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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS13700
  • pan locus tag?: PNEUPAN000789000
  • symbol: SPN23F_RS13700
  • pan gene symbol?:
  • synonym:
  • product: ATPase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS13700
  • symbol: SPN23F_RS13700
  • product: ATPase
  • replicon: chromosome
  • strand: +
  • coordinates: 123682..124221
  • length: 540
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_011900 (123682..124221) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATAAGAAAAAAATGATTTTAACAAGTCTAGCCAGCGTCGCTATCTTAGGGGCTGGT
    TTTGTTGCGTCTTCGCCTACTGTTGTAAGAGCAGAAGACGCTCCACAAGTTGTCGAAAAA
    TCTTCATTAGAGAAGAAATATGAGGAAGCAAAAACAAAAGCTGATACTGCCAAGAAAGAT
    TACGAAACGGCTAAAAAGAAAGCAGAAGACGCTCAGAAGAAATATGATGAGGATCAGAAG
    AAAACTGAAGAGAAAGCGAAAAAAGAGAAAGAAGCTGCTAAGAAAGTAGACGATGCTAGT
    TTAGCGGTACAAAAAGCATATGTAGAATATAGAAAAGTTCAAGAATCTCGTAGTAATTAC
    AGAAATCGGAGTGATTATAATAAAAAATTAGCAGAGGCGCAAGTAAAAATAGATGAAGCG
    AATAAAAAACTAACCGCAGCTAATAATGAGTTTAAAACTGTAAGAGCAGTTGTAGTTCCT
    GAACCAAATGCGTTGGCTGAGACTAAGAAAAAAGCAGAAGAAGCTAAAGCAGAAAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPN23F_RS13700
  • symbol: SPN23F_RS13700
  • description: ATPase
  • length: 179
  • theoretical pI: 10.0687
  • theoretical MW: 20017.6
  • GRAVY: -1.06425

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 16)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 16)
    and 12 more
    SH3 domain protein (TIGR04211; HMM-score: 12)
    SEC10/PgrA surface exclusion domain (TIGR04320; HMM-score: 10.3)
    Genetic information processing Transcription Degradation of RNA ribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 8.7)
    Genetic information processing DNA metabolism Other MutS2 family protein (TIGR01069; HMM-score: 7.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 7.3)
    oligosaccharyl transferase, archaeosortase A system-associated (TIGR04154; EC 2.4.1.-; HMM-score: 7)
    Genetic information processing DNA metabolism Restriction/modification DNA sulfur modification protein DndD (TIGR03185; HMM-score: 6.9)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 6.5)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 6.5)
    Cellular processes Cellular processes Pathogenesis type VI secretion protein IcmF (TIGR03348; HMM-score: 6.2)
    Metabolism Transport and binding proteins Cations and iron carrying compounds ferrous iron transport protein B (TIGR00437; HMM-score: 3.4)
    Hypothetical proteins Conserved TIGR02680 family protein (TIGR02680; HMM-score: 3.3)
  • TheSEED:
  • PFAM:
    no clan defined DUF3450; Protein of unknown function (DUF3450) (PF11932; HMM-score: 13.4)
    LMBR1; LMBR1-like membrane protein (PF04791; HMM-score: 11.1)
    SpoIIIAH; SpoIIIAH-like protein (PF12685; HMM-score: 11.1)
    and 7 more
    GT-B (CL0113) FUT8_N_cat; Alpha-(1,6)-fucosyltransferase N- and catalytic domains (PF19745; HMM-score: 8)
    no clan defined Phlebovirus_NSM; Phlebovirus nonstructural protein NS-M (PF07246; HMM-score: 7.4)
    His_Kinase_A (CL0025) HisKA_3; Histidine kinase (PF07730; HMM-score: 7.3)
    BCLiA (CL0551) ATG14; Vacuolar sorting 38 and autophagy-related subunit 14 (PF10186; HMM-score: 7)
    Golgi-transport (CL0145) IMD; IRSp53/MIM homology domain (PF08397; HMM-score: 6.7)
    no clan defined Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region (PF02932; HMM-score: 6.3)
    V_ATPase_I; V-type ATPase 116kDa subunit family (PF01496; HMM-score: 5.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0009
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0.7548
    • Extracellular Score: 0.2437
  • SignalP: Signal peptide SP(Sec/SPI) length 31 aa
    • SP(Sec/SPI): 0.994729
    • TAT(Tat/SPI): 0.002512
    • LIPO(Sec/SPII): 0.002305
    • Cleavage Site: CS pos: 31-32. VRA-ED. Pr: 0.9712
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_231844674 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNKKKMILTSLASVAILGAGFVASSPTVVRAEDAPQVVEKSSLEKKYEEAKTKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKEKEAAKKVDDASLAVQKAYVEYRKVQESRSNYRNRSDYNKKLAEAQVKIDEANKKLTAANNEFKTVRAVVVPEPNALAETKKKAEEAKAEK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]