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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 05-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPN994039
- locus tag: SPN994039_RS08505 [old locus tag: SPN994039_15740 ]
- pan locus tag?: PNEUPAN003316000
- symbol: SPN994039_RS08505
- pan gene symbol?: pkn1
- synonym:
- product: formylglycine-generating enzyme family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN994039_RS08505 [old locus tag: SPN994039_15740 ]
- symbol: SPN994039_RS08505
- product: formylglycine-generating enzyme family protein
- replicon: chromosome
- strand: -
- coordinates: 1594178..1595026
- length: 849
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_021005 (1594178..1595026) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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841ATGAAAATGAAAAAAATCAAGGGTGGGACATTTATGATGGGAACAAATTCTGAAGAGGGC
TTTTTAGATGATTTTGAAGGTCCTCAAGTCGCTGTTAGTGTAAAGGATTTTTCCATTGCG
GATACTCCAGTTACGAATCAAGAATTTGCTCAATTTGTGAAAGAAACAGGCTATAAAACA
CTAGCTGAGCGACAAGAGTGGTCTTTTGTTTTTATATTGTTCGTTCCGGAGGCAGAAAGG
GAGGGATATCCTCATCCTGCTGGGGCTCCGTGGTGGTTACAAGTTTCGAACGCTTGCTGG
AAACATCCCTACGGTGAGAACAGTAATCTAGTGGGTTTAGAAGACCATCCAGTAGTTCAT
GTTGCTTTAGAAGATGCATTGGCTTTCTGTAATTGGAGCGGAATGTCTTTACCGACTGAA
GCACAGTGGGAATATGCTGCTAGAGGAGGAAGACAATCTGAATATCCTTGGGGAGATACT
CTTTTAGAAGGTGGATATTATCATGCCAATACTTGGCAAGGAAGATTTCCTTATGAAAAT
ACTGCCTTAGATGGATTTATAGGAACGGCTCCTGTCTATGAATTTTTACCTAATGATTTT
GGTCTATATCAAATGATTGGGAATGTTTGGGAATGGTGTCGCAATCCGAGATATACCTTA
TTAGCTAGTTTTAATGAAGATGACTATGAGTTACCAAAATATGGGATACAAGATGAGGAG
TATGCTATCAGAGGAGGTTCCTTTTTATGTCATTGTTCTTATTGTAATCGATACCGAGTA
GCTGCTAGAAATGGATGTATTTCTACTTCCACTAGTAGCCATCTAGGTTTTAGATGTTTG
AAAGAATAG60
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849
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN994039_RS08505 [old locus tag: SPN994039_15740 ]
- symbol: SPN994039_RS08505
- description: formylglycine-generating enzyme family protein
- length: 282
- theoretical pI: 4.60031
- theoretical MW: 32105.6
- GRAVY: -0.439362
⊟Function[edit | edit source]
- reaction: EC 1.8.3.-? ExPASy
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs ergothioneine biosynthesis protein EgtB (TIGR03440; HMM-score: 106.9)gliding motility-associated lipoprotein GldK (TIGR03529; HMM-score: 96.3)and 5 moregliding motility-associated lipoprotein GldK (TIGR03525; HMM-score: 81.4)Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs 5-histidylcysteine sulfoxide synthase (TIGR04344; HMM-score: 61.9)gliding motility-associated lipoprotein GldJ (TIGR03530; HMM-score: 42.5)gliding motility-associated lipoprotein GldJ (TIGR03524; HMM-score: 33.8)fibrobacter succinogenes paralogous family TIGR02171 (TIGR02171; HMM-score: 23.2)
- TheSEED: data available for Hungary19A-6
- PFAM: C_Lectin (CL0056) FGE-sulfatase; Sulfatase-modifying factor enzyme 1 (PF03781; HMM-score: 235.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.7444
- Cytoplasmic Membrane Score: 0.0703
- Cell wall & surface Score: 0.0011
- Extracellular Score: 0.1842
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.013863
- TAT(Tat/SPI): 0.00037
- LIPO(Sec/SPII): 0.001446
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000782429 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPVTNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKHPYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDTLLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRYTLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLGFRCLKE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]