGGTGGTACGTGAGAAAAATGCTGAACTGGCAAAGTTA
    GCTTATGGTTCCAATTTTGAACAGGTATCATCAGCACCTGTAACCATTGCCCTATTTACA
    GATACAGACCTTGCCAAACGCGCTCGTAAGATTGCCCGAGTTGGTGGTGCTAACAATTTC
    TCAGAAGAACAACTTCAATACTTCATGAAAAATTTGCCAGCTGAATTTGCACGCTACAAT
    GAACAACAAGTCAGCGACTACCTAGCACTCAATGCAGGTTTGGTTGCTATGAACTTGGTT
    CTCGCTCTTACAGACCAAGGAATTGGTTCCAATATTATCCTTGGTTTTGACAAATCAAAA
    GTTAATGAAGTTTTGGAAATCGAAGACCGTTTCCGCCCAGAACTCTTGATCACAGTGGGT
    TACACAGACGACAAATTGGAACCAAGCTACCGCTTGCCAGTAGATGAAATCATCGAAAAA
    AGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    606

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034156_RS08975 [old locus tag: SPN034156_16170 ]
  • symbol: SPN034156_RS08975
  • description: nitroreductase family protein
  • length: 201
  • theoretical pI: 6.81718
  • theoretical MW: 22683.8
  • GRAVY: -0.324876

⊟Function[edit | edit source]

  • reaction:
    EC 1.-.-.-?  ExPASy
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other F420 biosynthesis protein FbiB, C-terminal domain (TIGR03553; HMM-score: 52.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin 5,6-dimethylbenzimidazole synthase (TIGR02476; EC 1.14.99.40; HMM-score: 51.1)
    and 1 more
    SagB-type dehydrogenase domain (TIGR03605; HMM-score: 22.2)
  • TheSEED: see SPN034156_16170
  • PFAM:
    FMN-dep-NRtase (CL0529) Nitroreductase; Nitroreductase family (PF00881; HMM-score: 104.2)
    and 1 more
    TM1586_NiRdase; Putative TM nitroreductase (PF14512; HMM-score: 60.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9154
    • Cytoplasmic Membrane Score: 0.038
    • Cell wall & surface Score: 0.0012
    • Extracellular Score: 0.0453
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006886
    • TAT(Tat/SPI): 0.00061
    • LIPO(Sec/SPII): 0.001298
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000670162 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQPWKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSEEQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSKVNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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