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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 11-FEB-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F_RS06425 [old locus tags: SPN23F12690 SPN23F_12690 ]
- pan locus tag?: PNEUPAN000570000
- symbol: SPN23F_RS06425
- pan gene symbol?: —
- synonym:
- product: peptidase domain-containing ABC transporter
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F_RS06425 [old locus tags: SPN23F12690 SPN23F_12690 ]
- symbol: SPN23F_RS06425
- product: peptidase domain-containing ABC transporter
- replicon: chromosome
- strand: -
- coordinates: 1234839..1236962
- length: 2124
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_011900 (1234839..1236962) NCBI
- BioCyc: SPN23F_RS06425 BioCyc
- MicrobesOnline: see SPN23F12690
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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2101TTGAAAAAGGTAAAATTCATACAACAATTATCTGAGACCAGTTGTGGTTTAGCATGCATG
GCAATGATTTTAGATTATTATGGGCATGAGGCAAACTTATATGAATTATGCTGTGATTTT
GAGAATTCAAGGGATGGATTATCCATTAGAGAGATTAAAGATATAGCTTCTTATTTTGGA
TTGGATTCAAAGGCGACTGAGATCTTAAATATTAAAAAATTTTTGGGGAACAAATTTGTA
GAACCTTATATAGCTTTAACTCAAAATGCTCATTATATTGTGGTGGAAAAACATAATGAG
CATAGTGTAGTATTCATTGATCCAGAACGAGGTAGAATTACAGAAGATATATCAAACTTT
GCGAATAATATATCTGGTATTGTAATTTTCTTCTCACCAAATAGGAAATTCACTAAAAAA
AAGAAGCATAGTAATTTTTTTAAAATATTGAAGATAGGTAAAATTGATATTAAAAGGCTA
TGTTATATTTCTTTAATATCAATTTTGGTACAGAGTCTCACCTTATTATTACCTTTGCTA
ACAAGGTTTATTATTGATAATGTAATTAGCAAAGGAGAAATGTATCGTTTAGGGATGCTT
TTTTCAATCTTTTCTTTAATAACATTTTATGCATTATTTAGCTTTATACGAACTAAATTA
ATTATTACAGTTGAAAAGAGATACATATTTACATTAAAAGATAAAATTGTTGGCAAAATT
TTCACTCTACCTATGAAATTTTTTGATAGTAGATCTTCAGGTGAAATTGTAACTCGAATC
AATAATTTAGATTCTTTAGAGAAAATAATTTCAAGTGGAATATCAAGTTTGTTAATTGAT
CTATCTACAATTATTATCGCTTTTATAGCTATGGCAATGATTTCATTATATTTCACACTT
ATAATCACATGTTTTGCTATATTTTTGTTTATTGTTTTATATTTTTTGTTAAAAAAATTG
GAAGAAAAGAACTCAAACTTTATCAGTTCTAAAGAATTGACTCAAGGTTATTTGATGGAA
ATTTTTTCTAATTTATTATTTTTGAAAGTCTCAGCAAAAGGAGATGTTTCATATACTAAG
TGGAAAGAAATGTTTAGTAATGAGCTTAAATTTGATGTAGAGCGTGAAAATTATCTAAAT
ATTTTTCAGACTTTTATTTCTATTTATAGACTCGTACCAAACTTACTAATTTTAATTTTG
GGAGGACTAGAAGTACAGCAGCATATGATGTCTCTGGGGAGTTTAATGTCATTTTTATCA
TTGGTATCTTTGCTTCTTTCACCTATTACTCTAATCGTACAAAACTGTTTTCAATTTCAA
TTTTGTTTTACAATTTTAGATAGAGTGTTTGATATCATTTATACTCCAGAAGAAAAAAAT
CAATTTTCTATTTCTAAACTACCCCCATTTGAAATGATGACTTTCAGAAATTTGAGTTTT
GCTTATAGTAGTGCCTGTAAAGTTATTTATGATATATCATTAACTATTAAGAAAGGTGAA
CGTATTGCTATAGTGGGGAGGACAGGTTGCGGAAAAACTACACTTATTAAATTATTGCTA
CGGCTGTATGATGTAGAGAAAAATACGATTTTATATAATGGTAATGATATTAATTTATTT
GATTTAAATAGTTATAGGAAGAGTTTCGGAGTTGTTTTACAAAATGATGTAATGTTTAAC
GACACTGTGATTTCCAATATAGATTTAACTCATAGCCATTCTATGGAGGATGTCATTTCT
GCAGCAAGTTTAGCTGAATTAGATATAGAGATTAATAATATGCCTATGGGATACTATACT
AGTATTGGGGATAATGGTAACAATTTATCAGGTGGGCAAAGGCAACGCTTAGCAATAGCT
CGAGCCATTTTGCAAAATCCAGAGATTATAATTTTTGATGAAGGTACTGGTCAATTGGAC
ACTATAACAGAGAAGAAAATAATGGATAATTTAAAACATAAAGGAATTACCCAAATTTTT
ATAACTCATAGACTATCTAACGCTCAGGAATACGATAATATTATTGTTATGGATAACGGT
AAAATCATAGATAGCGGAAAACATGATGAGTTATGTGGTAAAGAAGGTATGTATAAAAGG
CTTTTTGAAACCTCATATAATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F_RS06425 [old locus tags: SPN23F12690 SPN23F_12690 ]
- symbol: SPN23F_RS06425
- description: peptidase domain-containing ABC transporter
- length: 707
- theoretical pI: 8.173
- theoretical MW: 80945.3
- GRAVY: 0.19024
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 436.5)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 436.5)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 375)Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 368.7)Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 368.7)Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 368.7)Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 360.8)Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 360.8)and 74 moreCellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 323.4)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 323.4)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 302.4)Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 302.4)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 281)Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 234.4)Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 220.7)Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 218.7)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 191.2)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 164.7)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 130.7)Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 126)Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 125.4)Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 124.2)Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 121)Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 113.3)Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 111.4)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 107.7)Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 107.6)Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 107.6)Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 106)Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 103)Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 98.4)Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 96.1)Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 95)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 93.7)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 92)Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 88.4)Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 86.5)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 86.4)Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 85.4)Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 84.7)Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 84.7)Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 84.3)Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 84.3)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 84)Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 82.3)Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 81.1)Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 81.1)D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 77.6)Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 76.6)Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 75.4)Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 74.6)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 72.8)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 67)Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 66.6)Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 63.6)Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 62.7)Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 59.9)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 58.9)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 57.5)Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 56.3)Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 56.3)Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 54.1)Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 54.1)Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 54.1)Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 53.7)Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 52.1)Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 52.1)Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 50.8)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 50.6)Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 39.4)DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 22.1)Cellular processes Pathogenesis type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 18.8)Protein fate Protein and peptide secretion and trafficking type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 18.8)Energy metabolism Amino acids and amines ethanolamine utilization protein, EutP (TIGR02528; HMM-score: 16.7)Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 15.3)P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 14.2)Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 13.4)Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03497; EC 3.6.3.14; HMM-score: 12.8)Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03496; EC 3.6.3.14; HMM-score: 12)Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 12)flagellar protein export ATPase FliI (TIGR03498; EC 3.6.3.14; HMM-score: 10.9)helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 10.5)
- TheSEED: see SPN23F12690
- PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 113.8)Peptidase_CA (CL0125) Peptidase_C39; Peptidase C39 family (PF03412; HMM-score: 100.4)ABC_membrane (CL0241) ABC_membrane; ABC transporter transmembrane region (PF00664; HMM-score: 91.7)and 26 moreP-loop_NTPase (CL0023) AAA_22; AAA domain (PF13401; HMM-score: 21.7)Peptidase_CA (CL0125) Peptidase_C39_2; Peptidase_C39 like family (PF13529; HMM-score: 21.7)Peptidase_C70; Papain-like cysteine protease AvrRpt2 (PF12385; HMM-score: 19.5)P-loop_NTPase (CL0023) ATP-synt_ab; ATP synthase alpha/beta family, nucleotide-binding domain (PF00006; HMM-score: 19.1)SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 18.4)AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 16.9)MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 16.5)Peptidase_CA (CL0125) Guanylate_cyc_2; Guanylylate cyclase (PF09778; HMM-score: 16.5)P-loop_NTPase (CL0023) DUF87; Helicase HerA, central domain (PF01935; HMM-score: 15.6)AAA_14; AAA domain (PF13173; HMM-score: 15)ABC_ATPase; ATPase of the ABC class (PF09818; HMM-score: 14.6)AAA_18; AAA domain (PF13238; HMM-score: 14.5)TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 13.9)Rad17; Rad17 P-loop domain (PF03215; HMM-score: 13.7)PduV-EutP; Ethanolamine utilisation - propanediol utilisation (PF10662; HMM-score: 13.6)AAA_24; AAA domain (PF13479; HMM-score: 13.6)no clan defined SecA_PP_bind; SecA preprotein cross-linking domain (PF01043; HMM-score: 12.9)P-loop_NTPase (CL0023) AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 12.8)AAA_16; AAA ATPase domain (PF13191; HMM-score: 12.8)AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 12.7)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 12.6)MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 12.2)Viral_helicase1; Viral (Superfamily 1) RNA helicase (PF01443; HMM-score: 12.1)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 12)Zeta_toxin; Zeta toxin (PF06414; HMM-score: 11.6)no clan defined Baculo_11_kDa; Baculovirus 11 kDa family (PF06143; HMM-score: 7.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 6
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0001
- Cytoplasmic Membrane Score: 0.9901
- Cell wall & surface Score: 0
- Extracellular Score: 0.0099
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.132105
- TAT(Tat/SPI): 0.001367
- LIPO(Sec/SPII): 0.033148
- predicted transmembrane helices (TMHMM): 6
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000756060 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKKVKFIQQLSETSCGLACMAMILDYYGHEANLYELCCDFENSRDGLSIREIKDIASYFGLDSKATEILNIKKFLGNKFVEPYIALTQNAHYIVVEKHNEHSVVFIDPERGRITEDISNFANNISGIVIFFSPNRKFTKKKKHSNFFKILKIGKIDIKRLCYISLISILVQSLTLLLPLLTRFIIDNVISKGEMYRLGMLFSIFSLITFYALFSFIRTKLIITVEKRYIFTLKDKIVGKIFTLPMKFFDSRSSGEIVTRINNLDSLEKIISSGISSLLIDLSTIIIAFIAMAMISLYFTLIITCFAIFLFIVLYFLLKKLEEKNSNFISSKELTQGYLMEIFSNLLFLKVSAKGDVSYTKWKEMFSNELKFDVERENYLNIFQTFISIYRLVPNLLILILGGLEVQQHMMSLGSLMSFLSLVSLLLSPITLIVQNCFQFQFCFTILDRVFDIIYTPEEKNQFSISKLPPFEMMTFRNLSFAYSSACKVIYDISLTIKKGERIAIVGRTGCGKTTLIKLLLRLYDVEKNTILYNGNDINLFDLNSYRKSFGVVLQNDVMFNDTVISNIDLTHSHSMEDVISAASLAELDIEINNMPMGYYTSIGDNGNNLSGGQRQRLAIARAILQNPEIIIFDEGTGQLDTITEKKIMDNLKHKGITQIFITHRLSNAQEYDNIIVMDNGKIIDSGKHDELCGKEGMYKRLFETSYN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]