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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS10410 [old locus tags: SPN23F20290 SPN23F_20290 ]
  • pan locus tag?: PNEUPAN003653000
  • symbol: nusG
  • pan gene symbol?: nusG
  • synonym:
  • product: transcription termination/antitermination protein NusG

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS10410 [old locus tags: SPN23F20290 SPN23F_20290 ]
  • symbol: nusG
  • product: transcription termination/antitermination protein NusG
  • replicon: chromosome
  • strand: -
  • coordinates: 1972342..1972878
  • length: 537
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGATAGTTTTGATAAAGGATGGTTTGTTTTACAAACTTATTCTGGTTATGAAAATAAG
    GTGAAAGAAAATCTATTACAACGTGCACAAACCTACAATATGTTGGATAATATTCTACGC
    GTTGAAATTCCAACACAAACAGTGCAAGTTGAAAAAAATGGAAAGAGAAAAGAAGTAGAA
    GAAAATCGCTTTCCAGGTTATGTTCTTGTAGAAATGGTCATGACAGATGAAGCTTGGTTT
    GTTGTTCGAAACACACCAAATGTTACAGGATTTGTCGGATCACACGGGAACAGATCAAAA
    CCAACTCCATTATTGGAACAAGAAATTCGTGACATTTTGGTATCTATGGGACAAACTGTT
    CAAGAATTTGATTTCGATGTTGAGATTGGTCAAACTGTACGTATTATTGATGGTGCTTTT
    GCAGACTACACTGGTAAGATTACAGAAATTGATAATAACAAAGTGAAAATGATTATCTCT
    ATGTTTGGTAATGACACAGTTGCAGAAGTAAACCTAAACCAAATCGCAGAATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    537

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS10410 [old locus tags: SPN23F20290 SPN23F_20290 ]
  • symbol: NusG
  • description: transcription termination/antitermination protein NusG
  • length: 178
  • theoretical pI: 4.40864
  • theoretical MW: 20346.9
  • GRAVY: -0.351685

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Transcription Transcription factors transcription termination/antitermination factor NusG (TIGR00922; HMM-score: 167)
    and 4 more
    NusG family protein (TIGR01956; HMM-score: 103.3)
    Genetic information processing Transcription Transcription factors transcription elongation factor/antiterminator RfaH (TIGR01955; HMM-score: 55.8)
    transcription elongation factor Spt5 (TIGR00405; HMM-score: 18.1)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein uL24 (TIGR01080; HMM-score: 14.3)
  • TheSEED: see SPN23F20290
  • PFAM:
    NusG-like (CL0439) NusG; Transcription termination factor nusG (PF02357; HMM-score: 100)
    and 3 more
    KOW (CL0107) KOW; KOW motif (PF00467; HMM-score: 29)
    no clan defined Pik1; Yeast phosphatidylinositol-4-OH kinase Pik1 (PF11522; HMM-score: 12.5)
    PUA (CL0178) PUA_4; RNA methyltransferase PUA domain (PF20260; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006354
    • TAT(Tat/SPI): 0.000343
    • LIPO(Sec/SPII): 0.001266
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000376736 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIISMFGNDTVAEVNLNQIAEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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