PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 11-FEB-2025

⊟Summary

• organism: Streptococcus pneumoniae ATCC 700669
• locus tag: SPN23F_RS08940 [old locus tags: SPN23F17740 SPN23F_17740 ]
• pan locus tag^?: PNEUPAN003204000
• symbol: SPN23F_RS08940
• pan gene symbol^?: gspA_7
• synonym:
• product: glycosyltransferase family 8 protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPN23F_RS08940 [old locus tags: SPN23F17740 SPN23F_17740 ]
• symbol: SPN23F_RS08940
• product: glycosyltransferase family 8 protein
• replicon: chromosome
• strand: -
• coordinates: 1710035..1711231
• length: 1197
• essential: unknown

⊟Accession numbers

• Location: NC_011900 (1710035..1711231) NCBI
• BioCyc: SPN23F_RS08940 BioCyc
• MicrobesOnline: see SPN23F17740
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  
  ATGAGAAAATCAATAGTATTAGCGGCAGATAATGTCTATCTTATTCCTTTAGAGACGACT
  ATAAAGTCTGTATTGTATCACAATAGAGATGTTGATTTTTATATTCTCAACAGTGATATA
  GCTCCTGAATGGTTTAAATTATTGGGGAGAAAAATGGAAGTTGTGAATTCTACAATTCGC
  AGTGTACACATTGATAAAGAACTTTTTGAAAGCTATAAAACAGGACCTCATATAAATTAT
  GCTTCTTACTTTAGATTTTTTGCGACAGAAGTGGTTGAATCTGATAGGGTATTGTATCTG
  GATTCCGATATCATTGTAACTGGGGAACTAGCTACTTTGTTTGAGATAGATCTCAAAGGA
  TATTCAATTGGTGCTGTTGATGATGTCTATGCCTATGAAGGACGAAAATCTGGATTTAAT
  TCTGGAGTTTTATTAATGGATGTTGCAAAATGGAAAGAACACTCTATTGTCAATAGTTTA
  TTGGAATTAGCGGCCGAGCAAAATCAAGTTGTTCATCTTGGGGATCAGAGTATTTTAAAT
  ATTTATTTTGAGGATAATTGGCTAGCCTTAGATAAAACATATAATTATATGGTAGGTGTT
  GATATTTATCACCTTGCTCAAGAATGTGAACGTCTAGATGACAATCCACCTACAATTGTT
  CACTATGCTAGTCATGATAAACCTTGGAATACATATAGTATATCTAGACTACGTGAATTA
  TGGTGGGTTTATAGAGATTTGGATTGGTCAGAGATTGCTTTTCAACGTTCCGATTTAAAT
  TATTTTGAAAGAAGCAATCAGTCTAAAAAACAAGTGATGCTTGTGACATGGAGTGCAGAT
  ATAAAACATTTAGAGTATTTAGTACAACGGTTACCTGATTGGCATTTTCATTTGGCTGCA
  CCGTGTGATTGTTCTGAGGAGCTGACCTCTCTATCACAGTATACGAATGTAACAGTATAT
  CAAAATGTATTACATAGTAGAATTGATTGGCTATTGGACGATTCTATAGTTTATTTAGAT
  ATTAATACAGGTGGAGAGGTTTTTAATGTAGTTACAAGGGCACAAGAAAGTGGCAAGAAA
  ATCTTCGCTTTTGATATCACACGTAAAAGTATGGATGATGGACTCTATGACGGTATTTTT
  TCTGTGGAGAGACCAGATGATTTAGTGGATAGAATGAAGAATATAGAGATAGAGTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1197
  

⊟Protein

⊟General

• locus tag: SPN23F_RS08940 [old locus tags: SPN23F17740 SPN23F_17740 ]
• symbol: SPN23F_RS08940
• description: glycosyltransferase family 8 protein
• length: 398
• theoretical pI: 4.57542
• theoretical MW: 46332.9
• GRAVY: -0.243216

⊟Function

• reaction:
  EC 2.4.-.-?  ExPASy
• TIGRFAM:
  Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosyltransferase GtfB (TIGR02919; EC 2.4.1.-; HMM-score: 101.2)
• TheSEED: see SPN23F17740
• PFAM:
  GT-A (CL0110) Glyco_transf_8; Glycosyl transferase family 8 (PF01501; HMM-score: 149.8)
  and 2 more
  Glyco_transf_24; Glucosyltransferase 24 (PF18404; HMM-score: 16.7)
  Mannosyl_trans3; Mannosyltransferase putative (PF11051; HMM-score: 13.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9387
  • Cytoplasmic Membrane Score: 0.0267
  • Cell wall & surface Score: 0.0007
  • Extracellular Score: 0.0338
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002541
  • TAT(Tat/SPI): 0.000074
  • LIPO(Sec/SPII): 0.000394
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_001232158 NCBI
• UniProt:

⊟Protein sequence

• MRKSIVLAADNVYLIPLETTIKSVLYHNRDVDFYILNSDIAPEWFKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDSDIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSLLELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPTIVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVTWSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDDSIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRMKNIEIE

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SPN23F_RS13970 < asp5 < asp4 < gtfB < gtfA < secA2 < asp3 < asp2 < asp1 < secY2 < SPN23F_RS08935 < SPN23F_RS08940 < SPN23F_RS08945 < SPN23F_RS08950 < SPN23F_RS08955 < SPN23F_RS08960 < SPN23F_RS08965

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications