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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 26-AUG-2017
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPN994039
- locus tag: SPN994039_15190 [new locus tag: SPN994039_RS08220 ]
- pan locus tag?: PNEUPAN003166000
- symbol: SPN994039_15190
- pan gene symbol?: yefM
- synonym:
- product: prevent-host-death family antitoxin
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN994039_15190 [new locus tag: SPN994039_RS08220 ]
- symbol: SPN994039_15190
- product: prevent-host-death family antitoxin
- replicon: chromosome
- strand: -
- coordinates: 1551721..1551990
- length: 270
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: FQ312044 (1551721..1551990) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1551 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241GTGTATAATAGTGGAAAAGAGCTAAAACGAGGTGTGGTTATGGAAGCAGTCCTTTACTCA
ACATTCCGAAATCATTTAAAGGACTACATGAAGAAGGTAAATGATAAATTTGAGCCTTTG
ACGGTGGTCAATAAAAATCCAGATGAGGACATTGTAGTTCTTTCAAAGAGCGAATGGGAC
AGTATTCAGGAAACCCTGAGAATCGCCCAAAATAAGGAGTTATCAGACAAGGTTTTGCGA
GGAATGGATAAAATTCGTGCAGGACACTAG60
120
180
240
270
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN994039_15190 [new locus tag: SPN994039_RS08220 ]
- symbol: SPN994039_15190
- description: prevent-host-death family antitoxin
- length: 89
- theoretical pI: 9.49257
- theoretical MW: 10339.8
- GRAVY: -0.679775
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Toxin production and resistance prevent-host-death family protein (TIGR01552; HMM-score: 62)Mobile and extrachromosomal element functions Other prevent-host-death family protein (TIGR01552; HMM-score: 62)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: Plasmid-antitox (CL0136) PhdYeFM_antitox; Antitoxin Phd_YefM, type II toxin-antitoxin system (PF02604; HMM-score: 52.5)and 3 moreno clan defined YtxH; YtxH-like protein (PF12732; HMM-score: 13.4)CotJB; CotJB protein (PF12652; HMM-score: 12.7)DUF3780; Protein of unknown function (DUF3780) (PF12635; HMM-score: 12.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9624
- Cytoplasmic Membrane Score: 0.006
- Cell wall & surface Score: 0.0007
- Extracellular Score: 0.0308
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002752
- TAT(Tat/SPI): 0.000156
- LIPO(Sec/SPII): 0.00082
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CCP35213 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MYNSGKELKRGVVMEAVLYSTFRNHLKDYMKKVNDKFEPLTVVNKNPDEDIVVLSKSEWDSIQETLRIAQNKELSDKVLRGMDKIRAGH
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1551 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]