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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994038
  • locus tag: SPN994038_RS07000 [old locus tag: SPN994038_13000 ]
  • pan locus tag?: PNEUPAN002782000
  • symbol: SPN994038_RS07000
  • pan gene symbol?: bta
  • synonym:
  • product: thioredoxin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN994038_RS07000 [old locus tag: SPN994038_13000 ]
  • symbol: SPN994038_RS07000
  • product: thioredoxin
  • replicon: chromosome
  • strand: +
  • coordinates: 1322847..1323194
  • length: 348
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021026 (1322847..1323194) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1327 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGGAACAATTTTTAGATAACATCAAAGACCTTGAAGTCACTACAGTTGTGCGTGCGCAA
    GAAGCTCTTGATAAAAAAGAAACTGCAACCTTCTTTATCGGTCGCAAAACTTGCCCTTAC
    TGCCGTAAATTTGCAGGTACATTGTCAGGTGTCGTAGCTGAAACCAAAGCTCACATTTAC
    TTCATCAATAGTGAAGAACCAAGCCAACTCAATGATTTGCAAGCATTCCGCTCACGCTAT
    GGAATCCCAACTGTACCAGGTTTTGTTCATATTACAGATGGACAAATCAACGTCCGTTGC
    GACTCTTCAATGTCAGCACAAGAAATCAAAGATTTCGCAGGATTGTAA
    60
    120
    180
    240
    300
    348

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN994038_RS07000 [old locus tag: SPN994038_13000 ]
  • symbol: SPN994038_RS07000
  • description: thioredoxin
  • length: 115
  • theoretical pI: 5.72652
  • theoretical MW: 12866.5
  • GRAVY: -0.235652

⊟Function[edit | edit source]

  • TIGRFAM:
    putative bacteriocin transport accessory protein (TIGR01295; HMM-score: 157.7)
    and 4 more
    type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (TIGR02738; HMM-score: 22.4)
    glutaredoxin (TIGR02180; HMM-score: 18.5)
    type-F conjugative transfer system pilin assembly protein TrbC (TIGR02742; HMM-score: 12.7)
    TraF-like protein (TIGR02740; HMM-score: 11.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Thioredoxin (CL0172) TraF; F plasmid transfer operon protein (PF13728; HMM-score: 19.9)
    Thioredoxin_2; Thioredoxin-like domain (PF13098; HMM-score: 18.5)
    Thioredoxin; Thioredoxin (PF00085; HMM-score: 17.8)
    Thioredoxin_3; Thioredoxin domain (PF13192; HMM-score: 17.5)
    Glutaredoxin; Glutaredoxin (PF00462; HMM-score: 16.5)
    and 6 more
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 14.7)
    CDA (CL0109) MafB19-deam; MafB19-like deaminase (PF14437; HMM-score: 14.5)
    no clan defined TrbC_Ftype; Type-F conjugative transfer system pilin assembly protein (PF09673; HMM-score: 12.8)
    Thioredoxin (CL0172) Thioredoxin_4; Thioredoxin (PF13462; HMM-score: 12.5)
    DUF6568; Family of unknown function (DUF6568) (PF20207; HMM-score: 12.3)
    no clan defined GxGYxYP_N; GxGYxY sequence motif in domain of unknown function N-terminal (PF16216; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8836
    • Cytoplasmic Membrane Score: 0.0038
    • Cell wall & surface Score: 0.0086
    • Extracellular Score: 0.104
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016197
    • TAT(Tat/SPI): 0.002079
    • LIPO(Sec/SPII): 0.001892
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000434650 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKFAGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDSSMSAQEIKDFAGL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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