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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034183
  • locus tag: SPN034183_10080 [new locus tag: SPN034183_RS05440 ]
  • pan locus tag?: PNEUPAN002247000
  • symbol: SPN034183_10080
  • pan gene symbol?: rluD3
  • synonym:
  • product: putative RNA pseudouridylate synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034183_10080 [new locus tag: SPN034183_RS05440 ]
  • symbol: SPN034183_10080
  • product: putative RNA pseudouridylate synthase
  • replicon: chromosome
  • strand: +
  • coordinates: 1013632..1014528
  • length: 897
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312043 (1013632..1014528) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0984 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGGTTTGAATTTATCGCAGATGAACATGTCAAGGTTAAGACCTTTTTAAAAAAGCAC
    GAGGTTTCTAAGGGATTGCTGGCTAAGATTAAGTTTCGAGGTGGAGCTATTCTGGTCAAT
    AATCAACCGCAAAATGCAACGTATCTATTGGACGTTGGAGACTACGTTACCATTTACATT
    CCCGCTGAGGAAGGCTTTGAAACCTTGGAGGCTATTGAGCATCCATTAGATATTCTCTAT
    GAGGATGACCACTTTCTAGTCTTGAATAAACCCTATGGAGTGGCTTCTATTCCTAGTGTC
    AATCACTCTAATACCATTGCCAATTTTATCAAGGGTTACTATGTCAAGCAAAATTATGAA
    AATCAGCAGGTTCACATTGTTACCAGACTAGATAGGGACACTTCTGGCTTGATGCTCTTT
    GCCAAGCACGGTTATGCCCATGCACGATTAGACAAGCAGTTGCAGAAGAAATCTATCGAG
    AAACGCTACTTTGCTTTGGTTAAGGGAGATGGACATTTGGAGCCAGAAGGGGAAATTATT
    GCTCCGATTGCGCGTGATGAAGATTCCATTATTACCAGACGAGTGGCTAAAGGCGGAAAG
    TATGCCCATACTTCATACAAGATTGTAGCTTCTTATGGAAATATTCACTTGGTCTATATT
    CACCTGCACACTGGTCGAACCCATCAAATCCGAGTCCATTTTTCTCATATCGGTTTTCCT
    TTGCTGGGAGATGATTTGTATGGTGGTAGTCTGGAAGATGGTATTCAACGTCAGGCTCTG
    CATTGCCATTACCTATCCTTTTATCATCCATTTTTAGAGCAAGACTTGCAGTTAGAAAGT
    CCCTTGCCGGATGATTTCAGTAACCTTATTACCCAGTTATCAACTAATACTCTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    897

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034183_10080 [new locus tag: SPN034183_RS05440 ]
  • symbol: SPN034183_10080
  • description: putative RNA pseudouridylate synthase
  • length: 298
  • theoretical pI: 6.94468
  • theoretical MW: 33966.4
  • GRAVY: -0.300671

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 240.3)
    and 3 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 90)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 39.4)
    Metabolism Energy metabolism TCA cycle isocitrate dehydrogenase, NADP-dependent (TIGR00127; EC 1.1.1.42; HMM-score: 10)
  • TheSEED  :
    • Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type
    Protein Metabolism Protein biosynthesis Ribosome biogenesis bacterial  Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type
  • PFAM:
    PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 113.7)
    and 1 more
    S4 (CL0492) S4_2; S4 domain (PF13275; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002661
    • TAT(Tat/SPI): 0.000447
    • LIPO(Sec/SPII): 0.000478
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP32718 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQNATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNHSNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIEKRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLVYIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDLQLESPLPDDFSNLITQLSTNTL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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