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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 11-FEB-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
 - locus tag: SPN23F_RS05520 [old locus tags: SPN23F10870 SPN23F_10870 ]
 - pan locus tag?: PNEUPAN002428000
 - symbol: SPN23F_RS05520
 - pan gene symbol?: lacF-2
 - synonym:
 - product: PTS lactose/cellobiose transporter subunit IIA
 
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
 - locus tag: SPN23F_RS05520 [old locus tags: SPN23F10870 SPN23F_10870 ]
 - symbol: SPN23F_RS05520
 - product: PTS lactose/cellobiose transporter subunit IIA
 - replicon: chromosome
 - strand: -
 - coordinates: 1067125..1067442
 - length: 318
 - essential: unknown
 
⊟Accession numbers[edit | edit source]
- Location: NC_011900 (1067125..1067442) NCBI
 - BioCyc: SPN23F_RS05520 BioCyc
 - MicrobesOnline: see SPN23F10870
 - PneumoBrowse for strain D39V: SPV_1048 PneumoBrowse
 
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301ATGAATAGAGAAGAAGTAACATTGTTAGGTTTTGAAATCGTAGCCTATGCTGGCGATGCT
CGTTCAAAACTATTGGAAGCCTTGAAGGCTGCTGAAGCTGGTGATTTTGAAAAAGCGGAC
GCTCTGGTAGAGGAAGCTGGTAGCTGTATTGCAGAGGCTCACCACGCGCAAACAAGTCTA
TTGACTAAGGAAGCTTCTGGTGAGGACTTAGCGTATAGTGTGACCATGATGCATGGTCAA
GATCACTTGATGACAACTATCTTGTTAAAAGACCTAATGCACCATTTAATTGAACTTTAC
AAGAGAGGAGTTAAATAA60
120
180
240
300
318 
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F_RS05520 [old locus tags: SPN23F10870 SPN23F_10870 ]
 - symbol: SPN23F_RS05520
 - description: PTS lactose/cellobiose transporter subunit IIA
 - length: 105
 - theoretical pI: 4.91829
 - theoretical MW: 11513.1
 - GRAVY: -0.0742857
 
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, lactose-specific IIa component (TIGR00823; EC 2.7.1.69; HMM-score: 159.4)and 1 moreUnknown function Enzymes of unknown specificity uncharacterized pyridoxal phosphate-dependent enzyme (TIGR01437; HMM-score: 14.5)
 - TheSEED: see SPN23F10870
 - PFAM: no clan defined PTS_IIA; PTS system, Lactose/Cellobiose specific IIA subunit (PF02255; HMM-score: 116)
 
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
 - modifications:
 - cofactors:
 - effectors:
 
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
 - Cytoplasmic Membrane Score: 0
 - Cellwall Score: 0.01
 - Extracellular Score: 0.02
 - Internal Helices: 0
 
 - DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9975
 - Cytoplasmic Membrane Score: 0.0006
 - Cell wall & surface Score: 0.0001
 - Extracellular Score: 0.0017
 
 - SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.018708
 - TAT(Tat/SPI): 0.006037
 - LIPO(Sec/SPII): 0.00369
 
 - predicted transmembrane helices (TMHMM): 0
 
⊟Accession numbers[edit | edit source]
- GI:
 - RefSeq: WP_001078331 NCBI
 - UniProt:
 
⊟Protein sequence[edit | edit source]
- MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVEEAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKRGVK
 
⊟Experimental data[edit | edit source]
- protein localization:
 - interaction partners:
 
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: CcpA see SPN23F10870
 
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1048 PneumoExpress
 
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]