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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
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A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 49619
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ATCC 700669
serotype 23F
BM6001
serotype 19F
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CGSP14
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G54
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HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS05775 [old locus tags: SPN23F11390 SPN23F_11390 ]
  • pan locus tag?: PNEUPAN002493000
  • symbol: ftsY
  • pan gene symbol?: ftsY
  • synonym:
  • product: signal recognition particle-docking protein FtsY

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS05775 [old locus tags: SPN23F11390 SPN23F_11390 ]
  • symbol: ftsY
  • product: signal recognition particle-docking protein FtsY
  • replicon: chromosome
  • strand: -
  • coordinates: 1113056..1114345
  • length: 1290
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTA
    AAAGAAGCTCTGGAAAATCTTGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTT
    GAGGAAGTTCCTCAGGAAGAAGCAGAGGTTGAAATTGTTGAACAAGCTGTGTTCCAAGAG
    GAGGAAATCCAAGACACAGTTGAAGAAAGTCAGGATTCAGAGCCAGCTGTAGGGGTTTCT
    CAAGAAGAAATAGAAGAATTACCAAACTCAGAAGAATTACCAGAGGAAGAGAAGCTTGAG
    CACGAAGGAACTGTAGAAGAAAATAATTCTGAAGTTCTTGAACCAGAAAGGCCTCAAACA
    GAAGAAACTGTTCAGGAAAAATATGACCGCAGTCTCAAGAAGACTCGTACGGGCTTCGGT
    GCTCGCTTGAACGCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAA
    CTGGAAGAACTGCTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAG
    GAACTACGTTACGAAGCCAAGCTTGAAAATGCCAAGAAACCTGATGCACTTCGTCGTGTC
    ATCATTGAGAAATTGGTTGAGCTTTATGAAAAGGATGGTAGCTACGATGAAAGCATCCAC
    TTCCAAGATAACTTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACT
    TCTATTGGAAAACTAGCCCACCGCTACAAACGAACTGGTAAGAAGGTCATGCTGGTTGCA
    GCAGATACCTTCCGTGCGGGTGCAGTAGCTCAGCTAGCTGAATGGGGCCGACGAGTAGAT
    GTTCCAGTAGTAACTGGACCTGAAAAAGCTGATCCAGCCAGCGTGATCTTTGACGGTATG
    GAACGTGCCGTGGCTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAA
    AATAAGGATAACCTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTG
    CCAGAAGCACCACATGAAACCTTCTTGGCACTTGATGCATCAACAGGTCAAAATGCCCTA
    GTACAGGCCAAAGAATTTTCGAAAATCACACCTTTAACGGGAATTGTTTTGACTAAGATT
    GATGGAACTGCTCGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTA
    AAATTGATTGGTTTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTT
    ATGAAAGGTCTCTTGGAAGGCTTAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1290

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS05775 [old locus tags: SPN23F11390 SPN23F_11390 ]
  • symbol: FtsY
  • description: signal recognition particle-docking protein FtsY
  • length: 429
  • theoretical pI: 4.15672
  • theoretical MW: 47911.6
  • GRAVY: -0.372494

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle-docking protein FtsY (TIGR00064; HMM-score: 354)
    and 11 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle protein (TIGR00959; HMM-score: 210.7)
    signal recognition particle protein SRP54 (TIGR01425; HMM-score: 172.6)
    Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 87.9)
    Genetic information processing Protein fate Protein modification and repair hydrogenase accessory protein HypB (TIGR00073; HMM-score: 23.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 18.5)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 18.5)
    Hypothetical proteins Conserved transport-energizing ATPase, TRC40/GET3/ArsA family (TIGR00345; EC 3.6.1.-; HMM-score: 13.8)
    arsenical pump-driving ATPase (TIGR04291; EC 3.6.1.-; HMM-score: 13.6)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 13.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions dTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 12.4)
    cell division ATPase MinD (TIGR01969; HMM-score: 11.3)
  • TheSEED: see SPN23F11390
  • PFAM:
    P-loop_NTPase (CL0023) SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 251.7)
    and 24 more
    no clan defined SRP54_N; SRP54-type protein, helical bundle domain (PF02881; HMM-score: 48.9)
    P-loop_NTPase (CL0023) CbiA; CobQ/CobB/MinD/ParA nucleotide binding domain (PF01656; HMM-score: 22.7)
    AAA_30; AAA domain (PF13604; HMM-score: 22.6)
    MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 17.8)
    AAA_22; AAA domain (PF13401; HMM-score: 17.7)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 17.3)
    AAA_31; AAA domain (PF13614; HMM-score: 17)
    AAA_25; AAA domain (PF13481; HMM-score: 16.3)
    AAA_33; AAA domain (PF13671; HMM-score: 15.4)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 14.3)
    ArsA_ATPase; Anion-transporting ATPase (PF02374; HMM-score: 14.1)
    AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 13.9)
    Fer4_NifH; 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family (PF00142; HMM-score: 13.4)
    AAA_19; AAA domain (PF13245; HMM-score: 13.4)
    AAA_15; AAA ATPase domain (PF13175; HMM-score: 13.2)
    Thymidylate_kin; Thymidylate kinase (PF02223; HMM-score: 13)
    ABC_tran; ABC transporter (PF00005; HMM-score: 12.9)
    no clan defined DUF3801; Protein of unknown function (DUF3801) (PF12687; HMM-score: 12.2)
    P-loop_NTPase (CL0023) YqeC; YqeC protein (PF19842; HMM-score: 12)
    AAA_23; AAA domain (PF13476; HMM-score: 11.9)
    MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 11.6)
    no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 10.7)
    P-loop_NTPase (CL0023) ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 9.9)
    VBS-like (CL0705) Vinculin; Vinculin family (PF01044; HMM-score: 6.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.4981
    • Cytoplasmic Membrane Score: 0.4584
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0425
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003271
    • TAT(Tat/SPI): 0.000143
    • LIPO(Sec/SPII): 0.000257
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000522315 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVPQEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHEGTVEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVIFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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