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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994038
  • locus tag: SPN994038_RS10255 [old locus tag: SPN994038_18550 ]
  • pan locus tag?: PNEUPAN003713000
  • symbol: SPN994038_RS10255
  • pan gene symbol?: malC
  • synonym:
  • product: ABC transporter permease subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN994038_RS10255 [old locus tag: SPN994038_18550 ]
  • symbol: SPN994038_RS10255
  • product: ABC transporter permease subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 1891532..1892824
  • length: 1293
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021026 (1891532..1892824) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1935 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGAAAAGCAACAACCTAGTAAAGCAGCCCTGCTGTCTATCATTCCTGGGTTAGGACAG
    ATTTACAATAAACAAAAAGCCAAAGGTTTTATCTTCCTTAGTGTAACCATCGTATTTGTC
    CTTTACTTCCTAGCACTTGCAACCCCTGAATTGAGCAACCTCATCACTCTTGGTGACAAA
    CCAGGTCGTGATAATTCCCTCTTTATGCTGATTCGTGGTGCCTTCCATCTAATCTTTGTA
    ATCGTTTATGTACTCTTTTATTTCTCAAATATCAAAGATGCACATACGATTGCAAAACGC
    ATTAACAATGGAATTCCAGTTCCACGCACACTCAAAGACATGATCAAAGGGATTTATGAA
    AATGGCTTCCCTTACCTCTTGATCATTCCATCTTATGTTGCCATGACCTTCGCGATTATC
    TTCCCAGTTATCGTAACCTTGATGATCGCCTTTACCAACTACGACTTCCAACACTTGCCA
    CCAAACAAGTTGTTGGACTGGGTTGGTTTGACCAACTTTACAAACATTTGGAGCTTGAGT
    ACCTTCCGTTCTGCCTTTGGTTCTGTTCTTTCTTGGACTATCATTTGGGCTTTGGCAGCT
    TCTACTTTACAAATCGTAATTGGTATCTTCACAGCTATCATTGCCAACCAACCATTTATC
    AAAGGAAAACGTATCTTTGGTGTTATTTTCCTTCTTCCTTGGGCTGTCCCAGCCTTCATC
    ACTATCTTGACATTCTCAAACATGTTTAACGATAGTGTCGGTGCTATCAACACTCAAGTA
    TTGCCAATCTTGGCTAAATTCCTTCCTTTCCTTGATGGAGCTCTTATTCCTTGGAAAACA
    GACCCAACTTGGACTAAGATTGCCTTGATTATGATGCAAGGTTGGCTCGGATTCCCATAC
    ATCTACGTTTTGACTTTGGGTATCTTGCAATCTATTCCTAACGACCTTTACGAAGCAGCT
    TATATTGACGGTGCCAACGCTTGGCAAAAATTCCGCAACATCACTTTCCCAATGATTTTG
    GCTGTTGCGGCACCTACTTTGATTAGCCAATACACCTTCAACTTTAACAACTTCTCTATC
    ATGTACCTCTTCAATGGTGGAGGACCTGGTAGTGTCGGAGGTGGAGCTGGTTCAACCGAT
    ATCTTGATCTCATGGATCTACCGTTTGACAACAGGTACATCTCCTCAATACTCAATGGCG
    GCAGCTGTTACCTTGATTATCTCTATCATTGTCATCTCAATCTCTATGATCGCATTCAAG
    AAACTACACGCATTTGATATGGAGGACGTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1293

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN994038_RS10255 [old locus tag: SPN994038_18550 ]
  • symbol: SPN994038_RS10255
  • description: ABC transporter permease subunit
  • length: 430
  • theoretical pI: 9.798
  • theoretical MW: 47802.3
  • GRAVY: 0.666047

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 35.1)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 34.2)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 32.8)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 32.1)
    and 3 more
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 27.2)
    2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 19.3)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysW (TIGR02140; HMM-score: 16.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 98.7)
    and 2 more
    no clan defined DUF5683; Family of unknown function (DUF5683) (PF18935; HMM-score: 27.1)
    DUF6677; Family of unknown function (DUF6677) (PF20382; HMM-score: 14.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.037973
    • TAT(Tat/SPI): 0.000797
    • LIPO(Sec/SPII): 0.003714
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000414975 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLSVTIVFVLYFLALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRINNGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLPPNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQPFIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALIPWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNITFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTGTSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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