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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994038
  • locus tag: SPN994038_16280 [new locus tag: SPN994038_RS08795 ]
  • pan locus tag?: PNEUPAN003385000
  • symbol: SPN994038_16280
  • pan gene symbol?: slyA_1
  • synonym:
  • product: putative MarR-family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN994038_16280 [new locus tag: SPN994038_RS08795 ]
  • symbol: SPN994038_16280
  • product: putative MarR-family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 1648827..1649270
  • length: 444
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312041 (1648827..1649270) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1645 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAAGATAGTCATTTGCTAGCCCATCATATTCGTTTGTTGAATGGGCGGATTTTTCAA
    AAGTTACTGAGTCAAGATCCTGAGGCTCTTTATAGGGGTGAACAGGGCAAGATTTTAGCG
    GTTTTATGGAATAGTGAAACTGGCTGCGCAACTGCGACAGATATCGCGCTTGCGACTGGG
    CTTGCGAATAATACGCTGACGACTATGATAAAAAAGCTAGAGGAACAAAAGCTTGTAATT
    GTTAGTCCGTGTGGAAAAGACAAGCGTAAGAAGTATTTAGTTTTAACGGAGTTAGGCAAG
    TCCCAGAAAGAAGTGGGGCATCGTGTCAGTCAGAAATTGGATACTATCTTTTACAAAGGA
    TTTTCAGAGGAAGAAATTCACCAATTTGAAGGTTTTCAAGAAAGAATTTTGGCGAATCTG
    AAAGAGAAGGGAAATGAGGTTTAG
    60
    120
    180
    240
    300
    360
    420
    444

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN994038_16280 [new locus tag: SPN994038_RS08795 ]
  • symbol: SPN994038_16280
  • description: putative MarR-family transcriptional regulator
  • length: 147
  • theoretical pI: 9.12669
  • theoretical MW: 16621.1
  • GRAVY: -0.410204

⊟Function[edit | edit source]

  • TIGRFAM:
    mobile rSAM pair MarR family regulator (TIGR04472; HMM-score: 101.1)
    and 3 more
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 27.4)
    Signal transduction Regulatory functions DNA interactions CRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 18.2)
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 13.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 31.9)
    MarR_2; MarR family (PF12802; HMM-score: 30.3)
    and 10 more
    HTH_45; Winged helix-turn-helix (PF14947; HMM-score: 22.2)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 22.1)
    Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 17.2)
    HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 16.3)
    Penicillinase_R; Penicillinase repressor (PF03965; HMM-score: 16.1)
    TFIIE_alpha; TFIIE alpha subunit (PF02002; HMM-score: 15.4)
    HTH_IclR; IclR helix-turn-helix domain (PF09339; HMM-score: 14.8)
    HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 14.5)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 13.4)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 12.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9848
    • Cytoplasmic Membrane Score: 0.0089
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0057
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.020456
    • TAT(Tat/SPI): 0.000571
    • LIPO(Sec/SPII): 0.001014
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP31364 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWNSETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQKEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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