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70585
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A026
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serotype 23F
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SPN994038
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serotype 1

NCBI: 06-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F10980 [new locus tag: SPN23F_RS05570 ]
  • pan locus tag?: PNEUPAN002461000
  • symbol: SPN23F10980
  • pan gene symbol?: PTS-EII_13
  • synonym:
  • product: sugar phosphotransferase system (PTS), IIA component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F10980 [new locus tag: SPN23F_RS05570 ]
  • symbol: SPN23F10980
  • product: sugar phosphotransferase system (PTS), IIA component
  • replicon: chromosome
  • strand: -
  • coordinates: 1073263..1073739
  • length: 477
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGTATTAGATTATTTCTTTGACAAAAACCTTGTGTTTTGCTTAGAAGCGGATAATCAA
    GAACAACTCTTTGATCAGGTAGCAAGCTTGTTGGAAGAACGAGAAATTGTCACTCCAACT
    TATCGTGAAGCCTTGATCACGCGTGAAAAGTCATTTCCAACTGGTTTAGATATGGAATTT
    CTAGGAAAGGACTTGCCAAATGTAGCGATTCCTCACACAGATATTGTTCATAATCTAGCT
    GAAAAAGTGGTGGTTGTTCGATTAGAAAAACCAGTAACTTTTCACAATATGATAGCTCCT
    GATAAGGAAGTAGAAGTATCCCTACTCTTCTTTATCATTAACAATTCAAGTTCAAGTCAA
    ACAAATATTCTGGCTCAGTTGATGGACTTTTTCACAGGAAATGGACATCTTGAAGATTTA
    TCAAAAATTTCCGAACCAGAAAAACTTTATGCTTACATTGCTGAAGCAATCGCTTAA
    60
    120
    180
    240
    300
    360
    420
    477

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F10980 [new locus tag: SPN23F_RS05570 ]
  • symbol: SPN23F10980
  • description: sugar phosphotransferase system (PTS), IIA component
  • length: 158
  • theoretical pI: 4.24157
  • theoretical MW: 17966.4
  • GRAVY: 0.0265823

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 30.9)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 30.9)
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 26.8)
  • TheSEED  :
    • PTS system, galactose-specific IIA component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  PTS system, galactose-specific IIA component (EC 2.7.1.69)
  • PFAM:
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 125.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001817
    • TAT(Tat/SPI): 0.000147
    • LIPO(Sec/SPII): 0.000272
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CAR68909 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, LacR* (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 
    LacR*(TF)important in Lactose utilization, Galactose utilization; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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