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serotype 4
D39
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Hungary19A-6
serotype 19A
EF3030
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670-6B
serotype 6B
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serotype 6A
70585
serotype 5
A026
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A66
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AP200
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ATCC 49619
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ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
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HU-OH
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Hu15
serotype 19A
Hu17
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INV104
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INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F01590 [new locus tag: SPN23F_RS00845 ]
  • pan locus tag?: PNEUPAN000872000
  • symbol: SPN23F01590
  • pan gene symbol?: dapE
  • synonym:
  • product: putative peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F01590 [new locus tag: SPN23F_RS00845 ]
  • symbol: SPN23F01590
  • product: putative peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 152000..153373
  • length: 1374
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGTTTTTCCTAGCGAACAAGAACAGATTGAAAAATTTGAAAAGGATCATGTAGCCCAG
    CATTATTTTGAGGTTTTGCGTACCTTGATTTCTAAGAAATCAGTCTTTGCCCAGCAGGTT
    GGACTCAAGGAAGTCGCAAATTATCTGGGTGAGATTTTCAAGCGTGTTGGAGCTGAAGTG
    GAGATTGATGAGAGCTATACAGCGCCCTTTGTCATGGCACATTTCAAGAGTTCGCGTCCA
    GATGCCAAGACCTTGATTTTCTATAACCACTATGACACTGTGCCAGCGGATGGGGATCAG
    GTCTGGACAGAGGATCCTTTTACGCTTTCGGTCCGCAATGGCTTCATGTATGGGCGTGGA
    GTTGATGACGACAAGGGTCATATCACAGCTCGCTTGAGTGCTTTGAGAAAATATATGCAG
    CACCATGATGATTTACCTGTCAATATCAGCTTTATCATGGAGGGAGCGGAGGAATCGGCT
    TCAACAGACCTAGATAAGTATTTGGAAAAGCATGCAGACAAACTCCGTGGGGCGGATTTG
    TTGGTCTGGGAACAAGGGACCAAAAATGCCTTGGAACAGCTGGAAATTTCTGGTGGCAAT
    AAGGGGATTGTGACCTTTGATGCCAAGGTAAAAAGCGCTGATGTGGATATCCACTCGAGT
    TATGGTGGTGTTGTGGAATCAGCTCCTTGGTATCTCCTCCAAGCCTTACAGTCTCTTCGT
    GCTGCGGATGGCCGTATCTTGGTTGAAGGCTTGTACGAAGAAGTACAAGAGCCCAATGAA
    CGAGAAATGGCCTTGCTAGAAACTTATGGTCAACGAAACCCAGAGGAAGTTAGTCGGATT
    TATGGATTGGAGTTGCCTCTCTTACAGGAGGAGCGGATGGCCTTTCTAAAACGTTTCTTT
    TTCGATCCAGCGCTTAATATCGAAGGAATCCAGTCTGGTTATCAAGGTCAGGGTGTTAAG
    ACTATTTTACCTGCAGAAGCCAGTGCCAAGCTAGAGGTTCGTCTGGTTCCGGGCCTAGAA
    CCGCATGATGTTCTGGAAAAAATTCGGAAACAGCTAGACAAAAATGGCTTTGATAAGGTA
    GAATTATACTATACCTTGGGAGAGATGAGCTATCGAAGCGATATGAGCGCACCAGCCATT
    CTCAATGTGATCGAGTTGGCCAAGAAATTCTATCCACAGGGCGTTTCAGTCTTGCCGACG
    ACAGCGGGGACAGGACCTATGCATACGGTCTTTGATGCCCTAGAGGTACCAATGGTTGCA
    TTCGGTCTAGGAAATGCCAATAGCCGAGACCACGGTGGAGATGAAAATGTGCGAATCGCT
    GATTATTACACCCATATCGAATTAGTAGAGGAGCTGATTAGAAGCTATGAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1374

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F01590 [new locus tag: SPN23F_RS00845 ]
  • symbol: SPN23F01590
  • description: putative peptidase
  • length: 457
  • theoretical pI: 4.65645
  • theoretical MW: 51471.7
  • GRAVY: -0.34639

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 105.1)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 89.9)
    and 8 more
    Metabolism Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 76.4)
    putative dipeptidase (TIGR01887; EC 3.4.13.-; HMM-score: 52.8)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides dipeptidase PepV (TIGR01886; EC 3.4.13.-; HMM-score: 47.5)
    N-acetyl-ornithine/N-acetyl-lysine deacetylase (TIGR01902; HMM-score: 44.4)
    Metabolism Amino acid biosynthesis Aspartate family succinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 41.6)
    N-acyl-L-amino-acid amidohydrolase (TIGR01880; EC 3.5.1.14; HMM-score: 37.5)
    putative selenium metabolism hydrolase (TIGR03526; HMM-score: 23.7)
    hydrolase, peptidase M42 family (TIGR03106; HMM-score: 11.7)
  • TheSEED  :
    • Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
  • PFAM:
    Peptidase_MH (CL0035) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 112.8)
    and 3 more
    no clan defined M20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 75.2)
    Peptidase_MH (CL0035) Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 15.5)
    no clan defined BMC; BMC domain (PF00936; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003073
    • TAT(Tat/SPI): 0.001004
    • LIPO(Sec/SPII): 0.000282
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CAR68019 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKEVANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVWTEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESASTDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIHSSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEEVSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVRLVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYPQGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVEELIRSYE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: MtaR* (repression) regulon
    MtaR*(TF)important in Methionine metabolism; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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