Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 06-FEB-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F09810 [new locus tag: SPN23F_RS12235 ]
- pan locus tag?: PNEUPAN002109000
- symbol: SPN23F09810
- pan gene symbol?: —
- synonym:
- product: putative lantibiotic export protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F09810 [new locus tag: SPN23F_RS12235 ]
- symbol: SPN23F09810
- product: putative lantibiotic export protein
- replicon: chromosome
- strand: +
- coordinates: 945774..947897
- length: 2124
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: FM211187 (945774..947897) NCBI
- BioCyc: see SPN23F_RS12235
- MicrobesOnline: 5830844 MicrobesOnline
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101ATGACTAGAAAAGTACCTAATATTGAGCAAATGTCTCAAATAGAATGTGGTTTATGTTGC
TGCTTGTCCATACTACATTTCTATAAAAGCAAAGAGACATTACTAGATTTAAGACGTGAT
ATAGAAAAAGGGAGAGATGGTTATAGTATAGGTGACTTGAAACAGTTATTGAATAAACGA
AATTTTGATACTGGCTCATATCAAGTTAAAGATGTAAATAAAATTAGTGAACTTCCGTTA
CCATTAATAGCATTCTGGGATAATCAACATTATGTAGTTATTTACAAAGTAAAAAAGAAT
AAGGTCTATATAATGGATCCTTCTAAAGGATATATAAATTATGAGTTTAAGGAGTTTTCA
AAACATTTTAGTAATATAGTACTGCTATCATTTCCTAACGAAAATTATCAATCTTTGAAG
TCGCAGTTTCCTTCTCCATGGATAAGAGTATTCTCTAGTTTTTCAAAGGTAAAAGGTCGA
TTGATTTTGACGTTACTATTTTCAATAATAAGTTACTTAATAATACTTTCCGTACCAGTA
ATGACTTCAAAGTTTATTAATTCTGCATTAGGGAATACATTTTCTTTTCAAACCTCGTTT
TTAATTTTATTTTCTCTACTTTGTTTGTATCTTATTTCTATCTTGGCTAGGAGTATGGGA
ATTCTATTTTCTAATATATTTTTTAGTAGAGATATTGAAAGTTTTACATTTAAGCATTTG
CTTAAACTACCATATAGTTTTTTTGAACTCAGGGCAAAAGGAGATATTTTATACAGAATT
TCTAGTCTTAGTGGTTTTAGGGAGCTATTTACTAACCAAGTTGTTGGGGGAGTAGTAGAT
ATCGGGACTATTCTAAGTGTTGTAATATATATGTTTCTTAGTTCAAAAACATTATCAATT
ATAGCTCTTATATTGAGTTTAATCAATTTTTTGTTTCTGTTTAGTACTAGAAAAATAATG
TATGATACGGTTAATAGAGAATTACAAGAACAATCATTGATTTACTCAGTAGAAACAGAA
GCATTAAATACTATTTCTTCAATAAAAATATCGGGATTAGAAGATGAAATATATGAAAAC
TGGTCTAAGTATTTAAAAAACGTATTGACAAAGTATAAAAAACGAAGTATTGTGCATATT
TTATACAATTCAGCTACTAATGTATTTCAATTGTTCGCTCCTATAATTATATTGATTTTT
GGACTTGATAATGTTTTAAATGGAAAAATTTTATTGGGTGAGGTTGTCGCATTTCAAACC
ATGGCATCAATTTTATTTAGTTCAGAAATCTCAATATTTAATGCTTATACGCAGTATATT
TTGGCAGCAGGATACTTAAATAGAGTAAATGATATCTGGCTTGAAAATGAAGAGAATGTT
GAAAATGGTCTTAAAAAGTGTTCTTTAGAAGGTAGAATAGATATTAAGGACCTATCTTTC
TCTTATTCCAAAGACTCAGCTCCTGTAATAGAAAATTTAAATTTGACTATTGAGCCAGGA
CAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACTA
TCAGGATTATATAAGATTGATACAGGAAAAATTTTATTTGATGGTGTAAATATTAATCAA
ATAGATAAAAAAATATTAAGTCAAAATTTAGGAGTAGTTCCACAGGATTCATTTTTATTG
AACCGAAGTATTCTTGATAATATAACTTTAAAGAACGAAGTTACTTCACAAAAGATAGAG
GAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAAT
ACTATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTG
GCACGTGCATTAATAAATAATCCTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTA
GACACTATTAATGAGGAAAGAATAACAAAGTATATACAAAGTCAGGGTTGTACTCAAATA
ATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATGAAAGGT
GGTAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTAC
AGCTTATATACAAAAAGGAAATGA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1200
1260
1320
1380
1440
1500
1560
1620
1680
1740
1800
1860
1920
1980
2040
2100
2124
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F09810 [new locus tag: SPN23F_RS12235 ]
- symbol: SPN23F09810
- description: putative lantibiotic export protein
- length: 707
- theoretical pI: 9.10159
- theoretical MW: 80264
- GRAVY: 0.136068
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 523.3)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 523.3)and 76 moreProtein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 401.6)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 383.7)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 383.7)Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 344.2)Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 344.2)Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 344.2)Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 325.3)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 325.3)Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 317.6)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 290.1)Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 290.1)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 278.3)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 225.6)Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 212.3)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 185.6)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 184)Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 146)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 139.7)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 121.9)Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 121)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 119.1)Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 119)Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 117)Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 108.9)Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 107.5)Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 106.8)Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 106.8)Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 106.7)Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 103.8)Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 102.9)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 102.4)Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 98.9)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 98.4)Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 93.7)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 93.7)D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 93.6)Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 89.7)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 88.6)Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 88)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 87.2)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 85.1)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 84.8)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 84.4)Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 84.4)Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 83.5)Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 83.5)Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 81.6)Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 80.2)Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 79.7)Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 78.4)Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 75.9)Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 75.9)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 73.1)Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 72.5)Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 71.4)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 69.5)Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 68.5)Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 68)Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 68)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 66.2)Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 64.5)Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 61)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 59.9)Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 58.9)Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 58.9)Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 54.8)Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 52.1)Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 47.6)DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 33)Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 17)Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 16.4)DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 16.4)Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 13)Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03496; EC 3.6.3.14; HMM-score: 12)Cellular processes Pathogenesis type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 11.9)Protein fate Protein and peptide secretion and trafficking type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 11.9)
- TheSEED :
- toxin secretion ABC transporter, ATP-binding/permease protein
- PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 124.5)Peptidase_CA (CL0125) Peptidase_C39; Peptidase C39 family (PF03412; HMM-score: 111.9)and 16 moreABC_membrane (CL0241) ABC_membrane; ABC transporter transmembrane region (PF00664; HMM-score: 97.2)P-loop_NTPase (CL0023) SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 32.4)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 19.6)AAA_18; AAA domain (PF13238; HMM-score: 16.4)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 16.4)AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 15.6)MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 14.4)AAA_30; AAA domain (PF13604; HMM-score: 14.2)AAA_25; AAA domain (PF13481; HMM-score: 12.4)AAA_22; AAA domain (PF13401; HMM-score: 12.3)AAA_24; AAA domain (PF13479; HMM-score: 11.8)AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 11.6)Peptidase_CA (CL0125) Guanylate_cyc_2; Guanylylate cyclase (PF09778; HMM-score: 11.5)P-loop_NTPase (CL0023) DUF87; Helicase HerA, central domain (PF01935; HMM-score: 10.5)ABC_ATPase; ATPase of the ABC class (PF09818; HMM-score: 10.1)PduV-EutP; Ethanolamine utilisation - propanediol utilisation (PF10662; HMM-score: 9.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.9902
- Cell wall & surface Score: 0
- Extracellular Score: 0.0097
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006289
- TAT(Tat/SPI): 0.000349
- LIPO(Sec/SPII): 0.0066
- predicted transmembrane helices (TMHMM): 5
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CAR68805 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKGRDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKVYIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGRLILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARSMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVGGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLIYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLFAPIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]