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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-FEB-2015

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F12980 [new locus tag: SPN23F_RS06570 ]
  • pan locus tag?: PNEUPAN002549000
  • symbol: orf19
  • pan gene symbol?: orf19
  • synonym:
  • product: conjugative transposon protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F12980 [new locus tag: SPN23F_RS06570 ]
  • symbol: orf19
  • product: conjugative transposon protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1270376..1270597
  • length: 222
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAATTTTGGACAAAACCTTTATAACTGGTTTCTATCAAACGCTCAATCACTGGTGCTT
    TTAGCAATCGTTGTGATTGGCTTGTATCTTGGCTTCAAGCGTGAGTTTAGCAAACTGATT
    GGCTTTTTAATTATTGCGATTATTGCGGTTGGCTTAGTCTTCAACGCTGCTGGAGTAAAA
    GACATTTTACTAGAGCTATTCAATCGCATTATTGGTGCTTAA
    60
    120
    180
    222

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPN23F12980 [new locus tag: SPN23F_RS06570 ]
  • symbol: Orf19
  • description: conjugative transposon protein
  • length: 73
  • theoretical pI: 9.86435
  • theoretical MW: 8058.65
  • GRAVY: 1.17534

Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions Protein interactions Phr family secreted Rap phosphatase inhibitor (TIGR04429; HMM-score: 9.7)
    and 1 more
    PEF-CTERM protein sorting domain (TIGR03024; HMM-score: 5)
  • TheSEED  :
    • FIG086557: Conjugation related protein
  • PFAM:
    TrbC_VirB2 (CL0690) TrbC; TrbC/VIRB2 pilin (PF04956; HMM-score: 15.4)
    and 5 more
    O-anti_assembly (CL0499) Wzy_C; O-Antigen ligase (PF04932; HMM-score: 10.3)
    no clan defined DUF6097; Family of unknown function (DUF6097) (PF19592; HMM-score: 9.7)
    DUF6341; Family of unknown function (DUF6341) (PF19868; HMM-score: 7.1)
    Flp1_like; Putative Flagellin, Flp1-like, domain (PF16982; HMM-score: 6.7)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.797
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.2029
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002349
    • TAT(Tat/SPI): 0.000145
    • LIPO(Sec/SPII): 0.001218
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CAR69100 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLVFNAAGVKDILLELFNRIIGA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]